APPLICATION OF THE THEORY OF INTERACTING CONTINUA TO BLOOD FLOW
Micro-scale investigations of the flow and deformation of blood and its formed elements have been studied for many years. Early in vitro investigations in the rotational viscometers or small glass tubes revealed important rheological properties such as the reduced blood apparent viscosity, Fahraeus effect and Fahraeus-Lindqvist effect [1], exhibiting the nonhomogeneous property of blood in microcirculation. We have applied Mixture Theory, also known as Theory of Interacting Continua, to study and model this property of blood [2, 3]. This approach holds great promise for predicting the trafficking of RBCs in micro-scale flows (such as the depletion layer near the wall), and other unique hemorheological phenomena relevant to blood trauma. The blood is assumed to be composed of an RBC component modeled as a nonlinear fluid, suspended in plasma, modeled as a linearly viscous fluid.
- Research Organization:
- National Energy Technology Lab. (NETL), Pittsburgh, PA, and Morgantown, WV (United States). In-house Research
- Sponsoring Organization:
- USDOE FE Office of Clean Coal (FE-20)
- OSTI ID:
- 1036464
- Report Number(s):
- NETL-PUB-236; TRN: US201206%%328
- Resource Relation:
- Conference: Proceedings of the ASME 2011 Summer Bioengineering Conference SBC2011, June 22-25, Nemacolin Woodlands Resort, Farmington, Pennsylvania, USA
- Country of Publication:
- United States
- Language:
- English
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