Corrections for the effects of accidental coincidences, Compton scatter, and object size in positron emission mammography (PEM) imaging
Positron emission mammography (PEM) has begun to show promise as an effective method for the detection of breast lesions. Due to its utilization of tumor-avid radiopharmaceuticals labeled with positron-emitting radionuclides, this technique may be especially useful in imaging of women with radiodense or fibrocystic breasts. While the use of these radiotracers affords PEM unique capabilities, it also introduces some limitations. Specifically, acceptance of accidental and Compton-scattered coincidence events can decrease lesion detectability. The authors studied the effect of accidental coincidence events on PEM images produced by the presence of 18F-Fluorodeoxyglucose in the organs of a subject using an anthropomorphic phantom. A delayed-coincidence technique was tested as a method for correcting PEM images for the occurrence of accidental events. Also, a Compton scatter correction algorithm designed specifically for PEM was developed and tested using a compressed breast phantom.
- Research Organization:
- Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)
- Sponsoring Organization:
- USDOE Office of Energy Research (ER) (US)
- DOE Contract Number:
- AC05-84ER40150
- OSTI ID:
- 834834
- Report Number(s):
- JLAB-PHY-01-79; DOE/ER/40150-2999; IETNAE; TRN: US0407348
- Journal Information:
- IEEE Transactions on Nuclear Science, Vol. 48, Issue 3; Other Information: IEEE Transactions on Nuclear Science, Volume 48, Issue 3, Page(s) 913 - 923; PBD: 1 Jun 2001; ISSN 0018-9499
- Country of Publication:
- United States
- Language:
- English
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