Silica-fiber microextraction for laser desorption ion trap mass spectrometry
- Los Alamos National Lab., NM (United States)
We have coupled sample collection by solid-phase microextraction on disposable fused silica optical fibers with analysis by laser desorption ion trap mass spectrometry for rapid screening of organic contaminants in complex matrices. Because the silica-fiber probe serves as both the sampling medium and the sample support for laser desorption, traditional methods of sample preparation are eliminated with the expected gains in speed and simplicity. Pyrene was the benchmark compound in these experiments but we show that the technique is also applicable to other polycyclic aromatic hydrocarbons (PAHs) and semivolatile compounds, laser dyes, pesticides, and peptides. Derivatizing the silica fiber improves the analyte collection efficiency, and firing the laser during a ring electrode rf ramp promotes dependable trapping of laser-desorbed ions. 32 refs., 5 figs.
- OSTI ID:
- 7164827
- Journal Information:
- Analytical Chemistry (Washington); (United States), Vol. 66:11; ISSN 0003-2700
- Country of Publication:
- United States
- Language:
- English
Similar Records
Ion trap mass spectrometric detection of laser desorbed ions from derivatized fused silica fibers
Effects of flow rate and temperature on thermal desorbability of polycyclic aromatic hydrocarbons and pesticides from Tenax-GC
Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
DYES
MASS SPECTROSCOPY
PEPTIDES
PESTICIDES
POLYCYCLIC AROMATIC HYDROCARBONS
PYRENE
SILICA
DERIVATIZATION
DESORPTION
EXCIMER LASERS
EXTRACTION
OPTICAL FIBERS
AROMATICS
CHALCOGENIDES
CHEMICAL REACTIONS
CONDENSED AROMATICS
FIBERS
GAS LASERS
HYDROCARBONS
LASERS
MINERALS
ORGANIC COMPOUNDS
OXIDE MINERALS
OXIDES
OXYGEN COMPOUNDS
PROTEINS
SEPARATION PROCESSES
SILICON COMPOUNDS
SILICON OXIDES
SORPTION
SPECTROSCOPY
400201* - Chemical & Physicochemical Properties
400102 - Chemical & Spectral Procedures