Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing
- Genmark Inc., Salt Lake City, UT (United States)
- Virginia Polytechnic Institute and State Univ., Blacksburg, VA (United States)
We have exploited {open_quotes}progeny testing{close_quotes} to map quantitative trait loci (QTL) underlying the genetic variation of milk production in a selected dairy cattle population. A total of 1,518 sires, with progeny tests based on the milking performances of >150,000 daughters jointly, was genotyped for 159 autosomal microsatellites bracketing 1645 centimorgan or approximately two thirds of the bovine genome. Using a maximum likelihood multilocus linkage analysis accounting for variance heterogeneity of the phenotypes, we identified five chromosomes giving very strong evidence (LOD score {ge} 3) for the presence of a QTL controlling milk production: chromosomes 1, 6, 9, 10 and 20. These findings demonstrate that loci with considerable effects on milk production are still segregating in highly selected populations and pave the way toward marker-assisted selection in dairy cattle breeding. 44 refs., 4 figs., 3 tabs.
- OSTI ID:
- 79437
- Journal Information:
- Genetics, Vol. 139, Issue 2; Other Information: PBD: Feb 1995
- Country of Publication:
- United States
- Language:
- English
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