Electromagnetic imaging of dynamic brain activity

Conference · Tue Dec 31 00:00:00 EST 1991

DOI:https://doi.org/10.1109/NSSMIC.1991.259314· OSTI ID:10110191

Mosher, J; Leahy, R ^[1]; Lewis, P; Lewine, J; George, J ^[2]; Singh, M ^[3]

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1. University of Southern California, Los Angeles, CA (United States). Dept. of Electrical Engineering
2. Los Alamos National Lab., NM (United States)
3. University of Southern California, Los Angeles, CA (United States). Dept. of Radiology

Neural activity in the brain produces weak dynamic electromagnetic fields that can be measured by an array of sensors. Using a spatio-temporal modeling framework, we have developed a new approach to localization of multiple neural sources. This approach is based on the MUSIC algorithm originally developed for estimating the direction of arrival of signals impinging on a sensor array. We present applications of this technique to magnetic field measurements of a phantom and of a human evoked somatosensory response. The results of the somatosensory localization are mapped onto the brain anatomy obtained from magnetic resonance images.

• Research Organization: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States); University of Southern California, Los Angeles, CA (United States)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 10110191
• Report Number(s): LA-UR-91-3870; CONF-911106-56; ON: DE92005017
• Resource Relation: Conference: 1991 Institute of Electrical and Electronic Engineers (IEEE) nuclear science symposium and medical imaging conference,Santa Fe, NM (United States),2-9 Nov 1991; Other Information: PBD: [1991]
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BRAIN
IMAGES
MAGNETIC RESONANCE
BIOCHEMISTRY
ALGORITHMS
IMAGE PROCESSING
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