Triple course external beam radiotherapy for carcinoma of the prostate
In 1976 this hospital began using a triple-course technique of external beam irradiation for localized carcinoma of the prostate. The treatment consisted of 2 courses of 20 Gy in 2 weeks to the pelvis and a third course of 20-25 Gy in 2-2 1/2 weeks as a boost to the prostate. A 2 week rest followed the first and second courses. The results of this treatment technique are reported on the first 50 patients who had been followed for at least 3 years. Although 96% of these patients developed bladder and/or bowel reactions, the majority of the symptoms were in the very mild to mild category, with only 2% severe reactions referrable to each organ. The incidence of late complications in this series compared favorably to those reported by other authors. Clinical local control was 96% while postreatment needle biopsy performed on 22/50 patients yielded a negative rate of 86%. This study has shown that with triple course external beam irradiation, excellent control of localized carcinoma of the prostate can be achieved with minimal acute morbidity.
- Research Organization:
- Eastern Virginia Medical School/Medical Center Hospitals, Norfolk
- OSTI ID:
- 7189766
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
NAUSEA
RADIOINDUCTION
PROCTITIS
PROSTATE
CARCINOMAS
RADIOTHERAPY
SIDE EFFECTS
ULCERS
BLADDER
DIARRHEA
EXTERNAL IRRADIATION
HARD X RADIATION
LARGE INTESTINE
PATIENTS
PELVIS
BODY
BODY AREAS
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
ELECTROMAGNETIC RADIATION
GASTROINTESTINAL TRACT
GLANDS
INTESTINES
IONIZING RADIATIONS
IRRADIATION
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
RADIATIONS
RADIOLOGY
SYMPTOMS
THERAPY
URINARY TRACT
X RADIATION
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)