Peptide identification via constrained multi-objective optimization: Pareto-based genetic algorithms
Journal Article
·
· Concurrency and Computation. Practice & Experience
Automatic data-base independent peptide identification from collision-induced dissociation tandem mass spectrometry data is made difficult by large plateaus in the fitness landscapes of scoring functions and the fuzzy nature of the constraints that is due to noise in the data. Two different scoring functions are combined into a parallel multi-objective optimization framework.
- Research Organization:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 876881
- Report Number(s):
- PNNL-SA-42966; 2190; 9603; 3550; KP1102010; TRN: US200608%%84
- Journal Information:
- Concurrency and Computation. Practice & Experience, Vol. 17, Issue 14
- Country of Publication:
- United States
- Language:
- English
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