Practical iterative reconstruction methods for quantitative cardiac SPECT image reconstruction
- Univ. of North Carolina, Chapel Hill, NC (United States)
The authors proposed a practical iterative reconstruction method for cardiac SPECT imaging. The method consisted of four major parts. First, the first order Chang reconstructed image with attenuation compensation of the chest region was obtained as the initial estimate. The iterative weighted least square-conjugate gradient (WLS-CG) reconstruction algorithm, known for its fast convergence rate, was then applied. A projector/backprojector which modeled the nonuniform attenuation and the spatially variant collimator-detector response was used with the WLS-CG algorithm to provide accurate compensation for the effects of attenuation and collimator-detector response. Finally a smoothing filter was used to suppress noise amplification between interactions. The method was evaluated relative to conventional reconstruction methods in terms of quantitative accuracy, image noise and ventricular wall thickness. The authors conclude that the practical iterative reconstruction method has great potential for clinical use in providing cardiac SPECT images with high quantitative accuracy and low image noise within a few iterations.
- OSTI ID:
- 7233829
- Journal Information:
- IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States), Vol. 41:1 Pt2; ISSN 0018-9499
- Country of Publication:
- United States
- Language:
- English
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