Capillary liquid chromatography using laser-based and mass spectrometric detection. Final technical progress report, September 1, 1989--January 31, 1993

Technical Report · Tue Sep 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/10182289· OSTI ID:10182289

Sepaniak, M J; Cook, K D

In the years following the 1986 seminal paper (J. Chromatogr. Sci., 24, 347-352) describing modern capillary zone electrophoresis (CZE), the prominence of capillary electrokinetic separation techniques has grown. A related electrochromatographic technique is micellar electrokinetic capillary chromatography (MECC). This report presents a brief synopsis of research efforts during the current 3-year period. In addition to a description of analytical separations-based research, results of efforts to develop and expand spectrometric detection for the techniques is reviewed. Laser fluorometric detection schemes have been successfully advanced. Mass spectrometric research was less fruitful, largely owing to personnel limitations. A regenerable fiber optic sensor was developed that can be used to remotely monitor chemical carcinogens, etc. (DLC)

• Research Organization: Tennessee Univ., Knoxville, TN (United States). Dept. of Chemistry
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: FG05-86ER13613
• OSTI ID: 10182289
• Report Number(s): DOE/ER/13613-36; ON: DE92040524
• Resource Relation: Other Information: PBD: [1992]
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
ELECTROPHORESIS
OPTIMIZATION
FULLERENES
LIQUID COLUMN CHROMATOGRAPHY
POLYCYCLIC AROMATIC HYDROCARBONS
PROGRESS REPORT
CAPILLARY FLOW
LASER SPECTROSCOPY
MICELLAR SYSTEMS
IMMUNOASSAY
OPTICAL FIBERS
ANTIBODIES
FLUORESCENCE SPECTROSCOPY
DERIVATIZATION
CHEMILUMINESCENCE
400105
550200
SEPARATION PROCEDURES
BIOCHEMISTRY