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Title: Sex-specific criteria for interpretation of thallium-201 myocardial uptake and washout studies

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:7091047

A study was undertaken to determine the effect of gender on criteria for the quantitative analysis of exercise-redistribution /sup 201/Tl myocardial scintigraphy. The studies of 26 normal females and 23 normal males were subjected to bilinear interpolative background subtraction and horizontal profile analysis. Significant sexual differences were found in both regional uptake ratios and washout rates. These differences primarily reflected a proportionately decreased anterior and upper septal uptake in females, and faster washout in females. Faster myocardial /sup 201/Tl washout rates in females could not be clearly ascribed to either a physiological or artifactual explanation. It is concluded that since important differences exist between males and females in the detected pattern of /sup 201/Tl myocardial uptake and washout, sex-specific criteria may enhance the predictive accuracy of exercise-redistribution /sup 201/Tl myocardial scintigraphy.

Research Organization:
McGill Univ., Quebec
OSTI ID:
7091047
Journal Information:
J. Nucl. Med.; (United States), Vol. 12
Country of Publication:
United States
Language:
English