skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Verification of the HRQAR two-dimensional approach for NCT microdosimetry

Journal Article · · Transactions of the American Nuclear Society
OSTI ID:89056
 [1]; ;
  1. Massachusetts Institute of Technology, Cambridge, MA (United States)

A unique approach to the microdosimetry of neutron capture therapy (NCT), which combines the high-resolution quantitative autoradiography (HRQAR) technique, and two-dimensional (2-D) Monte Carlo methods, has been developed by our group. Using this approach, actual cell morphology (ie., cell nuclei and cytoplasm structures) and microdistribution of the capture element (e.g., {sup 10}B) can be obtained; therefore, microdosimetry can be carried out without making any assumptions regarding either cell architecture or {sup 10}B distribution. This paper shows that results obtained by this 2-D approach are equivalent to the {open_quotes}traditional{close_quotes} 3-D approach.

OSTI ID:
89056
Report Number(s):
CONF-941102-; ISSN 0003-018X; TRN: 95:004215-0126
Journal Information:
Transactions of the American Nuclear Society, Vol. 71; Conference: Winter meeting of the American Nuclear Society (ANS), Washington, DC (United States), 13-18 Nov 1994; Other Information: PBD: 1994
Country of Publication:
United States
Language:
English