SciTech Connect

Title: A compact, discrete CsI(Tl) scintillator/Si photodiode gamma camera for breast cancer imaging

A compact, discrete CsI(Tl) scintillator/Si photodiode gamma camera for breast cancer imaging Recent clinical evaluations of scintimammography (radionuclide breast imaging) are promising and suggest that this modality may prove a valuable complement to X-ray mammography and traditional breast cancer detection and diagnosis techniques. Scintimammography, however, typically has difficulty revealing tumors that are less than 1 cm in diameter, are located in the medial part of the breast, or are located in the axillary nodes. These shortcomings may in part be due to the use of large, conventional Anger cameras not optimized for breast imaging. In this thesis I present compact single photon camera technology designed specifically for scintimammography which strives to alleviate some of these limitations by allowing better and closer access to sites of possible breast tumors. Specific applications are outlined. The design is modular, thus a camera of the desired size and geometry can be constructed from an array (or arrays) of individual modules and a parallel hole lead collimator for directional information. Each module consists of: (1) an array of 64 discrete, optically-isolated CsI(Tl) scintillator crystals 3 x 3 x 5 mm{sup 3} in size, (2) an array of 64 low-noise Si PIN photodiodes matched 1-to-1 to the scintillator crystals, (3) an application-specific integrated circuit (ASIC) that amplifies the more » 64 photodiode signals and selects the signal with the largest amplitude, and (4) connectors and hardware for interfacing the module with a motherboard, thereby allowing straightforward computer control of all individual modules within a camera. « less
Authors:
Publication Date:
OSTI Identifier:780592
Report Number(s):LBNL--47620
R&D Project: 445001; TRN: US0102475
DOE Contract Number:AC03-76SF00098
Resource Type:Thesis/Dissertation
Data Type:
Resource Relation:Other Information: TH: Thesis (Ph.D.); Submitted to the Univ. of California, Berkeley, CA (US); Univ. of California, San Francisco, CA (US); PBD: 1 Dec 2000
Research Org:Lawrence Berkeley National Lab., CA (US)
Sponsoring Org:USDOE Director, Office of Science. Office of Biological and Environmental Research. Medical Sciences Division; U.S. Department of Defense, Contract DAMD17-98-1-8302 (US)
Country of Publication:United States
Language:English
Subject: 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; 62 RADIOLOGY AND NUCLEAR MEDICINE; GAMMA CAMERAS; DESIGN; DIAGNOSIS; MAMMARY GLANDS; NEOPLASMS; SCINTILLATOR-PHOTODIODE DETECTORS; CESIUM IODIDES SCINTIMAMMOGRAPHY GAMMA CAMERA