Diagnostic accuracy of computed tomography in detecting adrenal metastasis from primary lung cancer
The main study objective was to estimate the diagnostic accuracy of computed tomography (CT) for detection of adrenal metastases from primary lung cancer. A secondary study objective was to measure intra-reader and inter-reader agreement in interpretation of adrenal CT. Results were compared of CT film review and the autopsy findings of the adrenal glands. A five-level CT reading scale was used to assess the effect of various positivity criteria. The diagnostic accuracy of CT for detection of adrenal metastases was characterized by a tradeoff between specificity and sensitivity. At various positivity criteria, high specificity is traded against low sensitivity. The CT inability to detect many metastatic adrenals was related to frequent metastatic spread without morphologic changes of the gland.
- Research Organization:
- North Carolina Univ., Chapel Hill, NC (USA)
- OSTI ID:
- 7146415
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ADRENAL GLANDS
METASTASES
COMPUTERIZED TOMOGRAPHY
ACCURACY
LUNGS
NEOPLASMS
DIAGNOSIS
MAN
SENSITIVITY ANALYSIS
SPECIFICITY
ANIMALS
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
MAMMALS
ORGANS
PRIMATES
RESPIRATORY SYSTEM
TOMOGRAPHY
VERTEBRATES
550602* - Medicine- External Radiation in Diagnostics- (1980-)