skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth

Patent ·
OSTI ID:1175602

The invention provides method for assessing tumorigenicity of mammalian cells by assaying the proteolytic fragments of 120-130 kD alpha-dystroglycan in medium surrounding mammalian cells.

Research Organization:
Univ. of California, Oakland, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC03-76SF0098
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
6,982,151
Application Number:
09/652,493
OSTI ID:
1175602
Country of Publication:
United States
Language:
English

References (8)

A Role for Dystroglycan in Basement Membrane Assembly journal December 1998
Functional Rescue of the Sarcoglycan Complex in the BIO 14.6 Hamster Using δ-Sarcoglycan Gene Transfer journal May 1998
Value of Prostate-Specific Antigen as a Tumor Marker journal January 1993
Non-muscle alpha-dystroglycan is involved in epithelial development. journal July 1995
Another Anniversary for the War on Cancer journal March 1994
A Role of Dystroglycan in Schwannoma Cell Adhesion to Laminin journal May 1997
Differential expression of dystrophin, utrophin and dystrophin-associated proteins in peripheral nerve journal November 1993
Reduced expression of dystroglycan in breast and prostate cancer journal August 2001

Similar Records

Related Subjects