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Title: High performance hybrid magnetic structure for biotechnology applications

Patent ·
OSTI ID:1175524

The present disclosure provides a high performance hybrid magnetic structure made from a combination of permanent magnets and ferromagnetic pole materials which are assembled in a predetermined array. The hybrid magnetic structure provides means for separation and other biotechnology applications involving holding, manipulation, or separation of magnetizable molecular structures and targets. Also disclosed are: a method of assembling the hybrid magnetic plates, a high throughput protocol featuring the hybrid magnetic structure, and other embodiments of the ferromagnetic pole shape, attachment and adapter interfaces for adapting the use of the hybrid magnetic structure for use with liquid handling and other robots for use in high throughput processes.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC03-76SF00098
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
6,954,128
Application Number:
10/305,658
OSTI ID:
1175524
Country of Publication:
United States
Language:
English

References (3)

High-Throughput Plasmid Purification for Capillary Sequencing journal July 2001
Magnetic Bead Purification of Labeled DNA Fragments for High-Throughput Capillary Electrophoresis Sequencing journal June 2002
The U5.0 undulator design for the advanced light source at LBL
  • Hoyer, E.; Chin, J.; Halbach, K.
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 291, Issue 1-2 https://doi.org/10.1016/0168-9002(90)90091-J
journal May 1990