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Title: Structural properties of the histidine-containing loop in HIV-1RNase H

Journal Article · · Biophysical Chemistry
OSTI ID:892204

The isolated HIV-1 RNase H domain is inactive. This inactivity has been linked to the lack of structure in the C-terminus of the isolated domain. His539 residing in a loop preceding the C-terminal Helix was studies by NMR to determine the stability and conformational properties of this region.

Research Organization:
COLLABORATION - AstraZenecaBoston
DOE Contract Number:
DE-AC02-05CH11231
OSTI ID:
892204
Report Number(s):
LBNL-51093; BICIAZ; R&D Project: 864P1B; BnR: 400412000; TRN: US200622%%778
Journal Information:
Biophysical Chemistry, Vol. 96, Issue 1; Related Information: Journal Publication Date: 2002; ISSN 0301-4622
Country of Publication:
United States
Language:
English

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