Microorganisms having enhanced resistance to acetate and methods of use

Brown, Steven D; Yang, Shihui

Title: Microorganisms having enhanced resistance to acetate and methods of use

Patent · Tue Oct 21 00:00:00 EDT 2014

OSTI ID:1160260

Brown, Steven D; Yang, Shihui

The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: ACO5-000R22725

Assignee:: UT-Batelle, LLC (Oakridge, TN)

Patent Number(s):: 8,865,440

Application Number:: 13/688,636

OSTI ID:: 1160260

Resource Relation:: Patent File Date: 2012 Nov 29

Country of Publication:: United States

Language:: English

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