Immunoglobulin variable gene segment V{sub H}81X of the mouse is embedded in L1 transposon sequences
Journal Article
·
· Immunogenetics
OSTI ID:75617
- Univ. of California, San Francisco, A (United States)
L1 elements are widely distributed over the mammalian genome, but the question of their biological significance is still open. The mouse heavy (H) chain variable region V{sub H}81X is overrepresented in the pre-B-cell repertoire; the significance of this is controversial, and V{sub H}81X has been the subject of much research. Here we present data showing that the mouse H chain variable region X{sub H}81X is embedded in the remnants of a LINE-1 element.
- OSTI ID:
- 75617
- Journal Information:
- Immunogenetics, Vol. 41, Issue 2-3; Other Information: PBD: 11 Jan 1995
- Country of Publication:
- United States
- Language:
- English
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