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Title: Prospective study of the effects of ventilation tubes on hearing after radiotherapy for carcinoma of nasopharynx

Journal Article · · Ann. Otol., Rhinol., Laryngol.; (United States)

In patients with nasopharyngeal carcinoma, deafness sometimes occurs following radiotherapy. It is usually conductive, but may be sensorineural. Tinnitus is present frequently and usually is distressing. The role of ventilation tubes (grommets) in relieving these problems was assessed in a prospective randomized controlled trial of 115 patients. In the group with grommets, there was an improvement in hearing, with a reduction of the averaged air-bone gap (p less than .01). This was not found in the control group without ventilation tubes, who developed a larger conductive loss (p less than .01) and, in addition, a slight deterioration of the averaged bone conduction threshold (p less than .01). Surprisingly, the group with grommets did not develop this sensorineural loss (p less than .01). In addition, tinnitus was improved significantly by the insertion of ventilation tubes (p less than .01). Neither necrosis nor stenosis of the external auditory meatus was found in either group.

Research Organization:
Medical and Health Department Institute of Radiology and Oncology (Hong Kong)
OSTI ID:
7195200
Journal Information:
Ann. Otol., Rhinol., Laryngol.; (United States), Vol. 97
Country of Publication:
United States
Language:
English