New sequencers to take on the genome
Journal Article
·
· Science (Washington, D.C.); (United States)
OSTI ID:7070700
DOE is exploring technologies that may allow sequencing thousands of bases a second, for less than a penny a base. There is considerable skepticism about whether that rate can actually be attained anytime soon. At this stage, most efforts are focusing on working out the bugs for the first generation of automated DNA sequencers. Sequencing by conventional techniques, involves generating a series of DNA fragments that vary in length by one nucleotide base-that is, they start at the same point and end at different bases, an A, G, T, or C.
- OSTI ID:
- 7070700
- Journal Information:
- Science (Washington, D.C.); (United States), Vol. 238:4825
- Country of Publication:
- United States
- Language:
- English
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