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Title: Diagnostic accuracy of computed tomography in detecting adrenal metastasis from primary lung cancer

Thesis/Dissertation ·
OSTI ID:7146415

The main study objective was to estimate the diagnostic accuracy of computed tomography (CT) for detection of adrenal metastases from primary lung cancer. A secondary study objective was to measure intra-reader and inter-reader agreement in interpretation of adrenal CT. Results were compared of CT film review and the autopsy findings of the adrenal glands. A five-level CT reading scale was used to assess the effect of various positivity criteria. The diagnostic accuracy of CT for detection of adrenal metastases was characterized by a tradeoff between specificity and sensitivity. At various positivity criteria, high specificity is traded against low sensitivity. The CT inability to detect many metastatic adrenals was related to frequent metastatic spread without morphologic changes of the gland.

Research Organization:
North Carolina Univ., Chapel Hill, NC (USA)
OSTI ID:
7146415
Resource Relation:
Other Information: Thesis (Ph. D.)
Country of Publication:
United States
Language:
English