Oxidative stress, inflammation, and cancer: How are they linked?
|
journal
|
December 2010 |
Endogenous DNA damage in humans: a review of quantitative data
|
journal
|
May 2004 |
Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.
|
journal
|
June 1990 |
DNA precursor pool: a significant target for N-methyl-N-nitrosourea in C3H/10T1/2 clone 8 cells.
|
journal
|
April 1982 |
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
|
journal
|
April 2014 |
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
|
journal
|
April 2014 |
Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics
|
journal
|
April 2012 |
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
|
journal
|
January 1991 |
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase replication fidelity
|
journal
|
February 2008 |
NMR studies of a DNA containing 8-hydroxydeoxyguanosine
|
journal
|
January 1991 |
Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions
|
journal
|
January 2010 |
Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo
|
journal
|
September 2002 |
Structure and Mechanism of DNA Polymerase β
|
journal
|
April 2014 |
Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.
|
journal
|
January 1991 |
Crystal Structures of Human DNA Polymerase β Complexed with Gapped and Nicked DNA: Evidence for an Induced Fit Mechanism † , ‡
|
journal
|
September 1997 |
Magnesium-Induced Assembly of a Complete DNA Polymerase Catalytic Complex
|
journal
|
April 2006 |
Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site
|
journal
|
June 2010 |
8-OxodGTP Incorporation by DNA Polymerase β Is Modified by Active-Site Residue Asn279 †
|
journal
|
February 2000 |
Distinct energetics and closing pathways for DNA polymerase β with 8-oxoG template and different incoming nucleotides
|
journal
|
January 2007 |
DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion
|
journal
|
December 2012 |
Single-turnover Kinetic Analysis of the Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine during Gap-filling Synthesis Catalyzed by Human DNA Polymerases λ and β
|
journal
|
April 2007 |
Crystal Structure of DNA Polymerase β with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position
|
journal
|
March 2014 |
Observing a DNA Polymerase Choose Right from Wrong
|
journal
|
July 2013 |
Watching DNA polymerase η make a phosphodiester bond
|
journal
|
July 2012 |
DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State †
|
journal
|
January 2008 |
Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage
|
journal
|
July 2009 |
[20] Processing of X-ray diffraction data collected in oscillation mode
|
book
|
January 1997 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
|
journal
|
January 2010 |
Coot model-building tools for molecular graphics
|
journal
|
November 2004 |
Influence of DNA Structure on DNA Polymerase β Active Site Function: EXTENSION OF MUTAGENIC DNA INTERMEDIATES
|
journal
|
May 2004 |
Atomic charges derived from electrostatic potentials: A detailed study
|
journal
|
September 1987 |
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
|
journal
|
July 1983 |
Constant pressure molecular dynamics simulation: The Langevin piston method
|
journal
|
September 1995 |
Particle mesh Ewald: An N ⋅log( N ) method for Ewald sums in large systems
|
journal
|
June 1993 |
Scalable molecular dynamics with NAMD
|
journal
|
January 2005 |
All-atom empirical force field for nucleic acids: I. Parameter optimization based on small molecule and condensed phase macromolecular target data
|
journal
|
January 2000 |
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins †
|
journal
|
April 1998 |
All-atom empirical force field for nucleic acids: II. Application to molecular dynamics simulations of DNA and RNA in solution
|
journal
|
January 2000 |
Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass
|
journal
|
January 2006 |
Improving the specificity of organophosphorus hydrolase to acephate by mutagenesis at its binding site: a computational study
|
journal
|
May 2021 |
Structure and Mechanism of DNA Polymerase β
|
journal
|
February 2006 |
The preliminary investigation of potential response biomarkers to PAHs exposure on childhood asthma
|
journal
|
May 2021 |
Mechanism of pore opening in the calcium-activated chloride channel TMEM16A
|
journal
|
February 2021 |
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
|
journal
|
February 2021 |
DNA precursor pool: a significant target for N-methyl-N-nitrosourea in C3H/10T1/2 clone 8 cells.
|
text
|
January 1982 |
Structural basis for the 3′ – 5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism
|
book
|
August 2020 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
|
text
|
January 2010 |
A molecular mechanics force field for NAD+ NADH, and the pyrophosphate groups of nucleotides
|
journal
|
January 1997 |
Structure and Mechanism of DNA Polymerase β
|
journal
|
May 2006 |
The Mammalian Mismatch Repair Pathway Removes DNA 8-oxodGMP Incorporated from the Oxidized dNTP Pool
|
journal
|
June 2002 |
Structural Insights into the Origins of DNA Polymerase Fidelity
|
journal
|
May 2003 |
Loss of DNA Polymerase β Stacking Interactions with Templating Purines, but Not Pyrimidines, Alters Catalytic Efficiency and Fidelity
|
journal
|
December 2001 |
Human POLB Gene Is Mutated in High Percentage of Colorectal Tumors
|
journal
|
May 2012 |
Structural Basis for Promutagenicity of 8-Halogenated Guanine
|
journal
|
January 2014 |
Watching a DNA polymerase in action
|
journal
|
January 2014 |