An improved and facile method for the synthesis of 1,1-bis(4-hydroxyphenyl)-2-phenylethylene and its derivatives
- Argonne National Lab., IL (United States)
- Univ. of Chicago, IL (United States)
The synthesis of 1,1-bis(4-hydroxyphenyl)-2-phenylethylene, which is of biological interest, has been reported by several authors in the past. In this article an improved method is introduced. Different (and commercially available) starting materials are adopted. Also a protective group which is easily attached and removed is used. This procedure provides milder reaction conditions and better yields while the number of steps involved in the synthesis of the compound are reduced. Furthermore, the reactions are clean and formation of byproducts which lead to poorer yields are avoided.
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States); Department of Health and Human Services, Washington, DC (United States)
- DOE Contract Number:
- W-31109-ENG-38
- OSTI ID:
- 10188496
- Report Number(s):
- ANL/CHM/PP-75382; ON: DE95001125; TRN: 94:021080
- Resource Relation:
- Other Information: PBD: [1994]
- Country of Publication:
- United States
- Language:
- English
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