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Title: Methods for the survey and genetic analysis of populations

Patent ·
OSTI ID:1174472

The present invention relates to methods for performing surveys of the genetic diversity of a population. The invention also relates to methods for performing genetic analyses of a population. The invention further relates to methods for the creation of databases comprising the survey information and the databases created by these methods. The invention also relates to methods for analyzing the information to correlate the presence of nucleic acid markers with desired parameters in a sample. These methods have application in the fields of geochemical exploration, agriculture, bioremediation, environmental analysis, clinical microbiology, forensic science and medicine.

Research Organization:
~Individually Owned Patent
Sponsoring Organization:
USDOE
DOE Contract Number:
FC36-01GO11016
Assignee:
Ashby, Matthew
Patent Number(s):
6,613,520
Application Number:
09/829,855
OSTI ID:
1174472
Country of Publication:
United States
Language:
English

References (7)

Serial Analysis of Gene Expression journal October 1995
Detection and Identification of Previously Unrecognized Microbial Pathogens journal September 1998
Impact of Culture-Independent Studies on the Emerging Phylogenetic View of Bacterial Diversity journal September 1998
Characterization of microbial diversity by determining terminal restriction fragment length polymorphisms of genes encoding 16S rRNA. journal January 1997
Gene Expression Profiles in Normal and Cancer Cells journal May 1997
Effect of genome size and rrn gene copy number on PCR amplification of 16S rRNA genes from a mixture of bacterial species. journal January 1995
A Molecular View of Microbial Diversity and the Biosphere journal May 1997

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59 BASIC BIOLOGICAL SCIENCES