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Title: Immobilized cell cross-flow reactor. [Saccharomyces cerevisiae]

Journal Article · · Biotechnol. Bioeng.; (United States)

A cross-current flow reactor was operated using sodium alginate gel entrapped yeast cells (Saccharomyces cerevisiae) under growth conditions. Micron-sized silica, incorporated into the biocatalyst particles (1 mm mean diameter) improved mechanical strength and internal surface adhesion. The process showed decreased productivity and stability at 35/sup 0/C compared to the normal study done at 30/sup 0/C. The increased number of cross flows diminish the product inhibition effect. The residence time distribution shows that the cross-flow bioreactor system can be approximated to either a train of backmixed fermentors in series or a plug flow fermentor with moderate axial dispersion.

Research Organization:
Rutgers Univ., Piscataway, NJ
OSTI ID:
7035739
Journal Information:
Biotechnol. Bioeng.; (United States), Vol. 26:3
Country of Publication:
United States
Language:
English