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Title: Ultrasensitive Electrochemical Detection of mRNA Using Branched DNA Amplifiers

Journal Article · · Electrochemistry Communications, 10(12):1847-1850

We describe here an ultrasensitive electrochemical detection of m RNA protocol without RNA purification and PCR amplification. The new m RNA electrical detection capability is coupled to the amplification feature of branched DNA (bDNA) technology and with the nagnetic beads based electrochemical bioassay.

Research Organization:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
OSTI ID:
946365
Report Number(s):
PNNL-SA-62748; TRN: US200903%%391
Journal Information:
Electrochemistry Communications, 10(12):1847-1850, Vol. 10, Issue 12; ISSN 1388-2481
Country of Publication:
United States
Language:
English