High throughput microcantilever detector

Patent · Tue Jul 20 00:00:00 EDT 2004

OSTI ID:1174950

Thundat, Thomas G.; Ferrell, Thomas L.; Hansen, Karolyn M.; Tian, Fang

In an improved uncoated microcantilever detector, the sample sites are placed on a separate semi-conducting substrate and the microcantilever element detects and measures the changes before and after a chemical interaction or hybridization of the sites by sensing differences of phase angle between an alternating voltage applied to the microcantilever element and vibration of the microcantilever element. In another embodiment of the invention, multiple sample sites are on a sample array wherein an array of microcantilever elements detect and measure the change before and after chemical interactions or hybridizations of the sample sites.

• Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-00OR22725
• Assignee: UT-Battelle, LLC (Oak Ridge, TN)
• Patent Number(s): 6,763,705
• Application Number: 10/462,249
• OSTI ID: 1174950
• Country of Publication: United States
• Language: English

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