Secondary leukemia with a translocation (8; 21)
Journal Article
·
· Cancer Genet. Cytogenet.; (United States)
The clinical features and cytogenetic changes of acute myeloid leukemia (AML) developing 10 years after radiotherapy and chemotherapy (for osteosarcoma) are described. Features of both de novo AML (FAB M2 morphology, t(8;21), and secondary leukemia (additional cytogenetic changes, resistance to chemotherapy) were present. The importance of differentiation between primary and therapy-linked disease, and the difficulties in making such a distinction, are discussed.
- Research Organization:
- Selly Oak Hospital, Birmingham (England)
- OSTI ID:
- 7130559
- Journal Information:
- Cancer Genet. Cytogenet.; (United States), Vol. 31:2
- Country of Publication:
- United States
- Language:
- English
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Sat Jun 01 00:00:00 EDT 1985
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An unusual translocation t(5;21) (q13;q22) in a case of acute myelogenous leukemia
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Tue Sep 15 00:00:00 EDT 1987
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OSTI ID:7130559
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
MYELOID LEUKEMIA
RADIOINDUCTION
OSTEOSARCOMAS
RADIOTHERAPY
SIDE EFFECTS
CHEMOTHERAPY
DELAYED RADIATION EFFECTS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DISEASES
HEMIC DISEASES
LEUKEMIA
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
RADIATION EFFECTS
RADIOLOGY
SARCOMAS
SKELETAL DISEASES
THERAPY
560151* - Radiation Effects on Animals- Man
MYELOID LEUKEMIA
RADIOINDUCTION
OSTEOSARCOMAS
RADIOTHERAPY
SIDE EFFECTS
CHEMOTHERAPY
DELAYED RADIATION EFFECTS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DISEASES
HEMIC DISEASES
LEUKEMIA
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
RADIATION EFFECTS
RADIOLOGY
SARCOMAS
SKELETAL DISEASES
THERAPY
560151* - Radiation Effects on Animals- Man