Synthesis and characterization of mesostructured silicas and gold frameworks as active matrices for biomolecule encapsulation.

Conference · Sun Jan 01 00:00:00 EST 2006 · Adv. Sci. Technol.

DOI:https://doi.org/10.4028/www.scientific.net/AST.51.30· OSTI ID:971451

Iton, L E; Crisci, A J; Vajdova, V; Laible, P D; Burns, C T; Firestone, M A

Interfacing of biomolecules to inorganic frameworks is essential for fabricating robust, functionally integrated biocomposites that may prove useful in a wide range of technologies including biocatalysis, biosensors or protein-based devices. Our work is directed at developing means to integrate biomolecules into mesostructured inorganics. These frameworks serve to both improve the mechanical stability of the proteins and to facilitate communication with them. Toward that end, we have synthesized and characterized mesoporous silicas and conductive metallic frameworks and have examined the encapsulation of both soluble (cytochrome c) and membrane proteins (bacteriorhodpsin) within them.

• Research Organization: Argonne National Lab. (ANL), Argonne, IL (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: DE-AC02-06CH11357
• OSTI ID: 971451
• Report Number(s): ANL/MSD/CP-119428; TRN: US201004%%156
• Journal Information: Adv. Sci. Technol., Vol. 51, Issue 2006; Conference: 11th International Ceramic Congress and 4th Forum on New Materials (CIMTEC 2006); Jun. 4, 2006 - Jun. 9, 2006; Acireale, Sicily, Italy
• Country of Publication: United States
• Language: ENGLISH

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
CERAMICS
COMMUNICATIONS
ENCAPSULATION
GOLD
MATRICES
MEMBRANE PROTEINS
PROTEINS
STABILITY
SYNTHESIS