The human homologue of the retroviral oncogene qin maps to chromosome 14q13

Journal Article · Tue Apr 26 00:00:00 EDT 1994 · Proceedings of the National Academy of Sciences of the United States of America

DOI:https://doi.org/10.1073/pnas.91.9.3616· OSTI ID:86514

Kastury, K; Druck, T; Croce, C M; Huebner, K ^[1]; Li, Jian; Vogt, P K ^[2]; Su, Heyun ^[3]

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1. Jefferson Medical College, Philadelphia, PA (United States)
2. Scripps Research Institute, La Jolla, CA (United States)
3. Univ. of California, San Diego, La Jolla, CA (United States)

Chromosomal mapping of the human QIN gene (renamed FKH2 by the Human Genome Organization Nomenclature Committee) was initially accomplished by correlation of the presence of the QIN locus with specific chromosome regions in a rodent-human hybrid panel. This analysis revealed that the human QIN gene maps to chromosome region 14q11.2{yields}14q32, between the TCR and IGH loci. Further analysis by fluorescence in situ hybridization techniques with a human QIN genomic clone refined the human QIN gene localization to 14q13. 20 refs., 4 figs.

• Sponsoring Organization: USDOE
• OSTI ID: 86514
• Journal Information: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 9; Other Information: PBD: 26 Apr 1994
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
TRANSCRIPTION FACTORS
GENES
HUMAN CHROMOSOME 14
GENETIC MAPPING
DNA HYBRIDIZATION