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Title: Microwave heating of aqueous samples on a micro-optical-electro-mechanical system

Patent ·
OSTI ID:1171653

Apparatus for heating a sample includes a microchip; a microchannel flow channel in the microchip, the microchannel flow channel containing the sample; a microwave source that directs microwaves onto the sample for heating the sample; a wall section of the microchannel flow channel that receives the microwaves and enables the microwaves to pass through wall section of the microchannel flow channel, the wall section the microchannel flow channel being made of a material that is not appreciably heated by the microwaves; a carrier fluid within the microchannel flow channel for moving the sample in the microchannel flow channel, the carrier fluid being made of a material that is not appreciably heated by the microwaves; wherein the microwaves pass through wall section of the microchannel flow channel and heat the sample.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
8,969,767
Application Number:
12/326,594
OSTI ID:
1171653
Resource Relation:
Patent File Date: 2008 Dec 02
Country of Publication:
United States
Language:
English

References (8)

Microwave dielectric heating of fluids in an integrated microfluidic device journal October 2007
Microwave-assisted high-speed PCR journal February 2003
Bounds for local and average microwave absorption in heterogeneous systems journal February 2008
The microwave absorption of emulsions containing aqueous micro- and nanodroplets: A means to optimize microwave heating journal October 2006
Microfluidic devices with monolithic microwave integrated circuits patent August 2003
System and method for confining an object to a region of fluid flow having a stagnation point patent March 2006
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture patent-application July 2008
System and Method for Rapid Thermal Cycling patent-application July 2008