The antibody approach of labeling blood cells

Conference · Thu Dec 31 00:00:00 EST 1992

OSTI ID:10135987

Srivastava, S C

Although the science of blood cell labeling using monoclonal antibodies directed against specific cellular antigens is still in its early stages, considerable progress has recently been accomplished in this area. The monoclonal antibody approach offers the promise of greater selectivity and enhanced convenience since specific cell types can be labeled in vivo, thus eliminating the need for complex and damaging cell separation procedures. This article focuses on these developments with primary emphasis on antibody labeling of platelets and leukocytes. The advantages and the shortcomings of the recently reported techniques are critically assessed and evaluated.

• Research Organization: Brookhaven National Lab., Upton, NY (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 10135987
• Report Number(s): BNL-60145; CONF-9211111-1; ON: DE94008877; TRN: 94:007442
• Resource Relation: Conference: 6. international symposium on radiolabeled blood elements,Barcelona (Spain),23-27 Nov 1992; Other Information: PBD: [1992]
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
BLOOD PLATELETS
LABELLING
LEUKOCYTES
MONOCLONAL ANTIBODIES
TECHNETIUM 99
IODINE 123
GLYCOPROTEINS
550601
550301
UNSEALED RADIONUCLIDES IN DIAGNOSTICS
TRACER TECHNIQUES