Advances in Proteomics Data Analysis and Display Using an Accurate Mass and Time Tag Approach
Proteomics, and the larger field of systems biology, have recently demonstrated utility in both the understanding of cellular processes on the molecular level and the identification of potential biomarkers of various disease states. The large amount of data generated by utilizing high mass accuracy mass spectrometry for high-throughput proteomics analyses presents a challenge in data processing, analysis and display. This review focuses on recent advances in nanoLC-FTICR-MS-based proteomics analysis and the accompanying data processing tools that have been developed in order to interpret and display the large volumes of data produced.
- Research Organization:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 878246
- Report Number(s):
- PNNL-SA-43136; 17797; 400412000; TRN: US200613%%118
- Journal Information:
- Mass Spectrometry Reviews, Vol. 25, Issue 3
- Country of Publication:
- United States
- Language:
- English
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