Process for preparing a deuterated or tritiated compound

Klei, Steven R.; Bergman, Robert C.

Title: Process for preparing a deuterated or tritiated compound

Patent · Tue Jun 06 00:00:00 EDT 2006

OSTI ID:1175779

Klei, Steven R.; Bergman, Robert C.

A process for labeling organic compounds with deuterium and tritium is described using specific catalysts.

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Research Organization:: Univ. of California, Oakland, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 7,057,055

Application Number:: 11/243,852

OSTI ID:: 1175779

Country of Publication:: United States

Language:: English

References (26)

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Iridium(III) and Rhodium(III) Complexes Bearing Chelating Cyclopentadienyl−Phosphine Ligands as C−H Activation Catalysts for the Deuteration of Hydrocarbons in D ₂ O Klei, Steven R.; Tilley, T. Don; Bergman, Robert G. Organometallics, Vol. 21, Issue 23 https://doi.org/10.1021/om020375o	journal	November 2002
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Activation of water molecule. 2. Generation of strong hydroxo bases by the reaction of water with platinum(0) phosphine complexes and the applications as catalysts for hydrogen-deuterium exchange and hydration reactions Yoshida, Toshikatsu; Matsuda, Tadao; Okano, Tamon Journal of the American Chemical Society, Vol. 101, Issue 8 https://doi.org/10.1021/ja00502a017	journal	April 1979
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Synthesis, characterization, and reaction chemistry of new trifluoromethanesulfonato complexes of rhodium and iridium: formation of cationic rhodium-platinum and iridium-platinum heterobinuclear complexes with bridging chloride ligands Stang, Peter J.; Huang, Yo Hsin; Arif, Atta M. Organometallics, Vol. 11, Issue 1 https://doi.org/10.1021/om00037a043	journal	January 1992
Iridium-Catalyzed H/D Exchange into Organic Compounds in Water Klei, Steven R.; Golden, Jeffrey T.; Tilley, T. Don Journal of the American Chemical Society, Vol. 124, Issue 10 https://doi.org/10.1021/ja017219d	journal	March 2002
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Hydrogen/Deuterium Exchange Reactions and Transfer Hydrogenations Catalyzed by [C ₅ Me ₅ Rh(olefin) ₂ ] Complexes: Conversion of Alkoxysilanes to Silyl Enolates ^† Lenges, Christian P.; White, Peter S.; Brookhart, Maurice Journal of the American Chemical Society, Vol. 121, Issue 18 https://doi.org/10.1021/ja984409o	journal	May 1999
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Cationic Ir(III) alkyl and hydride complexes: stoichiometric and catalytic CH activation by Cp∗(PMe3)Ir(R)(X) in homogeneous solution Klei, Steven R.; Golden, Jeffrey T.; Burger, Peter Journal of Molecular Catalysis A: Chemical, Vol. 189, Issue 1 https://doi.org/10.1016/S1381-1169(02)00192-9	journal	October 2002

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