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Title: Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures

Abstract

This manuscript highlights research focused on the development of field-deployable analytical instruments based on EC detection. Background information and a general overview of EC detection methods and integrated use of nanomaterials in the development of these sensors are provided. New developments in EC sensors using various types of screen-printed electrodes, integrated nanomaterials, and immunoassays are discussed. Recent applications of EC sensors for assessing exposure to pesticides or detecting biomarkers of disease are highlighted to demonstrate the ability to monitor chemical metabolites, enzyme activity, or protein biomarkers of disease. In addition, future considerations and opportunities for advancing the use of EC platforms for dosimetric studies are covered.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
Sponsoring Org.:
USDOE
OSTI Identifier:
949062
Report Number(s):
PNNL-SA-59427
24822; 400412000; TRN: US200907%%383
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article
Journal Name:
Journal of Exposure Science and Environmental Epidemiology, 19:1-18
Additional Journal Information:
Journal Volume: 19
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; DETECTION; DISEASES; ELECTRODES; ENZYME ACTIVITY; METABOLITES; MONITORS; PESTICIDES; PROTEINS; biomonitoring, dosimetry, electrochemical sensors, exposure assessment; Environmental Molecular Sciences Laboratory

Citation Formats

Barry, Richard C, Lin, Yuehe, Wang, Jun, Liu, Guodong, and Timchalk, Charles. Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures. United States: N. p., 2009. Web. doi:10.1038/jes.2008.71.
Barry, Richard C, Lin, Yuehe, Wang, Jun, Liu, Guodong, & Timchalk, Charles. Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures. United States. https://doi.org/10.1038/jes.2008.71
Barry, Richard C, Lin, Yuehe, Wang, Jun, Liu, Guodong, and Timchalk, Charles. 2009. "Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures". United States. https://doi.org/10.1038/jes.2008.71.
@article{osti_949062,
title = {Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures},
author = {Barry, Richard C and Lin, Yuehe and Wang, Jun and Liu, Guodong and Timchalk, Charles},
abstractNote = {This manuscript highlights research focused on the development of field-deployable analytical instruments based on EC detection. Background information and a general overview of EC detection methods and integrated use of nanomaterials in the development of these sensors are provided. New developments in EC sensors using various types of screen-printed electrodes, integrated nanomaterials, and immunoassays are discussed. Recent applications of EC sensors for assessing exposure to pesticides or detecting biomarkers of disease are highlighted to demonstrate the ability to monitor chemical metabolites, enzyme activity, or protein biomarkers of disease. In addition, future considerations and opportunities for advancing the use of EC platforms for dosimetric studies are covered.},
doi = {10.1038/jes.2008.71},
url = {https://www.osti.gov/biblio/949062}, journal = {Journal of Exposure Science and Environmental Epidemiology, 19:1-18},
number = ,
volume = 19,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 2009},
month = {Thu Jan 01 00:00:00 EST 2009}
}