Introductory Remarks on Effects of Dose and Radiation Quality in Relation to Non-Targeted Effects
It is now agreed that both high and low LET radiation can produce significant effects in cells which were not directly hit by the radiation. The effect predominates at low doses and seems to be already saturated at the lowest doses used by many investigators. Several methods have been used to explore the effect including very low fluences of alpha particles, microbeam technology and simple medium transfer. While the phenomenon is now recognized, very little is understood of the mechanisms involved and of the possible consequences or opportunities for radiation risk assessment and radiotherapy of this process. For this reason we think it is timely to propose to hold a workshop in the near future to explore the implications of the work in this field.
- Research Organization:
- Gray Laboratory Cancer Research Trust, Northwood (GB)
- Sponsoring Organization:
- USDOE Office of Environmental Management (EM) (US)
- OSTI ID:
- 833765
- Resource Relation:
- Conference: Lh Gray Workshop on the Mechanisms of Radiation Induced Bystander Effects, Dublin (IR), 12/03/2000--12/05/2000; Other Information: PBD: 3 Dec 2000
- Country of Publication:
- United States
- Language:
- English
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