High-Current Experiments for Accelerator-Based Neutron Capture Therapy Applications
Several accelerator-based neutron capture therapy applications are under development. These applications include boron neutron capture therapy for glioblastoma multiform and boron neutron capture synovectomy (BNCS) for rheumatoid arthritis. These modalities use accelerator-based charged-particle reactions to create a suitable neutron source. Neutrons are produced using a high-current, 2-MV terminal tandem accelerator. For these applications to be feasible, high accelerator beam currents must be routinely achievable. An effort was undertaken to explore the operating regime of the accelerator in the milliampere range. In preparation for high-current operation of the accelerator, computer simulations of charged-particle beam optics were performed to establish high-current operating conditions. Herein we describe high beam current simulations and high beam current operation of the accelerator.
- Research Organization:
- Massachusetts Institute of Technology, Cambridge, MA (US); New Scientific, Inc., Cambridge, MA (US)
- Sponsoring Organization:
- None (US)
- OSTI ID:
- 786618
- Report Number(s):
- ISSN 0003-018X; CODEN TANSAO; ISSN 0003-018X; CODEN TANSAO; TRN: US0109096
- Resource Relation:
- Conference: 1999 Annual Meeting, Boston, MA (US), 06/06/1999--06/10/1999; Other Information: Transactions of the American Nuclear Society; PBD: 6 Jun 1999
- Country of Publication:
- United States
- Language:
- English
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