Early life-stage test in zebrafish versus a growth test in rainbow trout to evaluate toxic effects

Journal Article · Wed May 01 00:00:00 EDT 1991 · Bulletin of Environmental Contamination and Toxicology; (United States)

DOI:https://doi.org/10.1007/BF01689946· OSTI ID:7278809

Bresch, H ^[1]

---

1. Federal Research Centre for Nutrition, Karlsruhe (Germany)

The aim of the work presented in this paper was to compare toxic threshold concentrations of three substances obtained from growth test in rainbow trout (Salmo gairdneri) with data from early life-stages in zebrafish. The growth test was conducted over a period of 7 wk in case of 4-chloroaniline and 4 wk in case of 3,4-dichloroaniline and diazinon. The data from the experiment in zebrafish originate from life-cycle studies; here, only the results obtained within the first 6 wk of development after fertilization are considered. These time limits have been set, as in the FRG a growth test in rainbow trout extending over 4 wk and an early life-stage test in zebrafish extending over 6 wk are being discussed for the Chemical Act.

• OSTI ID: 7278809
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (United States), Vol. 46:5; ISSN 0007-4861
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CHLORINATED AROMATIC HYDROCARBONS
BIOLOGICAL EFFECTS
TROUT
ANIMAL GROWTH
ANILINE
INSECTICIDES
NITRATES
SULFATES
TEMPERATURE EFFECTS
AMINES
ANIMALS
AQUATIC ORGANISMS
AROMATICS
FISHES
GROWTH
HALOGENATED AROMATIC HYDROCARBONS
NITROGEN COMPOUNDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OXYGEN COMPOUNDS
PESTICIDES
SULFUR COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology