The BALB.B6-Cmv1{sup r} mouse: A strain congenic for Cmv1 and the NK gene complex
Journal Article
·
· Immunogenetics
OSTI ID:75611
- Univ. of Western Australia, Nedlands (Australia)
Genetically determined resistance to murine cytomegalovirus (MCMV) in mice is controlled by both H2 and non-H2 genes. We have identified a phenotypically-defined, autosomal dominant, non-H2 gene, designated Cmvl, that regulates MCMV replication in the spleens of inbred mice. C57BL/6J mice possess the Cmvl{sup r} and exhibit low titers of MCMV replication, whereas the BALB/c strain, which possesses the Cmvl{sup s} allele, exhibits high virus titers in the spleen. 19 refs., 4 figs.
- OSTI ID:
- 75611
- Journal Information:
- Immunogenetics, Vol. 41, Issue 2-3; Other Information: PBD: 11 Jan 1995
- Country of Publication:
- United States
- Language:
- English
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