A user's guide to computer programs for the analysis of cellular survival data

Technical Report · Fri Jan 01 00:00:00 EST 1988

OSTI ID:7067728

Albright, N

Four computer programs have been developed for the analysis of cellular dose-survival data. The programs enable the user to build a computer database of cellular dose-survival data, calculate cell survival with a correction for cell multiplicity at the time of irradiation, fit various survival models to the data by iteratively weighted least squares, calculate standard errors and confidence intervals of fitted survival curve parameters, calculate ratios of the doses for which two or more survival curves have a specified survival level, e.g., oxygen enhancement ratio (OER) and relative biological effectiveness (RBE), calculate ratios of the survival levels of two or more survival curves for a specified dose, calculate the standard errors of these ratios, make plots of data and survival curves on the user's computer terminal, send these plots to a plotter, and save plot information for subsequent plotting by another program. The programs are written in Fortran, run on a VAX computer, and can be used with a variety of graphics devices. 38 refs.

• Research Organization: Lawrence Berkeley Lab., CA (USA)
• DOE Contract Number: AC03-76SF00098
• OSTI ID: 7067728
• Report Number(s): LBL-22347; ON: DE88008419
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DOSE-RESPONSE RELATIONSHIPS
FORECASTING
MATHEMATICAL MODELS
IMPLEMENTATION
CELL KILLING
COMPUTER CODES
COMPUTER GRAPHICS
DATA BASE MANAGEMENT
DOSE EQUIVALENTS
LETHAL DOSES
MANUALS
RBE
STATISTICS
SURVIVAL CURVES
DOCUMENT TYPES
DOSES
MANAGEMENT
MATHEMATICS
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture