A biokinetic model for [sup 222]Rn gas distribution and alpha dose in humans following ingestion
A biokinetic model for absorption and distribution of [sup 222]Rn in the body following ingestion in drinking water was developed. The rate parameters for the model are derived from historical human data reported in experiments of Harley et al. (1958) and Hursh et al. (1965). The biokinetic model fits the human data of Hursh et al. well for whole body retention following ingestion of [sup 222]Rn in water on an empty stomach. The equivalent dose to stem cells for stomach and colon cancer is estimated to be 1.6 [times] 10[sup [minus]9] Sv Bq[sup [minus]1]. The model calculations yield 4 and 3 calculated stomach and colon cancers from continuous intake of water at the estimated US average of 5.5 Bq L[sup [minus]1]. 16 refs., 3 figs., 2 tabs.
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- Journal Article
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- Journal Name: Environment International; (United States); Journal Volume: 20:5
- Country of Publication:
- United States
- 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; RADON 222; ABSORPTION; INGESTION; SPATIAL DISTRIBUTION; BIOLOGICAL MODELS; RETENTION; ALPHA DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DISTRIBUTION; EVEN-EVEN NUCLEI; HEAVY NUCLEI; INTAKE; ISOTOPES; NUCLEI; RADIOISOTOPES; RADON ISOTOPES; SORPTION 560160* -- Radionuclide Effects, Kinetics, & Toxicology
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