Testicular tumors: oncologic imaging and diagnosis

Journal Article · Wed Feb 01 00:00:00 EST 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90014-2· OSTI ID:7134597

Heiken, J P; Balfe, D M; McClennan, B L

The extreme radiosensitivity of testicular seminomas plus recent advances in chemotherapy for nonseminomatous tumors and for advanced seminomas have made long term survival possible in the large majority of patients with testis cancer. Since choice of therapy is determined by tumor histology and extent of disease, accurate clinical staging is critical. Computed tomography (CT) of the abdomen and chest is the imaging procedure of choice for staging testis cancer. Clinical staging accuracy of 80 to 90% can be achieved using CT in combination with radio-immunoassays for ..beta..-HCG and AFP. Ultrasonography (US), while less sensitive and specific than CT for determining nodal status, may be useful in thin patients with sparse retroperitoneal fat. Lymphangiography should be reserved for Stage I patients in whom elective treatment of the retroperitoneum is not planned. Follow-up should include serial radioimmunoassays for serum AFP and ..beta..-HCG and periodic CT examinations of the abdomen and chest. In addition, nuclear magnetic resonance (NMR) imaging and radionuclide imaging following injection of radioactively labelled antibodies to AFP and ..beta..-HCG are new techniques which offer great promise for the future.

• Research Organization: Washington Univ. School of Medicine, St. Louis, MO
• OSTI ID: 7134597
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
HCG
RADIOIMMUNOASSAY
NEOPLASMS
CLASSIFICATION
DIAGNOSIS
REVIEWS
TESTES
BIOMEDICAL RADIOGRAPHY
COMPUTERIZED TOMOGRAPHY
ULTRASONOGRAPHY
ABDOMEN
CHEST
BODY
BODY AREAS
DIAGNOSTIC TECHNIQUES
DISEASES
DOCUMENT TYPES
GONADOTROPINS
GONADS
HORMONES
ISOTOPE APPLICATIONS
MALE GENITALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
RADIOASSAY
RADIOLOGY
TOMOGRAPHY
TRACER TECHNIQUES
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