Microbes encapsulated within crosslinkable polymers

Chidambaram, Devicharan; Liu, Ying; Rafailovich, Miriam H

Title: Microbes encapsulated within crosslinkable polymers

Patent · Tue Feb 05 00:00:00 EST 2013

OSTI ID:1083227

Chidambaram, Devicharan; Liu, Ying; Rafailovich, Miriam H

The invention relates to porous films comprising crosslinked electrospun hydrogel fibers. Viable microbes are encapsulated within the crosslinked electrospun hydrogel fibers. The crosslinked electrospun hydrogel fibers are water insoluble and permeable. The invention also relates to methods of making and using such porous films.

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Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-98CH10886

Assignee:: Brookhaven Science Associates, LLC (Upton, NY); The Research Foundation of State University of New York (Stony Brook, NY)

Patent Number(s):: 8,367,109

Application Number:: 12/420,088

OSTI ID:: 1083227

Country of Publication:: United States

Language:: English

References (9)

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Methods and compositions for assaying analytes Yuan, Chong-Sheng https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6376210 US Patent Document 6,376,210	patent	April 2002
Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications Chu, Benjamin; Hsiao, Benjamin S.; Fang, Dufei https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7172765 US Patent Document 7,172,765	patent	February 2007
Microbial sensor for aspartame Renneberg, R.; Riedel, K.; Scheller, F. Applied Microbiology and Biotechnology, Vol. 21, Issue 3-4 https://doi.org/10.1007/BF00295116	journal	February 1985
Smart Hydrogels for in Situ Generated Implants ^† Cohn, Daniel; Sosnik, Alejandro; Garty, Shai Biomacromolecules, Vol. 6, Issue 3 https://doi.org/10.1021/bm0495250	journal	May 2005
Novel Biohybrid Materials by Electrospinning: Nanofibers of Poly(ethylene oxide) and Living Bacteria Gensheimer, M.; Becker, M.; Brandis-Heep, A. Advanced Materials, Vol. 19, Issue 18 https://doi.org/10.1002/adma.200602936	journal	September 2007
Structure and Nanomechanical Characterization of Electrospun PS/Clay Nanocomposite Fibers Ji, Yuan; Li, Bingquan; Ge, Shouren Langmuir, Vol. 22, Issue 3 https://doi.org/10.1021/la0525022	journal	January 2006
Encapsulation of bacteria and viruses in electrospun nanofibres Salalha, W.; Kuhn, J.; Dror, Y. Nanotechnology, Vol. 17, Issue 18 https://doi.org/10.1088/0957-4484/17/18/025	journal	August 2006

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