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Title: [Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report

Abstract

Studies described herein sought and to synthesize PAH-adducted residues of DNA to serve as models for carrying out the mass spectrometric studies; to construct and test a high performance, pulsed ion bombardment, time-of-flight (TOF) mass spectrometer; to initiate an investigation of the efficacy of using thin wire sample holders to increase sensitivity and focused ion beam bombardment to increase ion yield and ion transmission; and to initiate an investigation of sensitivity enhancing matrices for PAH-adducted DNA.

Authors:
Publication Date:
Research Org.:
Oregon State Univ., Corvallis, OR (United States). Dept. of Agricultural Chemistry
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
10112374
Report Number(s):
DOE/ER/60696-5
ON: DE94004850; BR: HA0204030/KP0102000
DOE Contract Number:  
FG06-88ER60696
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: [1992]
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; DNA ADDUCTS; MASS SPECTROSCOPY; MASS SPECTROMETERS; DESIGN; BENZOPYRENE; CHRYSENE; LIQUID COLUMN CHROMATOGRAPHY; EPOXIDES; TIME-OF-FLIGHT METHOD; PROGRESS REPORT; 560300; 400102; CHEMICALS METABOLISM AND TOXICOLOGY; CHEMICAL AND SPECTRAL PROCEDURES

Citation Formats

Barofsky, D F. [Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report. United States: N. p., 1992. Web. doi:10.2172/10112374.
Barofsky, D F. [Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report. United States. https://doi.org/10.2172/10112374
Barofsky, D F. 1992. "[Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report". United States. https://doi.org/10.2172/10112374. https://www.osti.gov/servlets/purl/10112374.
@article{osti_10112374,
title = {[Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report},
author = {Barofsky, D F},
abstractNote = {Studies described herein sought and to synthesize PAH-adducted residues of DNA to serve as models for carrying out the mass spectrometric studies; to construct and test a high performance, pulsed ion bombardment, time-of-flight (TOF) mass spectrometer; to initiate an investigation of the efficacy of using thin wire sample holders to increase sensitivity and focused ion beam bombardment to increase ion yield and ion transmission; and to initiate an investigation of sensitivity enhancing matrices for PAH-adducted DNA.},
doi = {10.2172/10112374},
url = {https://www.osti.gov/biblio/10112374}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Dec 31 00:00:00 EST 1992},
month = {Thu Dec 31 00:00:00 EST 1992}
}