The study of human mutation rates. Progress report, 1989--1992

Technical Report · Tue Dec 01 00:00:00 EST 1992

DOI:https://doi.org/10.2172/10188260· OSTI ID:10188260

Neel, J V

We will describe recent developments regarding the question of induced mutations in the survivors of the atomic bombings of Hiroshima and Nagasaki. As part of that work we, describe some developments with respect to the Amerindian blood samples collected under DoE sponsorship between 1964 and 1982. Then developments regarding the application of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) to the study of genetic variation and mutation affecting protein characteristics. In particular, we will report on the identification and isolation of genes of especial interest as reflected in the behavior of the proteins which they encode.

• Research Organization: Univ. of Michigan, Ann Arbor, MI (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: FG02-87ER60533
• OSTI ID: 10188260
• Report Number(s): DOE/ER/60533-5; ON: DE93003658
• Resource Relation: Other Information: PBD: [1992]
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
MUTATION FREQUENCY
AMERICAN INDIANS
GENETIC VARIABILITY
GENE MUTATIONS
GLOBULINS
MAN
A-BOMB SURVIVORS
GENETIC RADIATION EFFECTS
RISK ASSESSMENT
BLOOD SERUM
VIRAL DISEASES
HEREDITARY DISEASES
ELECTROPHORESIS
HYDROXYLASES
AMINO ACID SEQUENCE
PHOSPHOTRANSFERASES
PHOSPHORUS 32
NUCLEOPROTEINS
PROTEIN STRUCTURE
PROGRESS REPORT
560151
560161
550400
550201
GENETICS
TRACER TECHNIQUES