Evaluation of the biofragmentable anastomotic ring following preoperative irradiation to the rectosigmoid in dogs

Journal Article · Fri Jan 01 00:00:00 EST 1988 · Dis. Colon Rectum; (United States)

DOI:https://doi.org/10.1007/BF02552561· OSTI ID:7151863

Smith, A D; Bubrick, M P; Mestitz, S T; Crouch, F M; Johnston, G R; Feeney, D A; Strom, R L; Maney, J W

An animal study was done to evaluate the safety of a sutureless colorectal anastomosis in irradiated bowel. Forty mongrel dogs received preoperative radiation with 5000 rads and then underwent a low anterior resection and anastomosis using either the EEA-31TM stapling device, a two-layer handsewn technique, or the biofragmentable anastomotic ring (BAR) 31-1.5 mm and BAR 31-2.0 mm devices. The anastomoses were then evaluated for early and late anastomotic healing and leaks. The results show four radiographic (three clinical) leaks (P less than .05) in the BAR 31-1.5 mm group and one radiographic leak in the handsewn group. No leaks were detected in the EEA or BAR 31-2.0 mm groups. Results indicate that all three techniques can be done safely with this dose of radiation, and gap size (1.5 mm vs. 2.0 mm) is of critical importance when performing a BAR anastomosis in irradiated bowel.

• Research Organization: Hennepin County Medical Center, Minneapolis, MN (USA)
• OSTI ID: 7151863
• Journal Information: Dis. Colon Rectum; (United States), Vol. 31:1
• Country of Publication: United States
• Language: English

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