skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Methods for the synthesis of olefins and derivatives

Patent ·
OSTI ID:1027114
 [1];  [1];  [2];  [3];  [1]
  1. San Diego, CA
  2. Encinitas, CA
  3. Bellefonte, PA
+ Show Author Affiliations

The invention provides a method of producing acrylic acid. The method includes contacting fumaric acid with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylic acid per mole of fumaric acid. Also provided is an acrylate ester. The method includes contacting fumarate diester with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylate ester per mole of fumarate diester. An integrated process for process for producing acrylic acid or acrylate ester is provided which couples bioproduction of fumaric acid with metathesis transformation. An acrylic acid and an acrylate ester production also is provided.

Research Organization:
Genomatica, Inc. (San Diego, CA)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-07ER84865; FG02-06ER84536
Assignee:
Genomatica, Inc. (San Diego, CA)
Patent Number(s):
8,026,386
Application Number:
12/188,582
OSTI ID:
1027114
Country of Publication:
United States
Language:
English

References (1189)

Methanol: Coenzyme M Methyltransferase from Methanosarcina Barkeri. Purification, Properties and Encoding Genes of the Corrinoid Protein MT1 journal February 1997
Effect of Sorghum vulgare phosphoenolpyruvate carboxylase and Lactococcus lactis pyruvate carboxylase coexpression on succinate production in mutant strains of Escherichia coli journal November 2004
Acetate and ethanol production from H2 and CO2by Moorella sp. using a repeated batch culture journal March 2005
An efficient succinic acid production process in a metabolically engineered Corynebacterium glutamicum strain journal September 2008
Biochemical and functional properties of a pyruvate formate-lyase (PFL)-activating system in Streptococcus mutans journal October 2003
Utilization of Electrically Reduced Neutral Red byActinobacillus succinogenes: Physiological Function of Neutral Red in Membrane-Driven Fumarate Reduction and Energy Conservation journal January 1999
Directed evolution of biocatalytic processes journal June 2005
Localization of NAD-Isocitrate Dehydrogenase and Glutamate Dehydrogenase in Rice Roots: Candidates for Providing Carbon Skeletons to NADH-Glutamate Synthase journal October 2005
Sequence saturation mutagenesis with tunable mutation frequencies journal June 2005
Phosphotransbutyrylase Expression in Bacillus megaterium journal May 2001
The cloning and characterization of the arom gene of Pneumocystis carinii journal December 1993
Metabolic flux profiling of Escherichia coli mutants in central carbon metabolism using GC-MS: Metabolic flux profiling in E.���coli journal March 2003
A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae journal January 1993
Cloning, sequencing, and overexpression of the genes encoding coenzyme B12-dependent glycerol dehydratase of Citrobacter freundii. journal January 1996
Purification and Characterization of Fumarase from Corynebacterium glutamicum journal May 2006
Functional Characterization and Localization of Acetyl-CoA Hydrolase, Ach1p, in Saccharomyces cerevisiae journal February 2003
Effects of dissolved CO2 levels on the growth of Mannheimia succiniciproducens and succinic acid production journal December 2007
4- O -Phosphoryl- l -threonine, a substrate of the pdx C( ser C) gene product involved in vitamin B 6 biosynthesis journal July 1996
Enhanced Isoamyl Acetate Production upon Manipulation of the Acetyl-CoA Node in Escherichia coli journal June 2004
The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale journal September 2005
Olefin metathesis journal August 2004
Cloning of Baeyer-Villiger monooxygenases from Comamonas, Xanthobacter and Rhodococcus using polymerase chain reaction with highly degenerate primers journal March 2003
Pyruvate:NADP+ oxidoreductase from Euglena gracilis: The kinetic properties of the enzyme journal November 1989
Codon choice in genes depends on flanking sequence information—implications for theoretical reverse translation journal January 2008
Dehydration of ( R )-2-hydroxyacyl-CoA to enoyl-CoA in the fermentation of α-amino acids by anaerobic bacteria journal October 2004
Regulation of alcohol fermentation in Escherichia coli. Progress report, July 1991--June 1994 report August 1994
Purification and characterization of the 4-aminobutyrate-2-ketoglutarate transaminase from mouse brain journal July 1973
An apparent Bacillus subtilis folic acid biosynthetic operon containing pab, an amphibolic trpG gene, a third gene required for synthesis of para-aminobenzoic acid, and the dihydropteroate synthase gene. journal January 1990
2-Amino-2-deoxyisochorismate Is a Key Intermediate in Bacillus subtilis p- Aminobenzoic Acid Biosynthesis journal March 2009
Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network journal February 2003
Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16 journal September 2006
The Structure and Mechanism of the Type II Dehydroquinase from Streptomyces coelicolor journal April 2002
A new process for the continuous production of succinic acid from glucose at high yield, titer, and productivity journal January 2007
4-Hydroxybutyryl-CoA Dehydratase from Clostridium aminobutyricum: Characterization of FAD and Iron−Sulfur Clusters Involved in an Overall Non-Redox Reaction journal September 1996
Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae journal January 2001
Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex journal March 1992
Effects of biomass-generated producer gas constituents on cell growth, product distribution and hydrogenase activity of Clostridium carboxidivorans P7T journal July 2006
Production of fumaric acid by fermentation of enzymatic hydrolysates derived from cassava bagasse journal April 1999
Metabolic engineering of Escherichia coli to enhance recombinant protein production through acetate reduction journal July 1995
Amino acid sequence of alcohol dehydrogenase from the thermophilic bacterium Thermoanaerobium brockii journal August 1989
Identification and analysis of a glutaryl-CoA dehydrogenase-encoding gene and its cognate transcriptional regulator from Azoarcus sp. CIB journal February 2008
Enhanced production of cis,cis-muconate in a cell-recycle bioreactor journal January 1997
Expression of Two Escherichia coli Acetyl-CoA Carboxylase Subunits Is Autoregulated journal October 2003
Fed-batch culture of a metabolically engineeredEscherichia coli strain designed for high-level succinate production and yield under aerobic conditions journal January 2005
Fermentation of biomass-generated synthesis gas: Effects of nitric oxide journal January 2007
Yeast pyruvate carboxylase: Identification of two genes encoding isoenzymes journal May 1991
Structures of Isobutyryl-CoA Dehydrogenase and Enzyme-Product Complex: COMPARISON WITH ISOVALERYL- AND SHORT-CHAIN ACYL-COA DEHYDROGENASES journal January 2004
Critical catalytic functional groups in the mechanism of aspartate-β-semialdehyde dehydrogenase journal September 2004
Acetylpolyamine amidohydrolase from Mycoplana ramosa: gene cloning and characterization of the metal-substituted enzyme. journal January 1996
Mutations affecting the enzymes involved in the utilization of 4-aminobutyric acid as nitrogen source by the yeast Saccharomyces cerevisiae journal June 1985
The role of substrate-binding groups in the mechanism of aspartate-β-semialdehyde dehydrogenase journal July 2004
Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: isolation and characterization of a phosphinothricin-specific transaminase from Escherichia coli. journal January 1990
Evaluation of succinic acid continuous and repeat-batch biofilm fermentation by Actinobacillus succinogenes using plastic composite support bioreactors journal June 2004
The Effects of Feed and Intracellular Pyruvate Levels on the Redistribution of Metabolic Fluxes in Escherichia coli journal April 2001
Substrate Specificity and Identification of Functional Groups of Homoserine Kinase from Escherichia coli † journal January 1996
Study of an alternate glyoxylate cycle for acetate assimilation by Rhodobacter sphaeroides journal July 2006
X-ray crystallographic and kinetic correlation of a clinically observed human fumarase mutation journal June 2002
Characterization of the genes encoding beta-ketoadipate: succinyl-coenzyme A transferase in Pseudomonas putida. journal January 1992
Metabolic Engineering of Ammonium Assimilation in Xylose-Fermenting Saccharomyces cerevisiae Improves Ethanol Production journal August 2003
Characterization of the 6-aminohexanoate-dimer hydrolase from Pseudomonas sp. NK87 journal April 1993
Expression and Molecular Analysis of the Arabidopsis DXR Gene Encoding 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase, the First Committed Enzyme of the 2- C -Methyl-d-Erythritol 4-Phosphate Pathway journal July 2002
Characterization of isocitrate dehydrogenase from the green sulfur bacterium Chlorobium limicola: A carbon dioxide-fixing enzyme in the reductive tricarboxylic acid cycle journal April 2002
Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding .beta.-methylaspartase and characterization of the recombinant protein journal November 1992
Functional analysis of structural genes for NAD + -dependent formate dehydrogenase in Saccharomyces cerevisiae: Formate dehydrogenase genes in S. cerevisiae journal February 2002
Nonribosomal peptides: from genes to products journal January 2003
Recombinant Expression, Purification, and Characterization of Three Isoenzymes of Aspartate Aminotransferase fromArabidopsis thaliana journal April 1998
Purification of two alcohol dehydrogenases from Zymomonas mobilis and their properties journal August 1985
Probing the Roles of Key Residues in the Unique Regulatory NADH Binding Site of Type II Citrate Synthase of Escherichia coli journal June 2003
Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene. journal March 1992
Mammalian 3-Hydroxyisobutyrate Dehydrogenase book January 2000
Effects of cultivation gas phase on hydrogenase of the acetogen Clostridium thermoaceticum. journal January 1984
Production of the Long-Chain Alcohols Octanol, Decanol, and Dodecanol by Escherichia coli journal June 2005
Directed Molecular Evolution of Cytochrome c Peroxidase † journal September 2000
[13C]propionate oxidation in wild-type and citrate synthase mutant Escherichia coli: evidence for multiple pathways of propionate utilization journal May 1993
Crystalline 3-methylaspartase from a facultative anaerobe, Escherichia coli strain YG1002 journal May 1994
Molecular organization of the Escherichia coli gab cluster: nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene journal December 1993
Stereochemical imperative in enzymic decarboxylations. Stereochemical course of the decarboxylation catalyzed by acetoacetate decarboxylase journal August 1984
Butanol tolerance and autobacteriocin production byClostridium acetobutylicum journal September 1987
The alcohol dehydrogenases of Saccharomyces cerevisiae: a comprehensive review journal November 2008
5487987 Synthesis of adipic acid from biomass-derived carbon sources journal January 1997
Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: A study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile journal September 2005
Genetic Control by a Metabolite Binding mRNA journal September 2002
Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol journal September 2005
Probabilistic path ranking based on adjacent pairwise coexpression for metabolic transcripts analysis journal November 2007
Rapid Evolution of Novel Traits in Microorganisms journal August 2001
Gene cloning, heterologous overexpression and optimized refolding of the NAD-glutamate dehydrogenase from Haloferax mediterranei journal October 2005
Cloning and Expression of pca Genes from Pseudomonas putida in Escherichia coli journal November 1988
Properties of L-Lysine ε-Dehydrogenase from Agrobacterium tumefaciens1 journal June 1989
A New Type of a Multifunctional β-Oxidation Enzyme in Euglena journal January 2003
Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Cloning, Characterization, and Analysis of Sequences Encoding 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase journal January 2002
Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. journal July 1990
Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry to the Detection of γ-Hydroxybutyric Acid and Its Precursors in Various Materials journal October 2004
Fermentative Production of Chemicals That Can Be Used for Polymer Synthesis journal March 2004
Complete nucleotide sequence of the Escherichia coli gdhA gene journal January 1983
Recombinant tyrosine aminotransferase from Trypanosoma cruzi: structural characterization and site directed mutagenesis of a broad substrate specificity enzyme journal April 2001
The Flp Recombinase of th 2-μm Plasmid of Saccharomyces cerevisiae book January 1995
Purification and Characterization of Two Extremely Thermostable Enzymes, Phosphate Acetyltransferase and Acetate Kinase, from the Hyperthermophilic Eubacterium Thermotoga maritima journal March 1999
Multiple β-Ketothiolases Mediate Poly(β-Hydroxyalkanoate) Copolymer Synthesis in Ralstonia eutropha journal April 1998
Propionyl-CoA condensing enzyme from Ascaris muscle mitochondria journal February 1991
Characterization of L-Lysine 6-Aminotransferase and Its Structural Gene from Flavobacterium lutescens IFO3084 journal September 2000
Purification and characterization of a primary-secondary alcohol dehydrogenase from two strains of Clostridium beijerinckii. journal January 1993
Libraries of hybrid proteins from distantly related sequences journal May 2001
Properties and sequence of the coenzyme B 12 -dependent glycerol dehydratase of Clostridium pasteurianum journal July 1998
Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms journal June 2003
Purification, Properties, and Sequencing of Aminoisobutyrate Aminotransferases from Rat Liver book January 2000
Mechanism of the Clostridium thermoaceticum Pyruvate:Ferredoxin Oxidoreductase:  Evidence for the Common Catalytic Intermediacy of the Hydroxyethylthiamine Pyropyrosphate Radical † journal July 1997
Structural constraints on protein self-processing in L-aspartate- -decarboxylase journal December 2003
Biochemical and molecular characterization of a succinate semialdehyde dehydrogenase involved in the catabolism of 4-hydroxybutyric acid in Ralstonia eutropha journal December 1999
Ultrasound-mediated DNA transfer for bacteria journal October 2007
Melamine Deaminase and Atrazine Chlorohydrolase: 98 Percent Identical but Functionally Different journal April 2001
Purification and Properties of Acetyl-CoA Synthetase (ADP-forming), an Archaeal Enzyme of Acetate Formation and ATP Synthesis, from the Hyperthermophile Pyrococcus furiosus journal March 1997
Site-directed Mutagenesis of Escherichia coli Acetylglutamate Kinase and Aspartokinase III Probes the Catalytic and Substrate-binding Mechanisms of these Amino Acid Kinase Family Enzymes and Allows Three-dimensional Modelling of Aspartokinase journal November 2003
Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids journal November 1998
Molecular Cloning, Nucleotide Sequencing, and Expression of Genes Encoding Alcohol Dehydrogenases From the ThermophileThermoanaerobacter brockiiand the MesophileClostridium beijerinckii journal August 1997
Alteration of the Substrate Specificity of Benzoylformate Decarboxylase from Pseudomonas putida by Directed Evolution journal August 2003
Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-?-xylulose 5-phosphate reductoisomerase journal October 2000
Quantitative analysis of ribosome binding sites in E.coli journal January 1994
Lactate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: the crystal structure at 2.1 å resolution reveals strategies for intrinsic protein stabilization journal June 1998
Multiple interactions of lysine-128 of Escherichia coli glutamate dehydrogenase revealed by site-directed mutagenesis studies journal January 1988
The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens journal September 2004
Differential expression of hydrogenase isoenzymes in Escherichia coli K-12: evidence for a third isoenzyme. journal January 1985
Structure of Staphylococcus aureus 1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA
  • Ulaganathan, Venkatasubramanian; Agacan, Mark F.; Buetow, Lori
  • Acta Crystallographica Section F Structural Biology and Crystallization Communications, Vol. 63, Issue 11 https://doi.org/10.1107/S1744309107047720
journal October 2007
Two beta-alanyl-CoA:ammonia lyases in Clostridium propionicum: Beta-alanyl-CoA:ammonia lyases journal January 2005
Spermidine/spermine N 1 ‐acetyltransferase — the turning point in polyamine metabolism journal May 1993
Degenerate Oligonucleotide Gene Shuffling book January 2007
Subcellular localisation and induction of NADH-sensitive acetyl-CoA hydrolase and propionyl-CoA hydrolase activities in rat liver under lipogenic conditions after treatment with sulfur-substituted fatty acids journal March 1995
Kinetic Analysis of the 4-Methylideneimidazole-5-one-Containing Tyrosine Aminomutase in Enediyne Antitumor Antibiotic C-1027 Biosynthesis † journal November 2003
Reactivity of Lactones and GHB Formation journal January 2005
Feasibility of acrylic acid production by fermentation journal February 2005
Designs for a broad substrate specificity keto acid dehydrogenase journal September 1990
Enhanced production of succinic acid by metabolically engineeredEscherichia coli with amplified activities of malic enzyme and fumarase journal August 2004
Properties of the reversible nonoxidative vanillate / 4-hydroxybenzoate decarboxylase from Bacillus subtilis journal January 2008
A general method for greatly improving the affinity of antibodies by using combinatorial libraries journal June 2005
Fumarate metabolism and the microaerophily of Campylobacter species journal September 1999
Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme. journal January 1992
Formation of Lactyl-Coenzyme A and Pyruvyl-Coenzyme A from Lactic Acid by Escherichia coli journal January 1965
Cloning of aldB, which encodes alpha-acetolactate decarboxylase, an exoenzyme from Bacillus brevis. journal January 1990
Mechanism of Transfer of the Methyl Group from (6 S )-Methyltetrahydrofolate to the Corrinoid/Iron−Sulfur Protein Catalyzed by the Methyltransferase from Clostridium thermoaceticum :  A Key Step in the Wood−Ljungdahl Pathway of Acetyl-CoA Synthesis † journal May 1999
Studies on the Metabolism of Unsaturated Fatty Acids. XIV.1 Purification and Properties of NADPH-Dependent trans-2-Enoyl-CoA Reductase of Escherichia coli K-12 journal May 1984
Highly Selective Diels-Alder Reactions of Directly Connected Enyne Dienophiles journal January 2007
Use of genome-scale microbial models for metabolic engineering journal February 2004
Mammalian Wax Biosynthesis: I. Identification Of Two Fatty Acyl-Coenzyme A Reductases With Different Substrate Specificities And Tissue Distributions journal June 2004
Existence and Properties of Two Malic Enzymes in Escherichia coliEspecially of NAD-linked Enzyme journal September 1969
Design of a specific phenyllactate dehydrogenase by peptide loop exchange on the Bacillus stearothermophilus lactate dehydrogenase framework journal September 1992
Purification and Characterization of the Oxygen-Sensitive 4-Hydroxybutanoate Dehydrogenase from Clostridium kluyveri journal April 1995
Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock journal December 2003
Pyruvate Dehydrogenase, Substrate Specificity and Product Inhibition journal April 1969
Intracellular sorting of alcohol dehydrogenase isoenzymes in yeast: a cytosolic location reflects absence of an amino-terminal targeting sequence for the mitochondrion. journal January 1986
Propanol as an end product of threonine fermentation journal September 2004
Increasing the Acetyl-CoA Pool in the Presence of Overexpressed Phosphoenolpyruvate Carboxylase or Pyruvate Carboxylase Enhances Succinate Production in Escherichia coli journal October 2004
Preliminary X-ray crystallographic analysis of ornithine acetyltransferase (Rv1653) from Mycobacterium tuberculosis journal January 2009
Characterization and physiological roles of membrane-bound hydrogenase isoenzymes from Salmonella typhimurium. journal January 1986
Aspartate Dehydrogenase, a Novel Enzyme Identified from Structural and Functional Studies of TM1643 journal December 2002
Metabolic engineering of Aeromonas hydrophila for the enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) journal June 2005
Fructose-6-phosphate Aldolase Is a Novel Class I Aldolase from Escherichia coli and Is Related to a Novel Group of Bacterial Transaldolases journal December 2000
Molecular properties of the lys1 + gene and the regulation of ?-aminoadipate reductase in Schizosaccharomyces pombe journal July 1995
Cloning and characterization of the gamma-glutamyl phosphate reductase gene of Campylobacter jejuni journal July 1993
GriC and GriD Constitute a Carboxylic Acid Reductase Involved in Grixazone Biosynthesis in Streptomyces griseus journal June 2007
Asymmetric Transformation of Enones with Synechococcus sp. PCC 7942 journal December 2004
Thermodynamics of reactions catalyzed by anthranilate synthase journal February 2000
2-Oxoacid:Ferredoxin Oxidoreductase from the Thermoacidophilic Archaeon, Sulfolobus sp. Strain 7 journal September 1996
A cofactor-dependent phosphoglycerate mutase homolog from Bacillus stearothermophilus is actually a broad specificity phosphatase journal September 2001
A novel lysine 2,3-aminomutase encoded by the yodO gene of Bacillus subtilis: characterization and the observation of organic radical intermediates journal June 2000
Rate Enhancement by Ethylene in the Ru-Catalyzed Ring-Closing Metathesis of Enynes: Evidence for an “Ene-then-Yne” Pathway that Diverts through a Second Catalytic Cycle journal November 2005
Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production journal September 1999
The Biofine Process– Production of Levulinic Acid, Furfural, and Formic Acid from Lignocellulosic Feedstocks book December 2005
Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets journal April 2005
Glutamate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: molecular characterization and phylogenetic implications journal February 1997
Stability of broad host range cloning vectors in the phototrophic bacterium Rhodospirillum rubrum journal August 1992
Nucleotide sequence of the fadA and fadB genes from Escherichia coli journal January 1990
Combining computational and experimental screening for rapid optimization of protein properties journal November 2002
A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants journal May 1998
Isolation, Overexpression, and Biochemical Characterization of the Two Isoforms of Glutamic Acid Decarboxylase fromEscherichia coli journal December 1996
In Vivo Analysis of the Mechanisms for Oxidation of Cytosolic NADH by Saccharomyces cerevisiae Mitochondria journal May 2000
Rearrangement of l -2-Hydroxyglutarate to l - threo -3-Methylmalate Catalyzed by Adenosylcobalamin-Dependent Glutamate Mutase † journal August 2000
Versatility of the mitochondrial protein import machinery journal May 2001
Regulation of the NADH and NADPH-ferredoxin oxidoreductases in Clostridia of the butyric group journal February 1976
A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6 journal December 2003
Aspartate-beta-Semialdehyde Dehydrogenase from Escherichia coli. Purification and General Properties journal February 1980
Characterization and Sequence Analysis of the Human Ornithine Decarboxylase Gene journal November 1989
Molecular characterization of lysine 6-dehydrogenase from Achromobacter denitrificans journal November 2008
Identification of the Amino Acid Residues Conferring Substrate Specificity upon Selenomonas ruminantium Lysine Decarboxylase journal January 1999
Transcriptional Organization of Genes for Protocatechuate and Quinate Degradation from Acinetobacter sp. Strain ADP1 journal February 2005
Crystal structure of the Acidaminococcus fermentans 2-hydroxyglutaryl-CoA dehydratase component A journal March 2001
Cloning and Characterization of the Gene Encoding Lipoamide Dehydrogenase in Saccharomyces Cerevisiae journal April 1987
Effect of Different Carbon Sources on the Production of Succinic Acid Using Metabolically Engineered Escherichia coli journal April 2007
Ornithine degradation in Clostridium sticklandii. Pyridoxal phosphate and coenzyme A dependent thiolytic cleavage of 2-amino-4-ketopentanoate to alanine and acetyl coenzyme A journal July 1974
Regulatory on/off minimization of metabolic flux changes after genetic perturbations journal May 2005
Engineered Synthetic Pathway for Isopropanol Production in Escherichia coli journal October 2007
Glutamate dehydrogenase of Halobacterium salinarum : evidence that the gene sequence currently assigned to the NADP + -dependent enzyme is in fact that of the NAD + -dependent glutamate dehydrogenase journal May 2002
Biosynthesis of pimeloyl-CoA, a biotin precursor in Escherichia coli, follows a modified fatty acid synthesis pathway: 13C-labeling studies journal March 1994
Enzymes involved in acetoacetate formation in various bovine tissues journal May 1970
PIO study on 1,3-butanediol dehydration over CeO2 (111) surface journal April 2005
Metabolic Engineering of Escherichia coli: Increase of NADH Availability by Overexpressing an NAD+-Dependent Formate Dehydrogenase journal July 2002
Options for biochemical production of 4-hydroxybutyrate and its lactone as a substitute for petrochemical production journal January 2008
Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes journal January 2004
Colistin Nephrotoxicity: Report of a case with Light and Electron Microscopic Studies1 journal February 1969
Substrate Selectivity and Biochemical Properties of 4-Hydroxy-2-Keto-Pentanoic Acid Aldolase from Escherichia coli journal October 1998
The primary structure of branched-chain alpha-oxo acid dehydrogenase from Bacillus subtilis and its similarity to other alpha-oxo acid dehydrogenases journal May 1993
Construction of Environmental DNA Libraries inEscherichia coli and Screening for the Presence of Genes Conferring Utilization of 4-Hydroxybutyrate journal September 1999
The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis: Co-ordinated feedback regulation journal March 2003
Enoate Reductases of Clostridia: CLONING, SEQUENCING, AND EXPRESSION journal November 2000
6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes: Gene probe for ring-opening hydrolases journal February 2008
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica journal July 1999
Propanediol utilization genes (pdu) of Salmonella typhimurium: three genes for the propanediol dehydratase. journal November 1997
Purification and properties of two oxidoreductases catalyzing the enantioselective reduction of diacetyl and other diketones from baker's yeast journal February 1990
Identification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both l-ornithine and l-lysine journal December 2001
Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization journal October 2003
Purification and properties of membrane-bound hydrogenase isoenzyme 1 from anaerobically grown Escherichia coli K12 journal April 1986
A cluster of bacterial genes for anaerobic benzene ring biodegradation journal June 1997
Analysis of Oxidation Sensitivity of Maleate cis-trans Isomerase from Serratia marcescens journal January 2000
Bioconversion of propionic, valeric, and 4-hydroxybutyric acids into the corresponding alcohols byClostridium acetobutylicum NRRL 527 journal July 1986
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products journal May 2000
Genome Sequence and Comparative Analysis of the Solvent-Producing Bacterium Clostridium acetobutylicum journal August 2001
Metabolism of poly-β-hydroxybutyrate. II. Enzymic synthesis of D-(-)-β-hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum journal July 1969
NAD(P)H regeneration is the key for heterolactic fermentation of hexoses in Oenococcus oeni journal January 2002
Molecular and Biochemical Characterization of 2-Hydroxyisoflavanone Dehydratase. Involvement of Carboxylesterase-Like Proteins in Leguminous Isoflavone Biosynthesis journal February 2005
The pyruvate formate lyase family: sequences, structures and activation journal June 2004
Monoterpene double-bond reductases of the (−)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (−)-isopiperitenone reductase and (+)-pulegone reductase of peppermint journal October 2003
Putrescine N-acetyltransferase in Onchocerca volvulus and Ascaris suum, an enzyme which is involved in polyamine degradation and release of N-acetylputrescine journal January 1990
Life in Hot Carbon Monoxide: The Complete Genome Sequence of Carboxydothermus hydrogenoformans Z-2901 journal January 2005
The YbgC protein encoded by the ybgC gene of the tol-pal gene cluster of Haemophilus influenzae catalyzes acyl-coenzyme A thioester hydrolysis journal March 2002
Structure of Acetylglutamate Kinase, a Key Enzyme for Arginine Biosynthesis and a Prototype for the Amino Acid Kinase Enzyme Family, during Catalysis journal March 2002
Purification and characterization of maleylacetate reductase from Alcaligenes eutrophus JMP134(pJP4). journal January 1993
Molecular characterization of two Clostridium acetobutylicum ATCC 824 butanol dehydrogenase isozyme genes. journal January 1992
Metabolism of Benzoate, Cyclohex-1-ene Carboxylate, and Cyclohexane Carboxylate by "Syntrophus aciditrophicus" Strain SB in Syntrophic Association with H2-Using Microorganisms journal April 2001
Putrescine Breakdown in the Yeast Candida boidinii: Subcellular Location of Some of the Enzymes Involved and Properties of Two Acetamidoaldehyde Dehydrogenases journal September 1987
Purification of a branched-chain keto acid dehydrogenase from Pseudomonas putida. journal January 1981
The Structures of l-Rhamnose Isomerase from Pseudomonas stutzeri in Complexes with l-Rhamnose and d-Allose Provide Insights into Broad Substrate Specificity journal February 2007
Effect of l-glutamate on 2-oxoglutarate decarboxylase in Euglena gracilis journal March 1992
Identification of a Novel Pyridoxal 5‘-Phosphate Binding Site in Adenosylcobalamin-Dependent Lysine 5,6-Aminomutase from Porphyromonas gingivalis † journal July 2002
Regulation of branched-chain amino acid biosynthesis by α-acetolactate decarboxylase in Streptococcus thermophilus journal June 2003
Expression of Galactose Permease and Pyruvate Carboxylase in Escherichia coli ptsG Mutant Increases the Growth Rate and Succinate Yield under Anaerobic Conditions journal January 2006
Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. journal January 1990
4-Acetamidobutyrate Deacetylase in the Yeast Candida boidinii Grown on Putrescine or Spermidine as Sole Nitrogen Source and Its Probable Role in Polyamine Catabolism journal January 1986
PCR based gene engineering of the Vibrio harveyi lux operon and the Escherichia coli trp operon provides for biochemically functional native and fused gene products journal April 1991
Thermostable NADP+-Dependent Medium-Chain Alcohol Dehydrogenase from Acinetobacter sp. Strain M-1: Purification and Characterization and Gene Expression inEscherichia coli journal December 2000
d- and l-Isoleucine Metabolism and Regulation of Their Pathways in Pseudomonas putida journal January 1974
Cloning of the lys A gene from Mycobacterium tuberculosis journal February 1993
Phylogenetic Diversity and the Structural Basis of Substrate Specificity in the β/α-Barrel Fold Basic Amino Acid Decarboxylases journal July 2007
Reciprocal Isomerization of Butyrate and Isobutyrate by the Strictly Anaerobic Bacterium Strain WoG13 and Methanogenic Isobutyrate Degradation by a Defined Triculture journal January 1992
Conversion of glutaconate CoA-transferase from Acidaminococcus fermentans into an acyl-CoA hydrolase by site-directed mutagenesis journal March 1997
Succinic Semialdehyde Dehydrogenases of Escherichia coli. Their Role in the Degradation of p-Hydroxyphenylacetate and gamma-Aminobutyrate journal January 1981
Pyruvate Decarboxylase Catalyzes Decarboxylation of Branched-Chain 2-Oxo Acids but Is Not Essential for Fusel Alcohol Production by Saccharomyces cerevisiae journal April 1998
[27] Random mutagenesis of protein sequences using oligonucleotide cassettes book January 1991
The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features journal January 2008
Molecular Characterization and Transcriptional Analysis of adhE2, the Gene Encoding the NADH-Dependent Aldehyde/Alcohol Dehydrogenase Responsible for Butanol Production in Alcohologenic Cultures of Clostridium acetobutylicum ATCC 824 journal February 2002
argE -Encoded N -Acetyl- l -Ornithine Deacetylase from Escherichia c oli Contains a Dinuclear Metalloactive Site journal October 2005
Genetic and proteomic analyses of CO utilization by Methanosarcina acetivorans journal June 2007
Wax Ester Production from n-Alkanes by Acinetobacter sp. Strain M-1: Ultrastructure of Cellular Inclusions and Role of Acyl Coenzyme A Reductase journal March 2002
Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation journal April 2007
A General Model for Selectivity in Olefin Cross Metathesis journal September 2003
Methylcobalamin:Coenzyme M Methyltransferase Isoenzymes MtaA and MtbA from Methanosarcina barkeri. Cloning, Sequencing and Differential Transcription of the Encoding Genes, and Functional Overexpression of the mtaA Gene in Escherichia coli journal February 1996
Pyruvate decarboxylase: a key enzyme for the oxidative metabolism of lactic acid by Acetobacter pasteurianus journal December 2001
Cloning and Overexpression of the 3-Hydroxyisobutyrate Dehydrogenase Gene from Pseudomonas putida E23 journal January 2003
Gratuitous repression of avtA in Escherichia coli and Salmonella typhimurium. journal January 1984
Redistribution of Metabolic Fluxes in the Central Aerobic Metabolic Pathway of E. coli Mutant Strains with Deletion of the ackA-pta and poxB Pathways for the Synthesis of Isoamyl Acetate journal January 2005
Error-prone rolling circle amplification: the simplest random mutagenesis protocol journal December 2006
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding journal May 1976
Production and Characterization of Bifunctional Enzymes. Domain Swapping To Produce New Bifunctional Enzymes in the Aspartate Pathway † journal March 2002
Structure, Function, and Mechanism of the Phenylacetate Pathway Hot Dog-fold Thioesterase PaaI journal February 2006
Purification and characterization of the NADH-dependent butanol dehydrogenase from Clostridium acetobutylicum (ATCC 824) journal September 1989
The discovery of four distinct glutamate dehydrogenase genes in a strain of Halobacterium salinarum journal April 2005
Expression of an aromatic-dependent decarboxylase which provides growth-essential CO2 equivalents for the acetogenic (Wood) pathway of Clostridium thermoaceticum. journal January 1990
Poly-3-Hydroxybutyrate Degradation in Rhizobium (Sinorhizobium) meliloti: Isolation and Characterization of a Gene Encoding 3-Hydroxybutyrate Dehydrogenase journal February 1999
Acetylputrescine deacetylase from Micrococcus luteus K-11 journal June 1986
Kinetics and Specificity of Human Liver Aldehyde Dehydrogenases toward Aliphatic, Aromatic, and Fused Polycyclic Aldehydes † journal January 1996
Butanol fermentation research: upstream and downstream manipulations journal January 2004
Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism journal February 1993
Activation of (R)-2-hydroxyglutaryl-CoA Dehydratase from Acidaminococcus fermentans journal June 1995
Acetylation: a regulatory modification to rival phosphorylation? journal March 2000
The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis journal March 1999
One of the Fumarate Reductase Isoenzymes fromSaccharomyces cerevisiaeIs Encoded by theOSM1Gene journal April 1998
Crystallization and some properties of acetylpolyamine amidohydrolase from Mycoplana bullata journal December 1988
Random-priming in vitro recombination: An effective tool for directed evolution journal January 1998
Enzymology of butyrate formation by Butyrivibrio fibrisolvens. journal January 1979
Maleylacetate reductase of Pseudomonas sp. strain B13: specificity of substrate conversion and halide elimination. journal January 1995
The catalytic cycle of  -lactam synthetase observed by x-ray crystallographic snapshots journal October 2002
The crystal structure of chorismate lyase shows a new fold and a tightly retained product journal January 2001
Subcellular localization and tissue distribution of α-ketoadipate reduction and oxidation in the rat journal July 1977
Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum journal April 2001
Purification of a Jojoba Embryo Wax Synthase, Cloning of its cDNA, and Production of High Levels of Wax in Seeds of Transgenic Arabidopsis journal March 2000
Cloning and expression of the gene cluster encoding key proteins involved in acetyl-CoA synthesis in Clostridium thermoaceticum: CO dehydrogenase, the corrinoid/Fe-S protein, and methyltransferase. journal January 1989
Cloning and expression of Clostridium acetobutylicum phosphotransbutyrylase and butyrate kinase genes in Escherichia coli. journal January 1988
Biochemical thermodynamics journal July 1994
Generation of Phenylpropanoid Pathway-Derived Volatiles in Transgenic Plants: Rose Alcohol Acetyltransferase Produces Phenylethyl Acetate and Benzyl Acetate in Petunia Flowers journal March 2006
Functional analysis of the methylmalonyl-CoA epimerase from Caenorhabditis elegans: Methylmalonyl-CoA epimerase from C. elegans journal March 2005
Enzyme genomics: Application of general enzymatic screens to discover new enzymes journal April 2005
Biosynthesis of Poly(3-hydroxybutyrate- co-3-hydroxyalkanoates) by Metabolically Engineered Escherichia coli Strains journal January 2004
Cloning, Sequencing, Heterologous Expression, Purification, and Characterization of Adenosylcobalamin-dependentd-Ornithine Aminomutase from Clostridium sticklandii journal September 2001
Purification and Characterization of Two Muconate Cycloisomerase Isozymes from Aniline-assimilating Frateuria Species ANA-18 journal January 1998
Purification and properties of 4-aminobutyrate 2-ketoglutarate aminotransferase from pig liver journal February 1978
Comparison of fumaric acid production by Rhizopus oryzae using different neutralizing agents journal September 2002
Functional Analysis and Regulation of the Divergent spuABCDEFGH-spuI Operons for Polyamine Uptake and Utilization in Pseudomonas aeruginosa PAO1 journal July 2002
Fumaric acid overproduction in yeast mutants deficient in fumarase journal March 1992
Improving the carboligase activity of benzoylformate decarboxylase from Pseudomonas putida by a combination of directed evolution and site-directed mutagenesis journal July 2002
High Copy Number Plasmids Compatible with Commonly Used Cloning Vectors journal March 2000
Threonine-sensitive aspartokinase-homoserine dehydrogenase complex amino acid compositions, molecular weight, and subunit composition of the complex journal February 1972
Genetic analysis of Carboxydothermus hydrogenoformans carbon monoxide dehydrogenase genes cooF and cooS journal October 2000
Structure of Aspartate-β-semialdehyde Dehydrogenase from Escherichia coli, a Key Enzyme in the Aspartate Family of Amino Acid Biosynthesis journal June 1999
Purification of a Jojoba Embryo Fatty Acyl-Coenzyme A Reductase and Expression of Its cDNA in High Erucic Acid Rapeseed journal March 2000
Enzyme reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species journal August 1989
Characterization of the major citrate synthase of Bacillus subtilis. journal January 1996
Effect of carbon sources differing in oxidation state and transport route on succinate production in metabolically engineered Escherichia coli journal March 2005
A pH-regulated promoter for the expression of recombinant proteins inEscherichia coli journal March 1992
Sodium ion-translocating decarboxylases journal May 2001
[42] The arom multifunctional enzyme from neurospora crassa book January 1987
Mossbauer Study of 4-Hydroxybutyryl-CoA Dehydratase Probing the Role of an Iron-Sulfur Cluster in an Overall Non-Redox Reaction journal September 1997
Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth journal November 2002
The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum) journal July 2008
Folding of Fumarase during Mitochondrial Import Determines its Dual Targeting in Yeast journal September 2003
Purification and properties of an iron-sulfur and FAD-containing 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase from Clostridium aminobutyricum journal July 1993
Preparation and reactivity of several alkylidene complexes of the type W(CHR')(N-2,6-C6H3-iso-Pr2)(OR)2 and related tungstacyclobutane complexes. Controlling metathesis activity through the choice of alkoxide ligand journal March 1988
A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria journal March 2007
Purification and Characterization of Ornithine Acetyltransferase from Saccharomyces cerevisiae journal March 1995
Lysine decarboxylase of Vibrio parahaemolyticus: kinetics of transcription and role in acid resistance journal May 2008
l-Lysine biosynthetic pathway of Methylophilus methylotrophus and construction of an l-lysine producer journal July 2006
Gene expression and characterization of two 2-oxoacid:ferredoxin oxidoreductases from Aeropyrum pernix K1 journal March 2005
l-Threonine Deaminase of Rhodospirillum rubrum. Purification and Characterization journal August 1971
Redefining chemical manufacture journal March 2005
Purification of acetoacetate decarboxylase from Clostridium acetobutylicum ATCC 824 and cloning of the acetoacetate decarboxylase gene in Escherichia coli. journal January 1990
Isolation, crystallization and preliminary X-ray analysis of a methanol-induced corrinoid protein from Moorella thermoacetica journal April 2005
Cloning and characterization ofMannheimia succiniciproducens MBEL55E phosphoenolpyruvate carboxykinase (pckA) gene journal April 2002
Aerobic Dissimilation of Glucose by Heterolactic Bacteria journal January 1972
Carbon metabolism regulates expression of the pfl (pyruvate formate-lyase) gene in Escherichia coli. journal January 1991
Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase–aldehyde dehydrogenase (acylating) from Pseudomonas  sp. strain CF600 journal April 2001
Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coli γ-Aminobutyrate Aminotransferase † journal March 2005
Purification and Characterization of a Thermostable Class II Fumarase fromThermus thermophilus journal July 1998
On the Activity and Regulation of Anaplerotic and Gluconeogenetic Enzymes during the Growth Process of Baker's Yeast. The Biphasic Growth journal March 1975
Discovering Nature's Diverse Pathways to Vitamin B 12 :  A 35-Year Odyssey journal April 2003
Soluble fumarate reductase isoenzymes from Saccharomyces cerevisiae are required for anaerobic growth journal August 1998
Cloning, Sequencing, and Expression of the Pyruvate Carboxylase Gene in Lactococcus lactis subsp. lactis C2 journal March 2000
Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. journal January 1993
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans journal December 2003
Anaerobic growth of Methanosarcina acetivorans C2A on carbon monoxide: An unusual way of life for a methanogenic archaeon journal November 2004
A multifunctional fermentative alcohol dehydrogenase from the strict aerobe Alcaligenes eutrophus: purification and properties journal June 1984
Metabolic flux elucidation for large-scale models using 13C labeled isotopes journal September 2007
Glutaconate CoA-Transferase from Acidaminococcus fermentans journal August 1981
Structural and biochemical characterization of the Escherichia coli argE gene product. journal January 1992
On the occurrence of enoate reductase and 2-oxo-carboxylate reductase in clostridia and some observations on the amino acid fermentation by Peptostreptococcus anaerobius journal January 1983
(R)-Lactyl-CoA dehydratase from Clostridium propionicum: Stereochemistry of the dehtdratio of (R)-2-hydroxybutyryl-CoA to crotonyl-CoA journal June 1992
Rapid generation of incremental truncation libraries for protein engineering using alpha-phosphothioate nucleotides journal February 2001
ato Operon: a Highly Inducible System for Acetoacetate and Butyrate Degradation in Escherichia coli journal September 1972
Expression of the second lysine decarboxylase gene of Escherichia coli journal March 1998
Lysine-2,3-Aminomutase and β-Lysine Acetyltransferase Genes of Methanogenic Archaea Are Salt Induced and Are Essential for the Biosynthesis of Nε-Acetyl-β-Lysine and Growth at High Salinity journal October 2003
Catalytic Upgrading of Fermentation-Derived Organic Acids journal October 1999
Energy Conservation via Electron-Transferring Flavoprotein in Anaerobic Bacteria journal November 2007
A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of Escherichia coli journal August 1990
Sodium Ion Pumps and Hydrogen Production in Glutamate Fermenting Anaerobic Bacteria
  • Boiangiu, Clara D.; Jayamani, Elamparithi; Brügel, Daniela
  • Journal of Molecular Microbiology and Biotechnology, Vol. 10, Issue 2-4 https://doi.org/10.1159/000091558
journal January 2005
Proximity of reactive cysteine residue and flavin in Escherichia coli pyruvate oxidase as estimated by fluorescence energy transfer journal August 1982
Ethanol and acetate synthesis from waste gas using batch culture of Clostridium ljungdahlii journal January 2006
Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control journal December 2001
Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution journal February 2004
Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution journal July 2005
Cloning and characterization of a human orthologue of testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t) cDNA journal January 2002
Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase journal March 2006
A novel fermentation pathway in anEscherichia coli mutant producing succinic acid, acetic acid, and ethanol journal March 1998
Coenzyme M methylase activity of the 480-kilodalton corrinoid protein from Methanosarcina barkeri. journal January 1996
Mechanism of the Reaction Catalyzed by Acetoacetate Decarboxylase. Importance of Lysine 116 in Determining the p K a of Active-Site Lysine 115 † journal January 1996
Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening journal April 1997
Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli. journal January 1991
Genome-scale microbial in silico models: the constraints-based approach journal April 2003
A wide host-range metagenomic library from a waste water treatment plant yields a novel alcohol/aldehyde dehydrogenase: Metagenomic cloning of alcohol dehydrogenase journal August 2005
Probing the performance limits of theEscherichia coli metabolic network subject to gene additions or deletions journal January 2001
Studies on the Metabolism of Unsaturated Fatty Acids. IX. Stereochemical Studies of the Reaction Catalyzed by trans-2-Enoyl-Coenzyme A Reductase of Escherichia coli1 journal October 1982
Expression of hepatitis B surface antigen in Saccharomyces cerevisiae utilizing glyceraldeyhyde-3-phosphate dehydrogenase promoter of Pichia pastoris journal November 2006
Effect of Modulated Glucose Uptake on High-Level Recombinant Protein Production in a Dense Escherichia coli Culture journal November 1994
Anaerobic metabolism of cyclohexanol by denitrifying bacteria journal August 1988
Purification and characterization of the alcohol dehydrogenase with a broad substrate specificity originated from 2-phenylethanol-assimilating Brevibacterium sp. KU 1309 journal September 2005
Cloning and sequencing of the genes of 2-hydoxyglutaryl-CoA dehydratase from Acidaminococcus fermentans journal May 1989
Characterization and sequence of the Escherichia coli panBCD gene cluster journal October 1996
Regulation of succinate dehydrogenase (sdhCDAB) operon expression in Escherichia coli in response to carbon supply and anaerobiosis: role of ArcA and Fnr journal February 1995
Immunological comparison of microbial TPP-dependent non-oxidative α-keto acid decarboxylases journal March 1986
Structural and functional organization of the animal fatty acid synthase journal July 2003
Importance of redox balance on the production of succinic acid by metabolically engineered Escherichia coli journal March 2002
Enzymology of the Wood-Ljungdahl Pathway of Acetogenesis journal March 2008
Ethanol tolerance and membrane fatty acid adaptation in adh multiple and null mutants of Kluyveromyces lactis journal November 2000
Cross-metathesis of dimethyl maleate and ethylene catalyzed by second generation ruthenium carbene complexes: B3LYP and MPW1K comparison study journal December 2006
Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently journal November 2002
Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation journal December 2008
Development of a novel continuous culture device for experimental evolution of bacterial populations journal September 2007
Effect of Overexpression of Actinobacillus succinogenes Phosphoenolpyruvate Carboxykinase on Succinate Production in Escherichia coli journal February 2004
The Billion-Ton Biofuels Vision journal June 2006
Anaerobic metabolism of aromatic compounds via the benzoyl-CoA pathway journal December 1998
Transmembrane Transport of Cobalamin in Prokaryotic and Eukaryotic Cells journal June 1981
Escherichia coli l-aspartate-α-decarboxylase: preprotein processing and observation of reaction intermediates by electrospray mass spectrometry journal May 1997
Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of Escherichia coli reside on a polymeric protein particle encoded by adhE journal April 1991
Crystallization of the NADP+-dependent Glutamate Dehydrogenase from Escherichia coli journal December 1993
Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis journal August 1999
Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp journal January 1985
Degenerate oligonucleotide gene shuffling (DOGS): a method for enhancing the frequency of recombination with family shuffling journal June 2001
The Enzymatic Synthesis of β-Alanyl Coenzyme a journal November 1955
Purification and properties of α-ketoadipate reductase, a newly discovered enzyme from human placenta journal October 1976
Expression of the Corynebacterium glutamicum panD Gene Encoding l-Aspartate-α-Decarboxylase Leads to Pantothenate Overproduction in Escherichia coli journal April 1999
[43] Butyryl-CoA dehydrogenase from Megasphaera elsdenii book January 1981
Actinobacillus succinogenes sp. nov., a novel succinic-acid-producing strain from the bovine rumen journal January 1999
The non-oxidative decarboxylation ofp-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid byKlebsiella aerogenes (Aerobacter aerogenes) journal December 1969
Involvement of branched-chain amino acid aminotransferases in the production of fusel alcohols during fermentation in yeast journal April 2001
On the occurrence of enzymes of ketone-body metabolism in human adipose tissue journal March 1976
A Cyclometalated Aryloxy(chloro)neopentylidenetungsten Complex: A Highly Active and Stereoselective Catalyst for the Metathesis of cis- and trans-2-Pentene, Norbornene, 1-Methyl-norbornene, and Ethyl Oleate journal May 1992
Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop journal April 2004
Enzymatic Decarboxylation of the Aminobenzoates 1 journal February 1957
Fermentation of biomass-generated producer gas to ethanol journal January 2004
Crystal Structure of Yeast Peroxisomal Multifunctional Enzyme: Structural Basis for Substrate Specificity of (3R)-hydroxyacyl-CoA Dehydrogenase Units journal May 2006
Selective synthesis of isobutanol by means of the Guerbet reaction journal June 2002
Active oligomeric states of pyruvate decarboxylase and their functional characterization journal March 2001
The Diels—Alder Reaction with α,β,γ,δ-Unsaturated Acids journal September 1950
Benzene-Free Synthesis of Adipic Acid journal April 2002
Increased Alcohol Acetyltransferase Activity by Inositol Limitation in Saccharomyces cerevisiae in Sake Mash journal January 2003
Purification and properties of 3-hydroxybutyryl-coenzyme A dehydrogenase from Clostridium beijerinckii ("Clostridium butylicum") NRRL B593. journal January 1992
Mitochondrial trans-2-Enoyl-CoA Reductase of Wax Ester Fermentation from Euglena gracilis Defines a New Family of Enzymes Involved in Lipid Synthesis journal November 2004
Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids journal March 2007
Molecular Cloning, Sequencing and Characterization of the Genes for Adenosylcobalamin-dependent Diol Dehydratase of Klebsiella pneumoniae journal January 1998
Substrate specificity of the 3-methylaspartate ammonia-lyase reaction: observation of differential relative reaction rates for substrate-product pairs journal April 1988
Role of transmembrane segment M8 in the biogenesis and function of yeast plasma-membrane H+-ATPase journal October 2007
Molecular characterization of the 1,3-propanediol (1,3-PD) operon of Clostridium butyricum journal April 2003
Site-directed mutational analysis of the novel catalytic domains of α-aminoadipate reductase (Lys2p) from Candida albicans journal March 2003
Two outer membrane transport systems for vitamin B12 in Salmonella typhimurium. journal January 1989
The Refined X-ray Structure of Muconate Lactonizing Enzyme fromPseudomonas putidaPRS2000 at 1.85 Å Resolution journal December 1995
Monofunctional biosynthetic peptidoglycan transglycosylases journal February 1996
Purification and partial amino acid sequence of the cyanogen bromide fragments of muconolactone isomerase from Pseudomonas putida journal September 1977
Structural and Functional Evidence for Bacillus subtilis PaiA as a Novel N 1 -Spermidine/Spermine Acetyltransferase journal October 2005
[17] Assay of leucine 2,3-aminomutase book January 1988
Genetic Characterization of the Resorcinol Catabolic Pathway in Corynebacterium glutamicum journal September 2006
Systems Properties of the Haemophilus influenzae Rd Metabolic Genotype journal June 1999
Cloning and expression of the gene for the vitamin B12 receptor protein in the outer membrane of Escherichia coli. journal January 1985
Global analysis of protein localization in budding yeast journal October 2003
Reaction Mechanism of the Heterotetrameric (α 2 β 2 ) E1 Component of 2-Oxo Acid Dehydrogenase Multienzyme Complexes † journal June 2003
Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine journal October 2003
l-2-Hydroxyglutarate dehydrogenase: identification of a novel enzyme activity in rat and human liver. Implications for l-2-hydroxyglutaric acidemia journal November 1993
Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii. journal January 1997
“Designer” Biodiesel: Optimizing Fatty Ester Composition to Improve Fuel Properties † journal March 2008
Sequence and arrangement of two genes of the butyrate-synthesis pathway of Clostridium acetobutylicum ATCC 824 journal November 1993
Spo0A directly controls the switch from acid to solvent production in solvent-forming clostridia journal September 2000
Crystal structure of the truncated cubic core component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex journal July 1998
Propionate CoA-transferase from Clostridium propionicum: Cloning of the gene and identification of glutamate 324 at the active site journal January 2002
Molecular analysis of the anaerobic succinate degradation pathway in Clostridium kluyveri. journal January 1996
Occurrence of l-Lysine ε-Dehydrogenase in Agrobacterium tumefaciens journal January 1982
d-3-Hydroxybutyrate Dehydrogenase from Pseudomonas fragi: Molecular Cloning of the Enzyme Gene and Crystal Structure of the Enzyme journal January 2006
Purification and properties of a novel enzyme, L-α-amino-ϵ-caprolactamase from Cryptococcus laurentii journal May 1978
Improved conversion of fumarate to succinate by Escherichia coli strains amplified for fumarate reductase. journal January 1983
Bacterial lactate dehydrogenases. journal January 1980
Expression and Purification of Aspartate β-Semialdehyde Dehydrogenase from Infectious Microorganisms journal June 2002
Engineering Yeast Transcription Machinery for Improved Ethanol Tolerance and Production journal December 2006
Physiology of the thermophilic acetogen Moorella thermoacetica journal December 2004
Gene cloning, purification, and characterization of thermostable and halophilic leucine dehydrogenase from a halophilic thermophile, Bacillus licheniformis TSN9 journal December 1995
Genome-Based Metabolic Engineering of Mannheimia succiniciproducens for Succinic Acid Production journal March 2006
Assembly and Protection of the Radical Enzyme, Methylmalonyl-CoA Mutase, by Its Chaperone † journal August 2006
Genome-scale models of microbial cells: evaluating the consequences of constraints journal November 2004
Molecular cloning and functional expression of rat liver cytosolic acetyl-CoA hydrolase: Expression of rat cytosolic acetyl-CoA hydrolase journal May 2001
Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv journal April 2005
Titanium metallacarbene-metallacyclobutane reactions: stepwise metathesis journal September 1980
Salmonella typhimurium cobalamin (vitamin B12) biosynthetic genes: functional studies in S. typhimurium and Escherichia coli. journal January 1996
Heterologous expression of the Saccharomyces cerevisiae alcohol acetyltransferase genes in Clostridium acetobutylicum and Escherichia coli for the production of isoamyl acetate journal July 2003
Directed evolution: selecting today's biocatalysts journal June 2005
Structure of free fumarase C from Escherichia coli journal September 2005
Enoyl-CoA hydratase journal January 2003
Chaperonin GroESL mediates the protein folding of human liver mitochondrial aldehyde dehydrogenase in Escherichia coli journal October 2002
Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding ?-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB journal March 1989
Primary structure of the monomer of the 12S subunit of transcarboxylase as deduced from DNA and characterization of the product expressed in Escherichia coli. journal January 1993
Cloning and expression of Acinetobacter calcoaceticus catBCDE genes in Pseudomonas putida and Escherichia coli. journal January 1986
Engineering Escherichia coli for Fermentative Dihydrogen Production: Potential Role of NADH-Ferredoxin Oxidoreductase from the Hydrogenosome of Anaerobic Protozoa journal January 2009
Contrasting patterns of evolutionary divergence within the Acinetobacter calcoaceticus pca operon journal August 1994
Purification and characterisation of a plasminogen-binding protein from Haemophilus influenzae. Sequence determination reveals identity with aspartase journal March 1997
The Structural Biology of type ii Fatty acid Biosynthesis journal June 2005
Evidence That NiNi Acetyl-CoA Synthase Is Active and That the CuNi Enzyme Is Not † journal April 2004
A gene duplication led to specialized γ-aminobutyrate and β-alanine aminotransferase in yeast: Origin of yeast aminotransferases journal March 2007
Identification of the Human Methylmalonyl-CoA Racemase Gene Based on the Analysis of Prokaryotic Gene Arrangements: IMPLICATIONS FOR DECODING THE HUMAN GENOME journal July 2001
Genetic Analysis of the Methanol- and Methylamine-Specific Methyltransferase 2 Genes of Methanosarcina acetivorans C2A journal March 2008
Characterization of the Maleylacetate Reductase MacA of Rhodococcus opacus 1CP and Evidence for the Presence of an Isofunctional Enzyme journal July 1998
Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori: H. pylori shikimate dehydrogenase journal September 2006
β-Aminoisobutyrate-α-ketoglutarate transaminase in relation to β-aminoisobutyric aciduria journal March 1968
Overexpression of groESL in Clostridium acetobutylicum Results in Increased Solvent Production and Tolerance, Prolonged Metabolism, and Changes in the Cell's Transcriptional Program journal August 2003
Oxo Synthesis Technology journal April 1970
Nucleotide sequence of the Clostridium acidiurici ("Clostridium acidi-urici") gene for 10-formyltetrahydrofolate synthetase shows extensive amino acid homology with the trifunctional enzyme C1-tetrahydrofolate synthase from Saccharomyces cerevisiae. journal January 1988
Global Gene Expression Profiling in Escherichia coli K12: EFFECTS OF OXYGEN AVAILABILITY AND ArcA journal February 2005
Characterization of the genes of the 2,3-butanediol operons from Klebsiella terrigena and Enterobacter aerogenes. journal March 1993
Batch and continuous cultivation of Anaerobiospirillum succiniciproducens for the production of succinic acid from whey journal July 2000
Metabolic Engineering for Microbial Production and Applications of Copolyesters Consisting of 3-Hydroxybutyrate and Medium-Chain-Length 3-Hydroxyalkanoates journal February 2007
Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active-Site Saturation Test journal July 2005
Molecular cloning and functional identification of a novel phenylacetyl-CoA ligase gene from Penicillium chrysogenum journal August 2007
Production of isopropanol by metabolically engineered Escherichia coli journal November 2007
Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield journal March 2005
Identification of Novel Benzoylformate Decarboxylases by Growth Selection journal September 2006
Isolation of a versatile Serratia marcescens mutant as a host and molecular cloning of the aspartase gene. journal January 1985
Titanium-catalyzed olefin metathesis journal August 1979
Partial purification, characterization and nitrogen regulation of the lysine ?-aminotransferase of Streptomyces clavuligerus journal April 1997
Properties and Metabolic Role of Mesaconate Hydratase of an Aerobic Bacterium1 journal June 1977
The Diels-Alder Diene Synthesis. journal October 1942
Isolation and properties of a levo-lactonase from Fusarium proliferatum ECU2002: a robust biocatalyst for production of chiral lactones journal May 2007
Radical Enzymes in Anaerobes journal October 2006
Eliminating side products and increasing succinate yields in engineered strains of Escherichia coli C journal December 2008
Stereochemical and Isotopic Labeling Studies of 2-Oxo-hept-4-ene-1,7-dioate Hydratase:  Evidence for an Enzyme-Catalyzed Ketonization Step in the Hydration Reaction journal August 1998
Location of the Two Genes Encoding Glutaconate Coenzyme A-Transferase at the Beginning of the Hydroxyglutarate Operon in Acidaminococcus fermentans journal November 1994
New fadB homologous enzymes and their use in enhanced biosynthesis of medium-chain-length polyhydroxyalkanoates infadB mutantEscherichia coli journal January 2004
Industrial bioconversion of renewable resources as an alternative to conventional chemistry journal September 2004
Fermentation of 4-aminobutyrate by Clostridium aminobutyricum : cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA journal August 2000
γ-Glutamylputrescine Synthetase in the Putrescine Utilization Pathway of Escherichia coli K-12 journal May 2008
Characterization of a Three-Component Vanillate O-Demethylase from Moorella thermoacetica journal June 2001
Molecular analysis of the role of two aromatic aminotransferases and a broad-specificity aspartate aminotransferase in the aromatic amino acid metabolism of Pyrococcus furiosus journal January 2002
p-Aminobenzoate synthesis in Escherichia coli: Mutational analysis of three conserved amino acid residues of the amidotransferase PabA journal April 1993
Biological conversion of coal and coal-derived synthesis gas journal December 1993
Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity journal May 2005
Analysis of β-ketothiolase and acetoacetyl-CoA reductase genes of a methylotrophic bacterium, Paracoccus denitrifleans, and their expression in Escherichia coli journal November 1995
Determination of the metal ion dependence and substrate specificity of a hydratase involved in the degradation pathway of biphenyl/chlorobiphenyl journal February 2005
Redesign of the substrate specificity of escherichia coli aspartate aminotransferase to that of escherichia coli tyrosine aminotransferase by homology modeling and site-directed mutagenesis journal September 1995
L-lysine-.alpha.-ketoglutarate aminotransferase. II. Purification, crystallization, and properties journal November 1968
The Catalytic Intermediate Stabilized by a “Down” Active Site Loop for Diaminopimelate Decarboxylase from Helicobacter pylori: ENZYMATIC CHARACTERIZATION WITH CRYSTAL STRUCTURE ANALYSIS journal May 2008
ATP-driven electron transfer in enzymatic radical reactions journal October 2004
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri journal August 2006
Site-directed mutagenesis to enable and improve crystallizability of Candida tropicalis (3R)-hydroxyacyl-CoA dehydrogenase journal November 2004
Succinic acid production from wheat using a biorefining strategy journal July 2007
Characterization of the Genes for the Biosynthesis of the Compatible Solute Ectoine in the Moderately Halophilic Bacterium Halomonas elongata DSM 3043 journal December 1998
Identification and functional analysis of a prokaryotic‐type aspartate aminotransferase: implications for plant amino acid metabolism journal April 2006
Creation of Enantioselective Biocatalysts for Organic Chemistry by In Vitro Evolution journal January 1997
Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol journal January 2008
Wax ester fermentation in Euglena gracilis journal December 1982
Purification and characterization of an inducible L-lysine: 2-oxoglutarate 6-aminotransferase fromCandida utilis journal January 1992
The Effect of Growth Temperature on Wax Ester Content and Composition of Euglena gracilis journal June 1989
Genetic reconstruction of the aerobic central metabolism inEscherichia coli for the absolute aerobic production of succinate journal January 2004
The ald Gene, Encoding a Coenzyme A-Acylating Aldehyde Dehydrogenase, Distinguishes Clostridium beijerinckii and Two Other Solvent-Producing Clostridia fromClostridium acetobutylicum journal November 1999
Acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities journal November 2005
Crystal Structures of Unbound and Aminooxyacetate-Bound Escherichia coli γ-Aminobutyrate Aminotransferase † journal August 2004
2-Methyl-3-Hydroxybutyryl-CoA Dehydrogenase Deficiency Is Caused by Mutations in the HADH2 Gene journal May 2003
Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions journal June 2002
Malonyl-Coenzyme A Reductase in the Modified 3-Hydroxypropionate Cycle for Autotrophic Carbon Fixation in Archaeal Metallosphaera and Sulfolobus spp. journal October 2006
Cloning and heterologous expression of a broad specificity aminotransferase of Leishmania mexicana promastigotes journal December 2003
Living Ring-Opening Metathesis Polymerization in Water journal February 1998
Expression and Stereochemical and Isotope Effect Studies of Active 4-Oxalocrotonate Decarboxylase † journal February 2000
Well-Defined Ruthenium Olefin Metathesis Catalysts:  Mechanism and Activity journal April 1997
Molecular cloning, sequence analysis, and expression of the yeast alcohol acetyltransferase gene. journal January 1994
Autotracing of Escherichia coli acetate CoA-transferase α-subunit structure using 3.4 Å MAD and 1.9 Å native data journal November 2002
Chiral Compounds Synthesized by Biocatalytic Reductions [New Synthetic Methods (51)] journal June 1985
Methylthiol:coenzyme M methyltransferase from Methanosarcina barkeri, an enzyme of methanogenesis from dimethylsulfide and methylmercaptopropionate. journal January 1997
Purification and characterization of a chemotolerant alcohol dehydrogenase applicable to coupled redox reactions journal January 2004
The Metabolism of trans-Cyclohexan-1,2-diol by an Acinetobacter Species journal March 1977
Yeast Aconitase in Two Locations and Two Metabolic Pathways: Seeing Small Amounts Is Believing journal September 2005
A Novel γ-Hydroxybutyrate Dehydrogenase: IDENTIFICATION AND EXPRESSION OF AN ARABIDOPSIS cDNA AND POTENTIAL ROLE UNDER OXYGEN DEFICIENCY journal July 2003
Identification of the 4-Hydroxycinnamate Decarboxylase (PAD) Gene of Klebsiella oxytoca journal January 2008
Cloning of a DNA Fragment Carrying the 4-Hydroxycinnamate Decarboxylase ( pof K) Gene from Klebsiella oxytoca , and Its Constitutive Expression in Escherichia coli JM109 Cells journal January 1994
Cloning and expression of the two genes coding for L-serine dehydratase from Peptostreptococcus asaccharolyticus: relationship of the iron-sulfur protein to both L-serine dehydratases from Escherichia coli. journal January 1997
Expression of a Glutamate Decarboxylase Homologue Is Required for Normal Oxidative Stress Tolerance in Saccharomyces cerevisiae journal October 2000
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic study of DHNA synthetase from Geobacillus kaustophilus
  • Kanaujia, Shankar Prasad; Ranjani, Chellamuthu Vasuki; Jeyakanthan, Jeyaraman
  • Acta Crystallographica Section F Structural Biology and Crystallization Communications, Vol. 63, Issue 2 https://doi.org/10.1107/S1744309106056521
journal January 2007
Electrotransformation studies in Clostridium cellulolyticum journal November 2001
Synthesis of dl-tryptophan by modified broad specificity amino acid racemase from Pseudomonas putida IFO 12996 journal January 2007
Occurrence of Oxygen-Sensitive, NADP+-Dependent Pyruvate Dehydrogenase in Mitochondria of Euglena gracilis journal January 1984
Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases. journal January 1987
Mutants ofEscherichia coli defective in acid fermentation journal April 1988
Purification, characterisation and reaction mechanism of monofunctional 2-hydroxypentadienoic acid hydratase from Escherichia coli journal January 1998
Remarkably Broad Substrate Tolerance of Malonyl-CoA Synthetase, an Enzyme Capable of Intracellular Synthesis of Polyketide Precursors journal June 2001
Anthranilate Synthetase, an Enzyme Specified by the Tryptophan Operon of Escherichia coli: Comparative Studies on the Complex and the Subunits journal January 1969
Catalysis of the oxidation of 1,4-cyclohexadiene to benzene by electroactve binuclear rhodium complexes journal January 1990
Titanium-mediated methylene-transfer reactions. Direct conversion of esters into vinyl ethers journal April 1980
HPLC assay for methylmalonyl–CoA epimerase journal January 2003
Purification of 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans. An iron-sulfur protein journal December 1987
Stereospecific hydrogen loss in the conversion of [ 2 H 7 ]isobutyrate to β-hydroxyisobutyrate in Pseudomonas putida. The stereochemistry of β-hydroxyisobutyrate dehydrogenase journal January 1979
The role of the allosteric B site in the fumarase reaction journal February 2004
Genome-scale in silico aided metabolic analysis and flux comparisons of Escherichia coli to improve succinate production journal August 2006
De Novo Computational Design of Retro-Aldol Enzymes journal March 2008
The Biological production of ethanol from synthesis gas journal January 1989
Enhancement of lactate and succinate formation in adhE or pta-ackA mutants of NADH dehydrogenase-deficient Escherichia coli journal December 2005
The Central Metabolic Pathways of Escherichia coli: Relationship between Flux and Control at a Branch Point, Efficiency of Conversion to Biomass, and Excretion of Acetate book January 1986
Biochemical Aspects of Fumaric Acid Accumulation by Rhizopus arrhizus journal January 1986
Purification, properties, and kinetic mechanism of coenzyme A-linked aldehyde dehydrogenase from Clostridium kluyveri journal September 1980
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria. journal January 1996
Metabolic Network Analysis of an Adipoyl-7-ADCA-Producing Strain of Penicillium chrysogenum: Elucidation of Adipate Degradation journal April 2002
A novel oxalosuccinate-forming enzyme involved in the reductive carboxylation of 2-oxoglutarate in Hydrogenobacter thermophilus TK-6 journal November 2006
Minimal Reaction Sets for Escherichia coli Metabolism under Different Growth Requirements and Uptake Environments journal October 2001
Efficient Production of L-Lactic Acid by Metabolically Engineered Saccharomyces cerevisiae with a Genome-Integrated L-Lactate Dehydrogenase Gene journal April 2005
Succinyl-CoA:3-Ketoacid CoA Transferase (SCOT): Cloning of the Human SCOT Gene, Tertiary Structural Modeling of the Human SCOT Monomer, and Characterization of Three Pathogenic Mutations journal September 2000
Site-Directed Mutagenesis and Functional Analysis of the Active-Site Residues of the E2 Component of Bovine Branched-Chain .alpha.-Keto Acid Dehydrogenase Complex journal January 1994
Growth of Escherichiacoli on fatty acids: Requirement for coenzyme a transferase activity journal December 1968
Purification and Characterization of an Oxygen-Sensitive Reversible 4-Hydroxybenzoate Decarboxylase from Clostridium hydroxybenzoicum journal April 1995
MICROBIOLOGY: A Fifth Pathway of Carbon Fixation journal December 2007
Subcellular Localization of Alcohol Acetyltransferase in Strawberry Fruit. journal January 1999
Phosphotransacetylase of Escherichia coli B. activation by pyruvate and inhibition oby NADH and certain nucleotides journal December 1969
Crystal structures of the metal-dependent 2-dehydro-3-deoxy-galactarate aldolase suggest a novel reaction mechanism journal August 2000
The effect of thiamin on the activation of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in Euglena gracilis journal June 1993
A New Branch in the Family: Structure of Aspartate-β-semialdehyde Dehydrogenase from Methanococcus jannaschii journal November 2005
A novel prokaryotic trans -2-enoyl-CoA reductase from the spirochete Treponema denticola journal March 2007
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements journal March 1997
Rational construction of a 2-hydroxyacid dehydrogenase with new substrate specificity journal October 1987
Comparative Structural Analysis and Kinetic Properties of Lactate Dehydrogenases from the Four Species of Human Malarial Parasites † journal May 2004
Microbial synthesis and properties of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Comamonas acidovorans journal April 1994
Metabolic engineering of Escherichia coli for 1-butanol production journal November 2008
Trichomonas vaginalis: characterization of ornithine decarboxylase journal July 1993
Characterization of the N-acetyltransferases respectively responsible for arylalkylamine and diamine acetylation in Ascaris suum journal April 1994
Stereochemistry of the methylmalonyl-CoA decarboxylation reaction journal August 1987
Genome Sequence and Analysis of the Oral Bacterium Fusobacterium nucleatum Strain ATCC 25586 journal April 2002
Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni journal April 2007
Metabolic Engineering through Cofactor Manipulation and Its Effects on Metabolic Flux Redistribution in Escherichia coli journal April 2002
Pyruvate carboxylase from Mycobacterium smegmatis: stabilization, rapid purification, molecular and biochemical characterization and regulation of the cellular level journal July 2000
Transcriptional and Translational Regulation of α-Acetolactate Decarboxylase of Lactococcus lactissubsp. lactis journal October 2000
Expression of acetoacetyl-CoA synthetase, a novel cytosolic ketone body-utilizing enzyme, in human brain journal March 2003
The β-Ketoadipate Pathway And The Biology Of Self-Identity journal October 1996
The pimFABCDE operon from Rhodopseudomonas palustris mediates dicarboxylic acid degradation and participates in anaerobic benzoate degradation journal March 2005
NAD-Linked l(+)-Lactate Dehydrogenase from the Strict Aerobe Alcaligenes eutrophus. 2. Kinetic Properties and Inhibition by Oxaloacetate journal February 1983
Metabolic engineering of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composition in recombinantSalmonella enterica serovar typhimurium journal January 2001
Crystallographic Study of Steps along the Reaction Pathway of d -Amino Acid Aminotransferase † , ‡ journal April 1998
An extremely thermostable aldolase from Sulfolobus solfataricus with specificity for non-phosphorylated substrates journal October 1999
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants the Keio collection journal February 2006
New vectors for co-expression of proteins: Structure of Bacillus subtilis ScoAB obtained by high-throughput protocols journal June 2007
Construction of an Escherichia coli K-12 Mutant for Homoethanologenic Fermentation of Glucose or Xylose without Foreign Genes journal January 2007
Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus journal August 2008
The microsomal dicarboxylyl-CoA synthetase journal September 1985
Purification, crystallization and preliminary X-ray crystallographic studies on acetolactate decarboxylase journal May 2003
Metabolic engineering of Escherichia coli for the production of putrescine, a four carbon diamine journal January 2009
Comparison of Three Enoate Reductases and their Potential Use for Biotransformations journal June 2007
Structure of the Escherichia coli Fumarate Reductase Respiratory Complex journal June 1999
Acetogenesis, Acetogenic Bacteria, and the Acetyl-CoA “Wood/Ljungdahl” Pathway: Past and Current Perspectives book January 1994
Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water journal September 1983
Energy Conservation in Acetogenic Bacteria journal November 2003
Active Site Analysis of the Potential Antimicrobial Target Aspartate Semialdehyde Dehydrogenase journal December 2001
Crystallization and preliminary X-ray analysis of recombinant glutamate mutase and of the isolated component S from Clostridium cochlearium journal September 1998
The Escherichia coli gabDTPC Operon: Specific γ-Aminobutyrate Catabolism and Nonspecific Induction journal December 2002
Dehydroquinate synthetase from Escherichia coli: purification, cloning, and construction of overproducers of the enzyme journal September 1984
Tracer studies of the interconversion of R- and S-methylmalonic semialdehydes in man journal October 1985
Characterization of a Bifunctional Archaeal Acyl Coenzyme A Carboxylase journal February 2003
MetaCyc: a multiorganism database of metabolic pathways and enzymes journal January 2006
Characterization of yeast homoserine dehydrogenase, an antifungal target: the invariant histidine 309 is important for enzyme integrity journal January 2001
Formate hydrogenlyase in the hyperthermophilic archaeon, Thermococcus litoralis journal January 2008
Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis journal September 1999
Molecular characterization of the phenylacetic acid catabolic pathway in Pseudomonas putida U: The phenylacetyl-CoA catabolon journal May 1998
Purification and characterisation of acetolactate decarboxylase from Leuconostoc lactis NCW1 journal January 2001
Environmentally compatible synthesis of adipic acid from D-glucose journal January 1994
Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate journal February 1998
Construction of a set ofSaccharomyces cerevisiae vectors designed for recombinational cloning journal January 2003
2-Hydroxyisocaproyl-CoA dehydratase and its activator from Clostridium difficile: 2-Hydroxyisocaproyl-CoA dehydratase journal December 2004
Metabolic Analysis of Escherichia coli in the Presence and Absence of the Carboxylating Enzymes Phosphoenolpyruvate Carboxylase and Pyruvate Carboxylase journal May 2000
Analysis of Storage Lipid Accumulation in Alcanivorax borkumensis: Evidence for Alternative Triacylglycerol Biosynthesis Routes in Bacteria journal November 2006
Long-Chain Aldehyde Dehydrogenase That Participates in n-Alkane Utilization and Wax Ester Synthesis in Acinetobacter sp. Strain M-1 journal August 2000
Effects of edd and pgi Disruptions on Inosine Accumulation in Escherichia coli journal January 2005
Cloning, sequencing and overexpression of the leucine dehydrogenase gene from Bacillus cereus1 journal April 1997
The Fumarase Genes of Escherichia coli: Location of the fumB Gene and Discovery of a New Gene (fumC) journal November 1985
The dihydroxyacetone kinase of Escherichia coli utilizes a phosphoprotein instead of ATP as phosphoryl donor journal May 2001
Pyruvate Ferredoxin Oxidoreductase and Its Radical Intermediate † journal June 2003
Fumaric acid production from hydrolysates of starch-based substrates journal January 1992
Nucleotide sequence of the Bacillus licheniformis ATCC 10716 dat gene and comparison of the predicted amino acid sequence with those of other bacterial species journal January 1997
Microbiology of synthesis gas fermentation for biofuel production journal June 2007
The role of enoyl-CoA hydratase in the metabolism of isoleucine byPseudomonas putida journal April 1978
Highly Stable l-Lysine 6-Dehydrogenase from the Thermophile Geobacillus stearothermophilus Isolated from a Japanese Hot Spring: Characterization, Gene Cloning and Sequencing, and Expression journal February 2004
The physiological role of oxygen-sensitive pyruvate dehydrogenase in mitochondrial fatty acid synthesis in Euglena gracilis journal March 1985
Living Ring-Opening Metathesis Polymerization in Aqueous Media Catalyzed by Well-Defined Ruthenium Carbene Complexes journal January 1996
Reduction of Carboxylic Acids by Nocardia Aldehyde Oxidoreductase Requires a Phosphopantetheinylated Enzyme journal November 2006
Poly[(R)-3-hydroxybutyrate] formation in Escherichia coli from glucose through an enoyl-CoA hydratase-mediated pathway journal January 2007
Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme journal October 2008
Malonyl-Coenzyme A Reductase from Chloroflexus aurantiacus, a Key Enzyme of the 3-Hydroxypropionate Cycle for Autotrophic CO2 Fixation journal May 2002
Cyclohexane Carboxylate and Benzoate Formation from Crotonate in Syntrophus aciditrophicus journal December 2006
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: Identification of α-ketoglutarate decarboxylase journal July 2005
Expression ofSulfolobus solfataricus trpEandtrpGGenes inE.coli journal January 1997
3-Hydroxypropionyl-Coenzyme A Dehydratase and Acryloyl-Coenzyme A Reductase, Enzymes of the Autotrophic 3-Hydroxypropionate/4-Hydroxybutyrate Cycle in the Sulfolobales journal May 2009
Effect of ArcA and FNR on the expression of genes related to the oxygen regulation and the glycolysis pathway inEscherichia coli under microaerobic growth conditions journal January 2005
Metabolic Engineering of a Novel Propionate-Independent Pathway for the Production of Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) in Recombinant Salmonella enterica Serovar Typhimurium journal August 2002
The phosphoenolpyruvate carboxylase gene of Corynebacterium glutamicum: Molecular cloning, nucleotide sequence, and expression journal August 1989
α-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus journal July 2004
Chemical, Physical and Enzymatic Comparisons of Formyltetrahydrofolate Synthetases from Thermo- and Mesophilic Clostridia book January 1976
Degenerate oligonucleotide gene shuffling (DOGS) and random drift mutagenesis (RNDM): Two complementary techniques for enzyme evolution journal June 2005
Anaerobic degradation of aniline and dihydroxybenzenes by newly isolated sulfate-reducing bacteria and description of Desulfobacterium anilini journal November 1989
Characterization of a (2 R ,3 R )-2,3-Butanediol Dehydrogenase as the Saccharomyces cerevisiae YAL060W Gene Product : DISRUPTION AND INDUCTION OF THE GENE journal August 2000
Active acetyl-CoA synthase from Clostridium thermoaceticum obtained by cloning and heterologous expression of acsAB in Escherichia coli journal October 2000
Molecular Cloning of the nemA Gene Encoding N-Ethylmaleimide Reductase from Escherichia coli. journal January 1997
p-Aminobenzoic acid and chloramphenicol biosynthesis in Streptomyces venezuelae: gene sets for a key enzyme, 4-amino-4-deoxychorismate synthase The GenBank accession number for the sequence reported in this paper is AF189258. journal August 2001
Enzyme kinetics in reversed micelles. 2. Behaviour of enoate reductase journal January 1990
Solubilization and partial characterization of particulate dehydrogenases from Clostridium kluyveri journal January 1974
Functional Expression of Horseradish Peroxidase in E. coli by Directed Evolution journal June 1999
PET genes of Saccharomyces cerevisiae. journal January 1990
Crystallization of butyrate kinase 2 from Thermotoga maritima mediated by vapor diffusion of acetic acid journal May 2003
Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli journal September 1988
Succinyl-CoA:(R)-Benzylsuccinate CoA-Transferase: an Enzyme of the Anaerobic Toluene Catabolic Pathway in Denitrifying Bacteria journal July 2001
Genetic and biochemical characterization of a short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosu s: Short-chain ADH of Pyrococcus journal May 2001
Transcriptional regulation of ketone body-utilizing enzyme, acetoacetyl-CoA synthetase, by C/EBPα during adipocyte differentiation journal June 2008
Characterization of an acetyl-CoA C-acetyltransferase (thiolase) gene from Clostridium acetobutylicum ATCC 824 journal February 1995
Specificity Determinants for the Pyruvate Dehydrogenase Component Reaction Mapped with Mutated and Prosthetic Group Modified Lipoyl Domains journal April 2000
Efficient Succinic Acid Production from Glucose through Overexpression of Pyruvate Carboxylase in an Escherichia coli Alcohol Dehydrogenase and Lactate Dehydrogenase Mutant journal January 2005
Cloning and expression of the Escherichia coli K-12 sad gene. journal January 1988
Cloning structural gene sacB, which codes for exoenzyme levansucrase of Bacillus subtilis: expression of the gene in Escherichia coli. journal January 1983
The effects of alternate optimal solutions in constraint-based genome-scale metabolic models journal October 2003
Nematode.net update 2008: improvements enabling more efficient data mining and comparative nematode genomics journal January 2009
Pyruvate Formate-lyase and a Novel Route of Eukaryotic ATP Synthesis in Chlamydomonas Mitochondria journal February 2006
Simplified generation of targeting constructs using ET recombination journal September 1999
Cloning of multiple genes involved with cobalamin (Vitamin B12) biosynthesis in Bacillus megaterium. journal January 1986
Functional Characterization by Genetic Complementation of aroB-Encoded Dehydroquinate Synthase from Mycobacterium tuberculosis H37Rv and Its Heterologous Expression and Purification journal June 2007
Gene Cloning and Molecular Characterization of Lysine Decarboxylase from Selenomonas ruminantiumDelineate Its Evolutionary Relationship to Ornithine Decarboxylases from Eukaryotes journal December 2000
Connection between Poly-β-Hydroxybutyrate Biosynthesis and Growth on C1 and C2 Compounds in the Methylotroph Methylobacterium extorquensAM1 journal February 2001
Cloning and genetic organization of the pca gene cluster from Acinetobacter calcoaceticus. journal January 1987
Use of the Rhodopseudomonas palustris genome sequence to identify a single amino acid that contributes to the activity of a coenzyme A ligase with chlorinated substrates: 3-Chlorobenzoate degradation journal December 2004
Purification, Crystallization, and Molecular Properties of Aspartase from Pseudomonas fluorescens1 journal January 1984
Crystal Structure of Shikimate Kinase from Mycobacterium tuberculosis Reveals the Dynamic Role of the LID Domain in Catalysis journal June 2002
High cell density media for Escherichia coli are generally designed for aerobic cultivations – consequences for large-scale bioprocesses and shake flask cultures journal January 2008
Initial Kinetic and Mechanistic Characterization of Escherichia coli Fumarase A journal June 1994
Directed evolution of an aspartate aminotransferase with new substrate specificities journal May 1998
Crystal Structure of Butyrate Kinase 2 from Thermotoga maritima, a Member of the ASKHA Superfamily of Phosphotransferases journal February 2009
Two Membrane-Associated NiFeS-Carbon Monoxide Dehydrogenases from the Anaerobic Carbon-Monoxide-Utilizing Eubacterium Carboxydothermus hydrogenoformans journal September 2001
Comparative genomics provides evidence for the 3-hydroxypropionate autotrophic pathway in filamentous anoxygenic phototrophic bacteria and in hot spring microbial mats journal August 2007
Evidence for isofunctional enzymes in the degradation of phenol, m- and p-toluate, and p-cresol via catechol meta-cleavage pathways in Alcaligenes eutrophus. journal January 1984
Structural Basis for Shikimate-Binding Specificity of Helicobacter pylori Shikimate Kinase journal December 2005
Enhanced degradation of polychlorinated biphenyls by directed evolution of biphenyl dioxygenase journal July 1998
Propionate, a source of β-alanine, is an inhibitor of β-alanine methylation in Limonium latifolium, Plumbaginaceae journal January 2002
Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli journal May 2005
DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. journal October 1994
Crystal structure of muconolactone isomerase at 3.3 Å resolution journal February 1989
OptStrain: A computational framework for redesign of microbial production systems journal November 2004
Biobutanol: An attractive biofuel journal December 2007
Mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency: An inborn error of isoleucine and ketone body metabolism journal January 1993
Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes ?-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) fromSchizosaccharomyces pombe journal January 2004
Production of d(-)-lactate from sucrose and molasses journal May 2004
Reconstruction and Validation of Saccharomyces cerevisiae iND750, a Fully Compartmentalized Genome-Scale Metabolic Model journal June 2004
Microbial Cellulose Utilization: Fundamentals and Biotechnology journal September 2002
Simple constrained-optimization view of acetate overflow inE. coli journal March 1990
Microbial Production of Acetone/Butanol/Isopropanol book May 2001
Nucleotide sequence and expression of the Enterobacter aerogenes alpha-acetolactate decarboxylase gene in brewer's yeast. journal January 1988
Enzymes of a novel autotrophic CO2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle journal August 1993
Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations. journal July 1994
[45] Chemostats used for studying natural selection and adaptive evolution book January 1993
3-Hydroxyisobutyryl-CoA Hydrolase book January 2000
Isoamyl alcohol-induced morphological change in involves increases in mitochondria and cell wall chitin content journal October 2004
Bioremediation of ε-Caprolactam from Nylon-6 Waste Water by Use of Pseudomonas aeruginosa MCM B-407 journal September 1998
Iterative Saturation Mutagenesis on the Basis of B Factors as a Strategy for Increasing Protein Thermostability journal November 2006
Fatty acid synthesis in mitochondria of Euglena gracilis journal July 1984
Sequence organization and regulation of the Bacillus subtilis menBE operon. journal January 1992
Constitutive expression of catABC genes in the aniline-assimilating bacterium Rhodococcus species AN-22: production, purification, characterization and gene analysis of CatA, CatB and CatC journal December 2005
Selective synthesis of isobutanol by means of the Guerbet reaction journal June 2003
Nucleotide sequence of the promoter and fadB gene of the fadBA operon and primary structure of the multifunctional fatty acid oxidation protein from Escherichia coli journal July 1991
In silico design and adaptive evolution of Escherichia coli for production of lactic acid journal September 2005
Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate journal September 2007
A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework journal December 1988
Enhanced hydrogen production from glucose by metabolically engineered Escherichia coli journal October 2007
Microbial production of R-3-hydroxybutyric acid by recombinant E. coli harboring genes of phbA, phbB, and tesB journal July 2007
Biotin-requiring mutants of Escherichia coli K-12. journal January 1967
Purification and Some Properties of a Hitherto-Unknown Enzyme Reducing the Carbon-Carbon Double Bond of alpha,beta-Unsaturated Carboxylate Anions journal June 1979
The pentafunctional arom enzyme of Saccharomyces cerevisiae is a mosaic of monofunctional domains journal September 1987
Expression of Clostridium acetobutylicumATCC 824 Genes in Escherichia coli for Acetone Production and Acetate Detoxification journal March 1998
Metabolic engineering of Escherichia coli for the production of malic acid journal June 2008
Toward Metabolic Phenomics: Analysis of Genomic Data Using Flux Balances journal June 1999
Improved expression of human interleukin-2 in high-cell-density fermentor cultures of Escherichia coli K-12 by a phosphotransacetylase mutant. journal January 1990
Large-scale mutational analysis for the annotation of the mouse genome journal February 2002
Long-term continuous evolution of acetate resistantAcetobacter aceti journal August 2003
Fat synthesis in adipose tissue. An examination of stoichiometric constraints journal September 1986
Oxidoreductase-Type Enzymes and Redox Proteins Involved in Fermentative Metabolisms of Hyperthermophilic Archaea book January 1996
Novel Substrate Specificity of Designer 3-Isopropylmalate Dehydrogenase Derived from Thermus thermophilus HB8 journal January 2001
Kinetic characterization of the carbon monoxide-acetyl-CoA (carbonyl group) exchange activity of the acetyl-CoA synthesizing carbon monoxide dehydrogenase from Clostridium thermoaceticum journal October 1988
Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex journal December 2006
Metabolic Pathway for Biosynthesis of Poly (3-Hydroxybutyrate-co-4-Hydroxybutyrate) from 4-Hydroxybutyrate by Alcaligenes eutrophus journal January 1995
Molecular evolution by staggered extension process (StEP) in vitro recombination journal March 1998
Byproduct identification in the terephthalic acid production process and possible mechanisms of their formation journal December 1984
Properties of Nicotinamide Adenine Dinucleotide Phosphate-Dependent Formate Dehydrogenase from Clostridium thermoaceticum journal January 1966
Propionyl-CoA condensing enzyme from Ascaris muscle mitochondria journal February 1991
A combinatorial approach to hybrid enzymes independent of DNA homology journal December 1999
Polypeptide Release Factors in Prokaryotes and Eukaryotes journal January 2002
The Serratia marcescens bioH gene encodes an esterase journal January 2003
Simultaneous Production and Recovery of Fumaric Acid from Immobilized Rhizopus oryzae with a Rotary Biofilm Contactor and an Adsorption Column. journal January 1996
The role and control of the glyoxylate cycle in Escherichia coli journal April 1966
Functional expression of prokaryotic and eukaryotic genes in Escherichia coli for conversion of glucose to pp-hydroxystyrene journal May 2007
The Complete Stereochemistry of the Enzymatic Dehydration of 4-Hydroxybutyryl Coenzyme A to Crotonyl Coenzyme A journal April 2008
Genetic, physiological and biochemical characterization of multiple methanol methyltransferase isozymes in Methanosarcina acetivorans C2A: Methyltransferase isozymes in Methanosarcina species journal March 2005
Pyruvate:NADP+ oxidoreductase from Euglena gracilis: Mechanism of O2-inactivation of the enzyme and its stability in the aerobe journal August 1990
New insights and novel developments in clostridial acetone/butanol/isopropanol fermentation journal June 1998
A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria journal January 2006
Isolation, nucleotide sequence analysis, and disruption of the MDH2 gene from Saccharomyces cerevisiae: evidence for three isozymes of yeast malate dehydrogenase. journal January 1991
Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface journal June 1999
Electro-enzymic viologen-mediated stereospecific reduction of 2-enoates with free and immobilized enoate reductase on cellulose filters or modified carbon electrodes journal July 1987
Cloning, characterization, and sequence analysis of the clcE gene encoding the maleylacetate reductase of Pseudomonas sp. strain B13. journal January 1997
Isolation and partial characterization of a broad specificity aminotransferase from Leishmania mexicana promastigotes journal October 1998
Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences journal July 1988
Novel enzyme reactions related to the tricarboxylic acid cycle: phylogenetic/functional implications and biotechnological applications journal February 2007
Die Alanatreduktion von β-Carbonyl-oxalylsäure-estern journal October 1959
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon. journal January 1996
Enzymic synthesis of ϵ-N-acetyl-l-lysine journal November 1964
Role of branched-chain 2-oxo acid dehydrogenase and pyruvate dehydrogenase in 2-oxobutyrate metabolism journal March 1986
Crystallization of diaminopimelate decarboxylase from Escherichia coli , a stereospecific D -amino-acid decarboxylase journal February 2002
Plasmid-mediated uptake and metabolism of sucrose by Escherichia coli K-12. journal January 1982
Mechanisms of Protein Import into Mitochondria journal April 2003
Prediction of protein function from protein sequence and structure journal January 1999
Structure and regulation of acetyl-CoA carboxylase genes of metazoa journal March 2005
The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity journal April 2002
The MtsA Subunit of the Methylthiol:Coenzyme M Methyltransferase of Methanosarcina barkeri Catalyses Both Half-reactions of Corrinoid-dependent Dimethylsulfide: Coenzyme M Methyl Transfer journal November 2000
Thermotoga maritima 3-Deoxy-D- arabino -heptulosonate 7-Phosphate (DAHP) Synthase: THE ANCESTRAL EUBACTERIAL DAHP SYNTHASE? journal May 2003
Anaerobic regulation of the adhE gene, encoding the fermentative alcohol dehydrogenase of Escherichia coli. journal January 1993
Production of Fumaric Acid by Rhizopus arrhizus1 journal January 1959
Malic Acid Production by Saccharomyces cerevisiae: Engineering of Pyruvate Carboxylation, Oxaloacetate Reduction, and Malate Export journal March 2008
Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe-4S] cluster and flavin journal October 2004
Diels-Alder reactions II: The Reaction Mechanism journal January 1967
Cloning, Sequencing, and Expressions of Genes Encoding Enzymes of the Autotrophic Acetyl-CoA Pathway in the Acetogen Clostridium thermoaceticum book January 1993
A New Type of Glucose Fermentation by Clostridium thermoaceticum journal January 1942
Mechanistic Analysis of the argE -Encoded N -Acetylornithine Deacetylase † journal February 2000
Genetic analysis of the proBA genes of Salmonella typhimurium: physical and genetic analyses of the cloned proB+ A+ genes of Escherichia coli and of a mutant allele that confers proline overproduction and enhanced osmotolerance. journal January 1983
Metabolic Pathways for Cytotoxic End Product Formation from Glutamate- and Aspartate-Containing Peptides byPorphyromonas gingivalis journal September 2000
Purification and characterization of cis-aconitic acid decarboxylase from Aspergillus terreus TN484-M1 journal July 2002
Purification, characterization, DNA sequence and cloning of a pimeloyl-CoA synthetase from Pseudomonas mendocina 35 journal June 1999
Physical and Genetic Interactions of Cytosolic Malate Dehydrogenase with Other Gluconeogenic Enzymes journal May 2003
Stereoselectivity and stereospecificity of the α,β-dihydroxyacid dehydratase and from Salmonella typhimurium journal July 1977
Purification and Characterization of 6-Aminohexanoic-Acid-Oligomer Hydrolase of Flavobacterium sp. KI72 journal June 1981
Regulation by lipids of cofactor binding to a peripheral membrane enzyme: binding of thiamin pyrophosphate to pyruvate oxidase journal July 1977
Expression ofAscaris suum malic enzyme in a mutantEscherichia coli allows production of succinic acid from glucose journal March 1997
Metabolic gene–deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes journal September 2004
Actin polymerization induced by calspectin, a calmodulin-binding spectrinlike protein journal November 1982
Cloning, sequencing, and expression of the gene encoding methylmalonyl-coenzyme A mutase from Streptomyces cinnamonensis. journal January 1993
Characterization of strain HY99, a novel microorganism capable of aerobic and anaerobic degradation of aniline journal September 2000
On the mammalian acetone metabolism: from chemistry to clinical implications journal May 2003
Cloning and characterization of the bifunctional alcohol/acetaldehyde dehydrogenase gene (adhE) in Leuconostoc mesenteroides isolated from kimchi journal April 2005
p-Aminobenzoate synthesis in Escherichia coli: kinetic and mechanistic characterization of the amidotransferase PabA journal August 1992
Evaluation of 5-enolpyruvoylshikimate-3-phosphate synthase substrate and inhibitor binding by stopped-flow and equilibrium fluorescence measurements journal March 1988
A novel enzyme, citryl-CoA synthetase, catalysing the first step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6 journal March 2004
A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation journal January 2004
Effects of Deletions at the Carboxyl Terminus of Zymomonas mobilis Pyruvate Decarboxylase on the Kinetic Properties and Substrate Specificity † journal August 2000
Propionyl-Coenzyme A Synthase from Chloroflexus aurantiacus, a Key Enzyme of the 3-Hydroxypropionate Cycle for Autotrophic CO2 Fixation journal January 2002
Physicochemical, Catalytic, and Immunochemical Properties of Fumarases Crystallized Separately from Mitochondrial and Cytosolic Fractions of Rat Liver1 journal April 1981
Residue Leu-641 of Acetyl-CoA Synthetase is Critical for the Acetylation of Residue Lys-609 by the Protein Acetyltransferase Enzyme of Salmonella enterica journal May 2005
Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida journal June 2005
Identification of a Sex-factor-affinity Site in E. coli as    journal January 1981
Bioprocessing of coal-derived synthesis gases by anaerobic bacteria journal January 1992
Crystal Structure of Mycobacterium tuberculosis Diaminopimelate Decarboxylase, an Essential Enzyme in Bacterial Lysine Biosynthesis journal March 2003
Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress journal November 2005
Anaerobic degradation of cyclohexane-1,2-diol by a new Azoarcus species journal September 1997
Transversion-enriched sequence saturation mutagenesis (SeSaM-Tv+): A random mutagenesis method with consecutive nucleotide exchanges that complements the bias of error-prone PCR journal January 2008
Reactor Design Issues for Synthesis-Gas Fermentations journal October 1999
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors journal January 1985
Tungsten, a component of active formate dehydrogenase from Clostridium thermoaceticum journal June 1975
Purification and characterisation of a novel iso-propanol dehydrogenase from Phytomonas sp. journal April 1997
The Methanosarcina barkeri Genome: Comparative Analysis with Methanosarcina acetivorans and Methanosarcina mazei Reveals Extensive Rearrangement within Methanosarcinal Genomes journal September 2006
Nicotinic Acid Metabolism. Dimethylmaleate Hydratase journal January 1984
Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study
  • Maes, Dominique; Crabeel, Marjolaine; Van de Weerdt, Cécile
  • Acta Crystallographica Section F Structural Biology and Crystallization Communications, Vol. 62, Issue 12 https://doi.org/10.1107/S1744309106050561
journal November 2006
Crystal Structure of Novel NADP-dependent 3-Hydroxyisobutyrate Dehydrogenase from Thermus thermophilus HB8 journal September 2005
Restricted Distribution of the Butyrate Kinase Pathway among Butyrate-Producing Bacteria from the Human Colon journal April 2004
Expression in Escherichia coli of Native and Chimeric Phenolic Acid Decarboxylases with Modified Enzymatic Activities and Method for Screening Recombinant E. coli Strains Expressing These Enzymes journal March 2001
Specificity of Aspartokinase III fromEscherichia coliand an Examination of Important Catalytic Residues journal November 1996
Purification, characterization and mode of action of PdhR, the transcriptional repressor of the pdhR?aceEF?Ipd operon of Escherichia coli journal February 1995
The Mechanism of Substrate Activation of Pyruvate Decarboxylase: A First Approach journal December 1978
Methylmalonyl-CoA Decarboxylase from Propionigenium Modestum. Cloning and Sequencing of the Structural Genes and Purification of the Enzyme Complex journal December 1997
Identification of the active-site lysine residues of two biosynthetic 3-dehydroquinases journal April 1991
Biotechnology of succinic acid production and markets for derived industrial products journal May 1999
Electrotransformation of Clostridium acetobutylicum ATCC 824 using high-voltage radio frequency modulated square pulses journal February 2000
The Identification of a Succinyl-CoA Thioesterase Suggests a Novel Pathway for Succinate Production in Peroxisomes journal August 2005
Catalytic reaction of 1,3-butanediol over solid acids journal August 2006
Post-translational activation introduces a free radical into pyruvate formate-lyase. journal March 1984
Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous journal October 1990
A general model of error-prone PCR journal June 2005
Theory for the Systemic Definition of Metabolic Pathways and their use in Interpreting Metabolic Function from a Pathway-Oriented Perspective journal April 2000
Rapid modification of bacterial artificial chromosomes by ET- recombination journal March 1999
On the Kinetics and Mechanism of Enoate Reductase journal January 1982
Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from Clostridium sticklandii journal January 1974
Cloning and Sequencing of the Coenzyme B 12 -binding Domain of Isobutyryl-CoA Mutase from Streptomyces cinnamonensis , Reconstitution of Mutase Activity, and Characterization of the Recombinant Enzyme Produced in Escherichia coli journal October 1999
Rapid and Efficient Electrocatalytic CO 2 /CO Interconversions by Carboxydothermus hydrogenoformans CO Dehydrogenase I on an Electrode journal August 2007
Cloning, sequencing, expression, purification and preliminary characterization of a type II dehydroquinase from Helicobacter pylori journal October 1996
Production and composition of wax esters by fermentation of Euglena gracilis. journal January 1983
Genome shuffling of Lactobacillus for improved acid tolerance journal July 2002
An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR) journal August 2003
The isolation and nucleotide sequence of the complex AROM locus of Aspergillus nidulans journal January 1986
A comparison of the enzymological and biophysical properties of two distinct classes of dehydroquinase enzymes journal March 1992
A Novel Bifunctional Wax Ester Synthase/Acyl-CoA:Diacylglycerol Acyltransferase Mediates Wax Ester and Triacylglycerol Biosynthesis in Acinetobacter calcoaceticus ADP1 journal December 2002
Validation of a Metabolic Network for Saccharomyces cerevisiae Using Mixed Substrate Studies journal August 1996
Crystal Structure of Methylmalonyl-Coenzyme A Epimerase from P. shermanii journal July 2001
Cysteine sulfinate aminotransferase and aspartate aminotransferase isoenzymes of rat brain. Purification, characterization, and further evidence for identity journal September 1980
Two succinic semialdehyde dehydrogenases are induced when Escherichia coli K-12 Is grown on gamma-aminobutyrate. journal January 1981
Bimetallic nanocatalysts for the conversion of muconic acid to adipic acidElectronic supplementary information (ESI) available: experimental details, EXAFS fit and refined EXAFS parameters. See http://www.rsc.org/suppdata/cc/b3/b300203a/ journal April 2003
Electro-transformation of Clostridium beijerinckii NRRL B-592 with shuttle plasmid pHR106 and recombinant derivatives journal March 1994
A 3-Hydroxypropionate/4-Hydroxybutyrate Autotrophic Carbon Dioxide Assimilation Pathway in Archaea journal December 2007
Structural Basis for a Change in Substrate Specificity:  Crystal Structure of S113E Isocitrate Dehydrogenase in a Complex with Isopropylmalate, Mg 2+ , and NADP † , ‡ journal April 2001
The Structure of 3-Methylaspartase from Clostridium tetanomorphum Functions via the Common Enolase Chemical Step journal December 2001
Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing β-proteobacterium journal January 2003
The Yeast ARG7 Gene Product Is Autoproteolyzed to Two Subunit Peptides, Yielding Active Ornithine Acetyltransferase journal April 2000
A re-examination of the pathway for ornithine biosynthesis in a thermophilic and two mesophilic Bacillus species journal January 1992
Transcriptional regulation of the aconitase genes (acnA and acnB) of Escherichia coli journal December 1997
Studies on the subunits of Escherichia coli coenzyme a transferase journal October 1979
Acetyl:Succinate CoA-transferase in Procyclic Trypanosoma brucei: GENE IDENTIFICATION AND ROLE IN CARBOHYDRATE METABOLISM journal August 2004
Acetyl-coenzyme A synthesis from methyltetrahydrofolate, CO, and coenzyme A by enzymes purified from Clostridium thermoaceticum: attainment of in vivo rates and identification of rate-limiting steps. journal January 1992
Biochemical production capabilities ofescherichia coli journal June 1993
Characterization of a Gene Cluster Involved in 4-Chlorocatechol Degradation by Pseudomonas reinekei MT1 journal May 2009
The Reactivity of Gamma-hydroxybutyric acid (GHB) and Gamma-butyrolactone (GBL) in Alcoholic Solutions journal January 2004
Crystal Structure of a Glycyl Radical Enzyme from Archaeoglobus fulgidus journal March 2006
The Enigmatic Escherichia coli fadE Gene Is yafH journal July 2002
Primary structure of the thermostable formyltetrahydrofolate synthetase from Clostridium thermoaceticum journal June 1990
Production of isoamyl acetate in ackA-pta and/or ldh mutants of Escherichia coli with overexpression of yeast ATF2 journal February 2004
Biosynthesis of enantiopure (S)-3-hydroxybutyric acid in metabolically engineered Escherichia coli journal June 2008
Sequence of the Escherichia coli C homoprotocatechuic acid degradative operon completed with that of the 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase-encoding gene (hpcH) journal December 1995
Purification and characteristics of a gamma-glutamyl kinase involved in Escherichia coli proline biosynthesis. journal January 1984
Partial purification and characterization of glutaryl-coenzyme A dehydrogenase, electron transfer flavoprotein, and electron transfer flavoprotein-Q oxidoreductase from Paracoccus denitrificans. journal January 1985
L-threonine dehydrogenase of Escherichia coli K-12 journal November 1978
The delta (argF-lacZ)205(U169) deletion greatly enhances resistance to hydrogen peroxide in stationary-phase Escherichia coli. journal January 1994
NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat journal September 1989
Engineering of Ralstonia eutropha for Production of Poly(3-hydroxybutyrate- co -3-hydroxyhexanoate) from Fructose and Solid-State Properties of the Copolymer journal May 2002
Rapid evolution of a protein in vitro by DNA shuffling journal August 1994
Radical species in the catalytic pathways of enzymes from anaerobes journal December 1998
A novel member of the GCN5-related N-acetyltransferase superfamily from Caenorhabditis elegans preferentially catalyses the N-acetylation of thialysine [S-(2-aminoethyl)-L-cysteine] journal November 2004
Cleavage-dependent Ligation by the FLP Recombinase: CHARACTERIZATION OF A MUTANT FLP PROTEIN WITH AN ALTERATION IN A CATALYTIC AMINO ACID journal September 1995
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels journal January 2008
Metabolic Flux Balancing: Basic Concepts, Scientific and Practical Use journal October 1994
3-Hydroxyisobutyrate Dehydrogenase from Pseudomonas putida E23: Purification and Characterization journal January 1996
Economical succinic acid production from cane molasses by Actinobacillus succinogenes journal April 2008
Structure of [NiFe] Hydrogenase Maturation Protein HypE from Escherichia coli and Its Interaction with HypF journal December 2007
The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution:  Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes † , ‡ journal July 1998
The level of pyruvate-formate lyase controls the shift from homolactic to mixed-acid product formation in Lactococcus lactis journal March 2002
Stereospecificity and stereochemical infidelity of acetoacetate decarboxylase (AAD) journal February 1981
Purification and properties of the α-acetolactate decarboxylase from Lactococcus lactis subsp. lactis NCDO 2118 journal August 1994
Interactions of the Antizyme AtoC with Regulatory Elements of the Escherichia coli atoDAEB Operon journal July 2007
Enzymatic Hydrogenation of trans -2-Nonenal in Barley journal November 2005
Catabolism of α-Ketoglutarate by a sucA Mutant of Bradyrhizobium japonicum: Evidence for an Alternative Tricarboxylic Acid Cycle journal May 2000
Isolation of a Degeneration-Resistant Mutant of Clostridium acetobutylicum NCIMB 8052 journal January 1993
Crystal Structure of Beta-Lactam Synthetase report June 2001
Studies on the metabolism of unsaturated fatty acids. V. Isomerization of thiol esters of cis-2-alkenoic acids during their preparation and alkaline hydrolysis. journal January 1982
In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production journal November 2005
The biotin-dependent sodium ion pump glutaconyl-CoA decarboxylase from Fusobacterium nucleatum (subsp. nucleatum): Comparison with the glutaconyl-CoA decarboxylases from gram-positive bacteria journal September 1990
Development of a metabolic network design and optimization framework incorporating implementation constraints: A succinate production case study journal January 2006
Purification and characterization of two enone reductases from Saccharomyces cerevisiae journal July 1998
Selective catalytic dehydrogenation of 1,4-cyclohexadiene to benzene. 1. Radical anions derived from transition-metal arene complexes as promoters journal October 1988
2-Aminoadipate-2-Oxoglutarate Aminotransferase Isoenzymes in Human Liver: A Plausible Physiological Role in Lysine and Tryptophan Metabolism journal January 1993
Conversion of a β-Ketoacyl Synthase to a Malonyl Decarboxylase by Replacement of the Active-Site Cysteine with Glutamine journal September 1999
A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase journal October 2004
Succinate-ethanol fermentation in Clostridium kluyveri: purification and characterisation of 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA ?3-?2-isomerase journal March 1994
In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data journal February 2001
Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis journal July 1998
Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes journal April 2007
Developments in Directed Evolution for Improving Enzyme Functions journal August 2007
First direct observation of the simultaneous presence and of the interconversion of chain-propagating metal-carbene and metallacyclobutane complexes in a catalytic olefin metathesis reaction: the ring-opening polymerization of norbornene journal February 1987
Clostridium carboxidivorans sp. nov., a solvent-producing clostridium isolated from an agricultural settling lagoon, and reclassification of the acetogen Clostridium scatologenes strain SL1 as Clostridium drakei sp. nov. journal September 2005
Mycelial Pellet Formation by Rhizopus oryzae ATCC 20344 book January 2000
Enzymology and Evolution of the Pyruvate Pathway to 2-Oxobutyrate in Methanocaldococcus jannaschii journal April 2007
Characterisation of the diol dehydratase pdu operon of Lactobacillus collinoides journal March 2002
Reversible interconversion of carbon dioxide and formate by an electroactive enzyme journal July 2008
Methanol : coenzyme M methyltransferase from Methanosarcina barkeri . Identification of the active-site histidine in the corrinoid-harboring subunit MtaC by site-directed mutagenesis journal May 1998
Kinetic and Chemical Mechanism of Mycobacterium tuberculosis 1-Deoxy- d -xylulose-5-phosphate Isomeroreductase † journal April 2004
SCALEs: multiscale analysis of library enrichment journal November 2006
Genes coding for the benzoyl-CoA pathway of anaerobic aromatic metabolism in the bacterium Thauera aromatica journal August 1998
[27] Random chimeragenesis by heteroduplex recombination book January 2000
Screening of two complementary collections of Saccharomyces cerevisiae to identify enzymes involved in stereo-selective reductions of specific carbonyl compounds: an alternative to protein purification journal August 2003
Plasmids specifying ε-caprolactam degradation in Pseudomonas strains journal May 1984
Measurement of yeast intracellular pH by image processing and the change it undergoes during growth phase journal January 1995
Heterologous expression of the alcohol dehydrogenase (adhI) gene from Geobacillus thermoglucosidasius strain M10EXG journal June 2008
Biotechnological production of itaconic acid journal August 2001
The remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexes journal December 2001
Single point mutations in various domains of a plant plasma membrane H(+)-ATPase expressed in Saccharomyces cerevisiae increase H(+)-pumping and permit yeast growth at low pH. journal October 1996
Characterization of the ectoine biosynthesis genes of haloalkalotolerant obligate methanotroph “Methylomicrobium alcaliphilum 20Z” journal November 2005
Proline biosynthesis from L-ornithine in Clostridium sticklandii: purification of Δ1-pyrroline-5-carboxylate reductase, and sequence and expression of the encoding gene, proC journal April 1999
Analysis of optimality in natural and perturbed metabolic networks journal November 2002
New Insights into the Evolutionary Links Relating to the 3-Deoxy-D-arabino-heptulosonate 7-Phosphate Synthase Subfamilies journal January 2006
Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate:  Structural Bases of Dehydrogenation and Decarboxylation Reactions † , ‡ journal August 2004
One-step random mutagenesis by error-prone rolling circle amplification journal October 2004
L-Aspartase: New Tricks from an Old Enzyme book January 2000
Cloning and Nucleotide Sequence of the Alcohol Acetyltransferase II Gene ( ATF2 ) from Saccharomyces cerevisiae Kyokai No. 7 journal January 1998
Cloning and expression in Escherichia coli of the Clostridium thermoaceticum gene encoding thermostable formyltetrahydrofolate synthetase journal February 1988
Biotin in microbes, the genes involved in its biosynthesis, its biochemical role and perspectives for biotechnological production journal December 2002
3-Methylaspartate ammonia-lyase as a marker enzyme of the mesaconate pathway for ( S )-glutamate fermentation in Enterobacteriaceae journal December 1997
The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities journal May 2000
Production of Fumaric Acid in 20-Liter Fermentors journal January 1962
On the dehydration of ( R )-lactate in the fermentation of alanine to propionate by Clostridium propionicum journal June 1984
Crystallization and properties of aspartate aminotransferase from escherichia coli B journal April 1979
Acryloyl-CoA reductase from Clostridium propionicum: An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein journal March 2003
Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum journal January 2006
Metabolic Engineering of Escherichia coli for Enhanced Production of Succinic Acid, Based on Genome Comparison and In Silico Gene Knockout Simulation journal December 2005
Genetic Analysis of a Gene Cluster for Cyclohexanol Oxidation in Acinetobacter sp. Strain SE19 by In Vitro Transposition journal September 2000
Escherichia coli YqhD Exhibits Aldehyde Reductase Activity and Protects from the Harmful Effect of Lipid Peroxidation-derived Aldehydes journal January 2008
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of LysA (Rv1293) from Mycobacterium tuberculosis journal July 2005
Enzymatic evidence for an involvement of pyruvate dehydrogenase in the anaerobic glycerol metabolism of Klebsiella pneumoniae journal August 1997
Fumaric acid production by fermentation journal January 2008
Localization and characteristics of rat liver mitochondrial aldehyde dehydrogenases journal October 1976
Pyruvate decarboxylase from Kluyveromyces lactis: An enzyme with an extraordinary substrate activation behaviour journal July 2002
Regulation of Serine Biosynthesis in Arabidopsis: CRUCIAL ROLE OF PLASTIDIC 3-PHOSPHOGLYCERATE DEHYDROGENASE IN NON-PHOTOSYNTHETIC TISSUES journal January 1999
Reliable, Sensitive, Rapid and Quantitative Enzyme-Based Assay for Gamma-Hydroxybutyric Acid (GHB) journal January 2004
Identification and Characterization of the First Class of Potent Bacterial Acetyl-CoA Carboxylase Inhibitors with Antibacterial Activity journal April 2004
The physiological effects and metabolic alterations caused by the expression of Rhizobium etli pyruvate carboxylase in Escherichia coli journal July 2001
Purification, Properties and Immunological Relationship of l(+)-Lactate Dehydrogenase from Lactobacillus casei journal August 1976
Identification, cloning, purification, and enzymatic characterization of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase journal December 2002
Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD). journal January 1990
Construction of a synthetic YdbK-dependent pyruvate:H2 pathway in Escherichia coli BL21(DE3) journal May 2009
Staphylococcus haemolyticus contains two D-glutamic acid biosynthetic activities, a glutamate racemase and a D-amino acid transaminase. journal January 1995
Purification and Properties of NADH-Dependent 5,10-Methylenetetrahydrofolate Reductase (MetF) fromEscherichia coli journal February 1999
Two W-containing formate dehydrogenases (CO2-reductases) involved in syntrophic propionate oxidation by Syntrophobacter fumaroxidans journal June 2003
An enone reductase from Nicotiana tabacum: cDNA cloning, expression in Escherichia coli, and reduction of enones with the recombinant proteins journal February 2008
[61] Purification and properties of 5,10-methylenetetrahydrofolate reductase from Clostridium formicoaceticum book January 1986
Cloning of poly(3-hydroxybutyric acid) synthase genes of Rhodobacter sphaeroides and Rhodospirillum rubrum and heterologous expression in Alcaligenes eutrophus journal June 1992
Olefin Metathesis Involving Ruthenium Enoic Carbene Complexes journal October 2001
Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus journal March 2004
Purification and properties of the inducible coenzyme A-linked butyraldehyde dehydrogenase from Clostridium acetobutylicum. journal January 1988
Enzymatic synthesis of isoamyl acetate using immobilized lipase from Rhizomucor miehei journal May 2001
The Effects of Wall Populations on Coexistence of Bacteria in the Liquid Phase of Chemostat Cultures journal May 1985
Production of Multifunctional Organic Acids from Renewable Resources book January 1999
Functional genomics by NMR spectroscopy: Phenylacetate catabolism in Escherichia coli journal June 2003
The genome of Syntrophus aciditrophicus: Life at the thermodynamic limit of microbial growth journal April 2007
Induced Rebuilding of Aspartase Conformation journal November 1992
Discovery of Amide (Peptide) Bond Synthetic Activity in Acyl-CoA Synthetase journal February 2008
Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels journal April 1999
Carboxylation reaction catalyzed by 2-oxoglutarate:ferredoxin oxidoreductases from Hydrogenobacter thermophilus journal November 2009
Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1 journal February 2009
Corynebacterium glutamicum tailored for high-yield L-valine production journal May 2008
Cloning and Sequencing of the Gene Encoding the Soluble Fumarate Reductase from Saccharomyces cerevisiae journal January 1996
Two biochemically distinct classes of fumarase in Escherichia coli journal January 1988
Nucleotide sequence of the Escherichia coli gap gene. Different evolutionary behavior of the NAD+-binding domain and of the catalytic domain of D-glyceraldehyde-3-phosphate dehydrogenase journal July 1985
The binding of reduced nicotinamide adenine dinucleotide to citrate synthase of Escherichia coli K12 journal January 1976
DNA shuffling method for generating highly recombined genes and evolved enzymes journal April 2001
Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase. journal January 1987
Microbial synthesis of p‐hydroxybenzoic acid from glucose journal December 2001
A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic β-oxidation pathway: Anaerobic fatty acid degradation journal January 2003
Description and Interpretation of Adaptive Evolution of Escherichia coli K-12 MG1655 by Using a Genome-Scale In Silico Metabolic Model journal November 2003
Nitrate-Dependent Regulation of Acetate Biosynthesis and Nitrate Respiration by Clostridium thermoaceticum journal March 1999
Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase. : Heterologous expression of the gene from Sulfolobus sp. strain 7, and characterization of the recombinant and variant enzymes journal November 2001
Cloning, Expression and Characterization of a Thiolase Gene from Clostridium pasteurianum journal June 2006
Characterization of a gene cluster encoding the maleylacetate reductase from Ralstonia eutropha 335T, an enzyme recruited for growth with 4-fluorobenzoate journal February 2004
Studies on the Inactivation of Bovine Liver Enoyl-CoA Hydratase by (Methylenecyclopropyl)formyl-CoA:  Elucidation of the Inactivation Mechanism and Identification of Cysteine-114 as the Entrapped Nucleophile journal October 2001
Primary Structure and Tissue-specific Expression of Human β-Hydroxyisobutyryl-coenzyme A Hydrolase journal October 1996
Cloning and expression in Escherichia coli of the gene for 10-formyltetrahydrofolate synthetase from Clostridium acidiurici ("Clostridium acidi-urici"). journal January 1986
Sequence and analysis of the citrulline biosynthetic operon argC-F from Bacillus subtilis journal May 1994
Purification, characterization, and immunological properties of fumarase from Euglena gracilis var. bacillaris. journal January 1985
Guerbet condensation of methanol with n-propanol to isobutyl alcohol over heterogeneous copper chromite/Mg–Al mixed oxides catalysts journal October 2004
Alteration of substrate specificity of aspartase by directed evolution journal June 2005
Homology between hydroxybutyryl and hydroxyacyl coenzyme A dehydrogenase enzymes from Clostridium acetobutylicum fermentation and vertebrate fatty acid beta-oxidation pathways. journal January 1989
Stabilization of pet operon plasmids and ethanol production in Escherichia coli strains lacking lactate dehydrogenase and pyruvate formate-lyase activities. journal January 1996
Expression of Pyruvate Carboxylase Enhances Succinate Production in Escherichia coli without Affecting Glucose Uptake journal August 1998
Kinetic mechanism of Escherichia coli isocitrate dehydrogenase and its inhibition by glyoxylate and oxaloacetate journal March 1986
Electrotransformation of Clostridium thermocellum journal February 2004
Redistribution of Metabolic Fluxes inEscherichia coliwith Fermentative Lactate Dehydrogenase Overexpression and Deletion journal April 1999
New Reactions in the Crotonase Superfamily:  Structure of Methylmalonyl CoA Decarboxylase from Escherichia coli † , ‡ journal April 2000
Strain engineering for stereoselective bioreduction of dicarbonyl compounds by yeast reductases journal April 2005
Cloning, Sequencing, Expression, and Insertional Inactivation of the Gene for the Large Subunit of the Coenzyme B 12 -dependent Isobutyryl-CoA Mutase from Streptomyces cinnamonensis journal March 1998
Studies on rat brain acyl-coenzyme A hydrolase (short chain) journal August 1976
Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase journal November 2003
Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae journal December 1989
Autolytic Activity and Butanol Tolerance of Clostridium acetobutylicum journal January 1982
Expression of a cytoplasmic transhydrogenase inSaccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool journal January 2000
3-Hydroxypropionyl-Coenzyme A Synthetase from Metallosphaera sedula, an Enzyme Involved in Autotrophic CO2 Fixation journal December 2007
Imbalance of leucine flux in Lactococcus lactis and its use for the isolation of diacetyl-overproducing strains. journal January 1996
Combinatorial protein engineering by incremental truncation journal March 1999
A Comparison of Lipid Patterns in Photosynthesizing and Nonphotosynthesizing Cells of Euglena Gracilis * journal September 1963
The Role of Pyruvate Ferredoxin Oxidoreductase in Pyruvate Synthesis during Autotrophic Growth by the Wood-Ljungdahl Pathway journal June 2000
A literature network of human genes for high-throughput analysis of gene expression journal May 2001
A new logic for DNA engineering using recombination in Escherichia coli journal October 1998
Discovering New Enzymes and Metabolic Pathways:  Conversion of Succinate to Propionate by Escherichia coli † journal April 2000
Acetone-butanol fermentation revisited. journal January 1986
Cis,cis-Muconate Lactonizing Enzyme from Trichosporon cutaneum: Evidence for a Novel Class of Cycloisomerases in Eucaryotes journal February 1994
Purification and properties of a nicotinamide adenine dinucleotide-linked cyclohexanol dehydrogenase from aNocardia species journal January 1980
Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli journal July 2007
Alteration of a single amino acid changes the substrate specificity of dihydroflavonol 4-reductase: Substrate specificity of DFR journal February 2001
Studies of the Hyperthermophile Thermotoga maritima by Random Sequencing of cDNA and Genomic Libraries journal June 1993
Insight into the Mechanism of the B 12 -Independent Glycerol Dehydratase from Clostridium butyricum :  Preliminary Biochemical and Structural Characterization ‡ journal April 2004
Glutamate Dehydrogenase Activity Can Be Transmitted Naturally to Lactococcus lactis Strains To Stimulate Amino Acid Conversion to Aroma Compounds journal February 2006
Purification and properties of dihydroxy acid dehydratase from soluble and mitochondrial fractions of Neurospora crassa journal May 1970
Structural and Kinetic Analysis of Catalysis by a Thiamin Diphosphate-Dependent Enzyme, Benzoylformate Decarboxylase † journal February 2003
Metabolic Flux Analysis ofEscherichia coliDeficient in the Acetate Production Pathway and Expressing theBacillus subtilisAcetolactate Synthase journal January 1999
Accumulation of Poly[(R)-3-Hydroxyalkanoates] in Pseudomonas oleovorans during Growth with Octanoate in Continuous Culture at Different Dilution Rates journal August 2000
The IdhA Gene Encoding the Fermentative Lactate Dehydrogenase of Escherichia Coli journal January 1997
Diels–Alder reactions between cyclic five-membered dienes and acetylene journal August 2002
Purification, crystallization and preliminary crystallographic studies on 2-dehydro-3-deoxygalactarate aldolase from Leptospira interrogans journal November 2006
Novel Type of ADP-Forming Acetyl Coenzyme A Synthetase in Hyperthermophilic Archaea: Heterologous Expression and Characterization of Isoenzymes from the Sulfate Reducer Archaeoglobus fulgidus and the Methanogen Methanococcus jannaschii journal February 2002
Metabolically engineered bacteria for producing hydrogen via fermentation journal March 2008
Bioconversion of fumaric acid to succinic acid by recombinantE. coli journal March 1998
Properties of 2-hydroxyglutarate dehydrogenase from Fusobacterium. journal January 1986
Nucleotide sequence of Escherichia coli argB and argC genes: comparison of N-acetylglutamate kinase and N-acetylglutamate-γ-semialdehyde dehydrogenase with homologous and analogous enzymes journal September 1988
The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction journal June 1999
The Autotrophic Pathway of Acetate Synthesis in Acetogenic Bacteria journal October 1986
Waxmonoester fermentation in Euglena gracilis T. Factors favouring the synthesis of odd-numbered fatty acids and alcohols journal January 1985
GFP-labelled Rubisco and aspartate aminotransferase are present in plastid stromules and traffic between plastids journal January 2004
Molecular Properties and Enhancement of Thermostability by Random Mutagenesis of Glutamate Dehydrogenase from Bacillus subtilis journal January 2005
Autocatalytic activation of acetyl-CoA synthase journal March 2004
Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Purification and Characterization of 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase journal January 2002
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids journal June 2003
Mimicking Somatic Hypermutation: Affinity Maturation of Antibodies Displayed on Bacteriophage Using a Bacterial Mutator Strain journal July 1996
Characterization of the last step of the aerobic phenylacetic acid degradation pathway journal February 2007
Microbial CO Conversions with Applications in Synthesis Gas Purification and Bio-Desulfurization journal January 2006
Characterization of the sol Operon in Butanol-Hyperproducing Clostridium saccharoperbutylacetonicum Strain N1-4 and Its Degeneration Mechanism journal January 2007
The Exon-Intron Organization of the Genes (GAD1 and GAD2) Encoding Two Human Glutamate Decarboxylases (GAD67 and GAD65) Suggests That They Derive from a Common Ancestral GAD journal May 1994
The NADPH-linked acetoacetyl-CoA reductase from Zoogloea ramigera. Characterization and mechanistic studies of the cloned enzyme over-produced in Escherichia coli journal May 1988
A role for pabAB, a p-aminobenzoate synthase gene of Streptomyces venezuelae ISP5230, in chloramphenicol biosynthesis journal June 1996
Ethanol production during batch fermentation with Saccharomyces cerevisiae: changes in glycolytic enzymes and internal pH. journal January 1987
Evolution of Function in the Crotonase Superfamily:  The Stereochemical Course of the Reaction Catalyzed by 2-Ketocyclohexanecarboxyl-CoA Hydrolase journal June 2004
Development of a Combined Biological and Chemical Process for Production of Industrial Aromatics from Renewable Resources journal October 2007
Characterization, Sequencing, and Expression of the Genes Encoding a Reactivating Factor for Glycerol-inactivated Adenosylcobalamin-dependent Diol Dehydratase journal December 1997
Biocatalytic deuterium- and hydrogen-transfer using over-expressed ADH-‘A’: enhanced stereoselectivity and 2 H-labeled chiral alcohols journal January 2006
Gene Cloning and Characterization of Maleatecis-transIsomerase fromAlcaligenes faecalis journal October 1997
An unconventional pathway for reduction of CO2 to methane in CO-grown Methanosarcina acetivorans revealed by proteomics journal November 2006
Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms journal August 2005
Insights into the Evolution of Allosteric Properties. The NADH Binding Site of Hexameric Type II Citrate Synthases † , ‡ journal May 2003
Effect of different levels of NADH availability on metabolic fluxes of Escherichia coli chemostat cultures in defined medium journal June 2005
Ester Formation by Alcohol Acetyltransferase from Brewers’ Yeast journal October 1981
A new approach to directed gene evolution by recombined extension on truncated templates (RETT) journal December 2003
Purification of Pseudomonas putida acyl coenzyme A ligase active with a range of aliphatic and aromatic substrates. journal January 1993
Mammalian Wax Biosynthesis: II. EXPRESSION CLONING OF WAX SYNTHASE cDNAs ENCODING A MEMBER OF THE ACYLTRANSFERASE ENZYME FAMILY journal June 2004
Isolation and characterization of a new succinic acid-producing bacterium, Mannheimia succiniciproducens MBEL55E, from bovine rumen journal April 2002
N-Acetylglutamate and its changing role through evolution journal June 2003
Metabolic modelling of microbes: the flux-balance approach journal March 2002
Leishmania major thialysine N ε -acetyltransferase: Identification of amino acid residues crucial for substrate binding journal September 2005
Identification and Characterization of Mitochondrial Acetyl-Coenzyme A Hydrolase from Pisum sativum L. Seedlings journal September 1990
The Genes for Anabolic 2-Oxoglutarate: Ferredoxin Oxidoreductase from Hydrogenobacter thermophilus TK-6 journal March 2001
A Shared Binding Site for NAD + and Coenzyme A in an Acetaldehyde Dehydrogenase Involved in Bacterial Degradation of Aromatic Compounds † journal July 2008
Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes journal July 2009
Structure and Mechanism of HpcH: A Metal Ion Dependent Class II Aldolase from the Homoprotocatechuate Degradation Pathway of Escherichia coli journal November 2007
Primary structure of the succinyl-CoA synthetase of Escherichia coli journal October 1985
Multiple metal-carbon bonds. 16. Tungsten-oxo alkylidene complexes as olefins metathesis catalysts and the crystal structure of W(O)(CHCMe3(PEt3)Cl2
  • Wengrovius, Jeffrey H.; Schrock, Richard R.; Churchill, Melvyn Rowen
  • Journal of the American Chemical Society, Vol. 102, Issue 13, p. 4515-4516 https://doi.org/10.1021/ja00533a035
journal June 1980
A Novel Putrescine Utilization Pathway Involves γ-Glutamylated Intermediates of Escherichia coli K-12 journal December 2004
Cloning, sequencing, and overexpression of the Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase (pckA) gene. journal January 1997
Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities journal January 2008
Acetoacetate metabolism in rat brain. Development of acetoacetyl-coenzyme A deacylase and 3-hydroxy-3-methylglutaryl-coenzyme A synthase journal December 1978
Role of Butyryl Phosphate in the Energy Metabolism of Clostridium Tetanomorphum journal January 1963
Activation of L-Lysine ε-Dehydrogenase from Agrobacterium tumefaciens by Several Amino Acids and Monocarboxylates journal July 1989
Metabolic flux analysis for succinic acid production by recombinantEscherichia coli with amplified malic enzyme activity journal January 2001
Characterization of a Fungal Maleylacetoacetate Isomerase Gene and Identification of Its Human Homologue journal January 1998
Investigation of the first step of biotin biosynthesis in Bacillus sphaericus. Purification and characterization of the pimeloyl-CoA synthase, and uptake of pimelate journal November 1992
A mutant D-amino acid aminotransferase with broad substrate specificity: construction by replacement of the interdomain loop Pro119- Arg120-Pro121 by Gly-Gly-Gly journal January 1998
Gene Site Saturation Mutagenesis: A Comprehensive Mutagenesis Approach book August 2004
Involvement of the cis/trans Isomerase Cti in Solvent Resistance of Pseudomonas putidaDOT-T1E journal September 1999
Purification of Active E1alpha2beta2 of Pseudomonas Putida Branched-Chain-Oxoacid Dehydrogenase journal November 1995
Characterization and Isolation of Enzymes that Hydrolyze Short-Chain acyl-CoA in Rat-Liver Mitochondria journal July 1996
Stereochemical and Isotopic Labeling Studies of 4-Oxalocrotonate Decarboxylase and Vinylpyruvate Hydratase: Analysis and Mechanistic Implications journal November 1994
Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1 journal February 1991
Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli journal April 2004
Characterization of the p -Coumaric Acid Decarboxylase from Lactobacillus plantarum CECT 748 T
  • Rodríguez, Héctor; Landete, José María; Curiel, José Antonio
  • Journal of Agricultural and Food Chemistry, Vol. 56, Issue 9 https://doi.org/10.1021/jf703779s
journal May 2008
Differential effects of ethanol and hexanol on the Escherichia coli cell envelope. journal January 1980
Cloning and Nucleotide Sequence of the Aspartase Gene of Pseudomonas fluorescens1 journal January 1986
Molecular properties of pyruvate formate-lyase activating enzyme journal December 1993
Degradation of chloroaromatics: purification and characterization of maleylacetate reductase from Pseudomonas sp. strain B13. journal January 1993
Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway journal April 1995
ω-Amino Acid:Pyruvate Transaminase from Alcaligenes denitrificans Y2k-2: a New Catalyst for Kinetic Resolution of β-Amino Acids and Amines journal April 2004
Styrene lower catabolic pathway in Pseudomonas fluorescens ST: identification and characterization of genes for phenylacetic acid degradation journal March 2007
Improved specificity toward substrates with positively charged side chains by site-directed mutagenesis of the L-lactate dehydrogenase of Bacillus stearothermophilus journal April 1995
Enzymatic reduction of benzoyl-CoA to alicyclic compounds, a key reaction in anaerobic aromatic metabolism journal April 1992
2-Ketocyclohexanecarboxyl Coenzyme A Hydrolase, the Ring Cleavage Enzyme Required for Anaerobic Benzoate Degradation byRhodopseudomonas palustris journal May 1998
The Structure of l -Aspartate Ammonia-Lyase from Escherichia coli † , ‡ journal July 1997
Location of the fadBA operon on the physical map of Escherichia coli. journal January 1991
The sodium ion translocating glutaconyl-CoA decarboxylase from Acidaminococcus fermentans: cloning and function of the genes forming a second operon journal January 1999
Construction of a brewer's yeast having α-acetolactate decarboxylase gene from Acetobacter aceti ssp. xylinum integrated in the genome journal February 1994
Radical-mediated dehydration reactions in anaerobic bacteria journal October 2005
Crystal Structure of E.coli Alcohol Dehydrogenase YqhD: Evidence of a Covalently Modified NADP Coenzyme journal September 2004
Dihydrolipoamide Dehydrogenase Mutation Alters the NADH Sensitivity of Pyruvate Dehydrogenase Complex of Escherichia coli K-12 journal March 2008
Cloning and Characterization of Helicobacter pylori Succinyl CoA:Acetoacetate CoA-transferase, a Novel Prokaryotic Member of the CoA-transferase Family journal October 1997
Effects of Substitution of Tryptophan 412 in the Substrate Activation Pathway of Yeast Pyruvate Decarboxylase † journal August 1999
Translation initiation in Escherichia coli: sequences within the ribosome-binding site journal May 1992
Demonstration of hydrogenase in extracts of the homoacetate-fermenting bacterium Clostridium thermoaceticum. journal January 1982
Characterization and Transcription of the Genes Encoding Enzymes Involved in Butyrate Production in Butyrivibrio fibrisolvens journal September 2003
Purification and properties of Escherichia coli coenzyme A-transferase journal November 1975
Stereochemistry of reduction of the endocyclic double bond of (−)-carvone with the enzyme preparation from cultured cells of Nicotiana tabacum journal January 1989
Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate journal January 2008
PAD1 encodes phenylacrylic acid decarboxylase which confers resistance to cinnamic acid in Saccharomyces cerevisiae journal May 1994
A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast journal March 2002
Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. introduction of a six-residue ion-pair network in the hinge region journal July 1998
Modulation of higher-plant NAD(H)-dependent glutamate dehydrogenase activity in transgenic tobacco via alteration of beta subunit levels journal April 2005
Cloning and expression of Clostridium acetobutylicum ATCC 824 acetoacetyl-coenzyme A:acetate/butyrate:coenzyme A-transferase in Escherichia coli. journal January 1990
Hydrolysis of Cyclic and Linear Oligomers of 6-Aminocaproic Acid by a Bacterial Cell Extract* journal June 1966
Unusual ADP-forming acetyl-coenzyme A synthetases from the mesophilic halophilic euryarchaeon Haloarcula marismortui and from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum journal August 2004
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate. journal January 1994
Life with CO or CO2 and H2 as a source of carbon and energy. journal February 1991
β-Lactam synthetase: A new biosynthetic enzyme journal August 1998
Novel NADP-linked alcohol–aldehyde/ketone oxidoreductase in thermophilic ethanologenic bacteria journal April 1981
Characterization and molecular properties of 2-oxoglutarate decarboxylase from Euglena gracilis journal July 1991
The Hotdog Thioesterase EntH (YbdB) Plays a Role In Vivo in Optimal Enterobactin Biosynthesis by Interacting with the ArCP Domain of EntB journal August 2007
Proton Abstraction Reaction, Steady-State Kinetics, and Oxidation−Reduction Potential of Human Glutaryl-CoA Dehydrogenase † journal September 2000
Substrate specificity of coenzyme B12-dependent diol dehydrase: Glycerol as both a good substrate and a potent inactivator journal March 1976
Acetate:Succinate CoA-transferase in the Hydrogenosomes of Trichomonas vaginalis : IDENTIFICATION AND CHARACTERIZATION journal November 2007
A Conserved Gene Cluster Rules Anaerobic Oxidative Degradation of l-Ornithine journal February 2009
Acetone-butanol-isopropanol production byClostridium beijerinckii (synonym,Clostridium butylicum) journal May 1986
Stereo- and regiospecific cis,cis -muconate cycloisomerization by Rhodococcus rhodochrous N75 journal July 2003
Itaconate biosynthesis in Aspergillus terreus. journal January 1995
Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster journal August 2001
Molecular and catalytic properties of the acetoacetyl-coenzyme A thiolase of Escherichia coli journal September 1976
Creating multiple-crossover DNA libraries independent of sequence identity journal September 2001
KEGG: Kyoto Encyclopedia of Genes and Genomes journal January 2000
Recovery of succinic acid produced by fermentation of a metabolically engineered Mannheimia succiniciproducens strain journal December 2007
A novel enzyme, citryl-CoA lyase, catalysing the second step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6 journal March 2004
Characterization of a corrinoid protein involved in the C1 metabolism of strict anaerobic bacterium Moorella thermoacetica journal January 2007
Searching sequence space by definably random mutagenesis: improving the catalytic potency of an enzyme. journal January 1990
Nondecarboxylating and Decarboxylating Isocitrate Dehydrogenases: Oxalosuccinate Reductase as an Ancestral Form of Isocitrate Dehydrogenase journal January 2008
[49] Fatty acid oxidation complex from Escherichia coli book January 1981
Routes of Flavodoxin and Ferredoxin Reduction in Escherichia coli: CoA-Acylating Pyruvate: Flavodoxin and NADPH: Flavodoxin Oxidoreductases Participating in the Activation of Pyruvate Formate-Lyase journal April 1982
Engineering a native homoethanol pathway in Escherichia coli B for ethanol production journal October 2007
[93] 2-Keto-3-deoxy-d-glucarate aldolase book January 1966
Organization and regulation of the Bacillus subtilis odhAB operon, which encodes two of the subenzymes of the 2-oxoglutarate dehydrogenase complex journal August 1992
Purification and characterization of a coenzyme-A-dependent succinate-semialdehyde dehydrogenase from Clostridium kluyveri journal February 1993
Threonine Deamination in Escherichia coli ii. journal January 1957
Purification and physical properties of inducible Escherichia coli lysine decarboxylase journal February 1974
Distribution of genes encoding the microbial non-oxidative reversible hydroxyarylic acid decarboxylases/phenol carboxylases☆ journal September 2005
MmcBC in Pelotomaculum thermopropionicum represents a novel group of prokaryotic fumarases journal May 2007
Metabolic engineering ofClostridium acetobutylicum ATCC 824 for increased solvent production by enhancement of acetone formation enzyme activities using a synthetic acetone operon journal November 1993
Batch culture characterization and metabolic flux analysis of succinate-producing Escherichia coli strains journal May 2006
Effect of oxygen on theEscherichia coli ArcA and FNR regulation systems and metabolic responses journal January 2005
Microbial synthesis of cis,cis-muconic acid by Sphingobacterium sp. GCG generated from effluent of a styrene monomer (SM) production plant journal December 2004
Globin Gene Server: A Prototype E-Mail Database Server Featuring Extensive Multiple Alignments and Data Compilation for Electronic Genetic Analysis journal May 1994
Dissecting the functional program of Escherichia coli promoters: the combined mode of action of Lac repressor and AraC activator journal September 2001
Whey Fermentation by Anaerobiospirillum succiniciproducens for Production of a Succinate-Based Animal Feed Additive journal May 1999
Clostridium cellulolyticum : model organism of mesophilic cellulolytic clostridia journal September 2005
Molecular Cloning, Sequencing, and Expression of the Genes Encoding Adenosylcobalamin-dependent Diol Dehydrase of Klebsiella oxytoca journal March 1995
Metabolic Engineering of Escherichia coli for Enhanced Production of (R)- and (S)-3-Hydroxybutyrate journal March 2009
Recombination and chimeragenesis by in vitro heteroduplex formation and in vivo repair journal September 1999
Characterization of two 3-ketothiolases possessing differing substrate specificities in the polyhydroxyalkanoate synthesizing organism Alcaligenes eutrophus journal July 1988
Gene Cloning, Transcriptional Analysis, Purification, and Characterization of Phenolic Acid Decarboxylase from Bacillus subtilis journal April 1998
Identification, Cloning, and Characterization of a Lactococcus lactis Branched-Chain  -Keto Acid Decarboxylase Involved in Flavor Formation journal January 2005
Life with Carbon Monoxide journal January 2004
Growth ofRhodospirillum rubrum on synthesis gas: Conversion of CO to H2 and poly-β-hydroxyalkanoate journal January 2007
In Vitro Conversion of Propionate to Pyruvate by Salmonella enterica Enzymes:  2-Methylcitrate Dehydratase (PrpD) and Aconitase Enzymes Catalyze the Conversion of 2-Methylcitrate to 2-Methylisocitrate † journal April 2001
Directed Evolution of Pyruvate Decarboxylase-Negative Saccharomyces cerevisiae, Yielding a C2-Independent, Glucose-Tolerant, and Pyruvate-Hyperproducing Yeast journal January 2004
Aspartate: 2-Oxoglutarate Aminotransferase from Bakers' Yeast: Crystallization and Characterization1 journal January 1982
Domain Structure Characterization of the Multifunctional α-Aminoadipate Reductase from Penicillium chrysogenum by Limited Proteolysis: ACTIVATION OF α-AMINOADIPATE DOES NOT REQUIRE THE PEPTIDYL CARRIER PROTEIN BOX OR THE REDUCTION DOMAIN journal December 2002
Volatile Ketone Formation in Bacteria: Release of 3-Oxopentanoate by Soil Pseudomonads During Growth on Heptanoate journal April 2001

Similar Records

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY