Method for detecting pathogens attached to specific antibodies
Patent
·
OSTI ID:1175213
The use of impedance measurements to detect the presence of pathogens attached to antibody-coated beads. In a fluidic device antibodies are immobilized on a surface of a patterned interdigitated electrode. Pathogens in a sample fluid streaming past the electrode attach to the immobilized antibodies, which produces a change in impedance between two adjacent electrodes, which impedance change is measured and used to detect the presence of a pathogen. To amplify the signal, beads coated with antibodies are introduced and the beads would stick to the pathogen causing a greater change in impedance between the two adjacent electrodes.
- Research Organization:
- The Regents of the Univ. of California, Oakland, CA (United States); Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-7405-ENG-48
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Number(s):
- 6,846,639
- Application Number:
- 09/993,870
- OSTI ID:
- 1175213
- Country of Publication:
- United States
- Language:
- English
Similar Records
Impedance measurements for detecting pathogens attached to antibodies
Automated RNA Extraction and Purification for Multiplexed Pathogen Detection
Using impedance measurements for detecting pathogens trapped in an electric field
Patent
·
Tue Dec 28 00:00:00 EST 2004
·
OSTI ID:1175213
Automated RNA Extraction and Purification for Multiplexed Pathogen Detection
Journal Article
·
Sat Jan 01 00:00:00 EST 2005
· Journal of Undergraduate Research
·
OSTI ID:1175213
Using impedance measurements for detecting pathogens trapped in an electric field
Patent
·
Tue Jul 20 00:00:00 EDT 2004
·
OSTI ID:1175213