Conservative management of tumors of the rectum by radiotherapy and local excision

Journal Article · Thu Feb 01 00:00:00 EST 1990 · Diseases of the Colon and Rectum; (USA)

DOI:https://doi.org/10.1007/BF02055538· OSTI ID:7026087

Despretz, J; Otmezguine, Y; Grimard, L; Calitchi, E; Julien, M ^[1]

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1. CHU Henri Mondor, Creteil (France)

Twenty-five patients with invasive adenocarcinoma of the rectum were treated by preoperative external irradiation (35 Gy), local excision, and peroperative placement of a plastic tube loop in the tumor bed for perioperative brachytherapy (20 or 25 Gy). Patients treated were too frail for radical resection (14 patients) or had refused a permanent colostomy (11 patients). With a mean follow-up of 40.5 months, there have been 5 patients with local relapse, 3 of whom had salvage abdominoperineal resections: 2 have no evidence of disease and 1 has developed distant metastatic disease. The 20 patients with local control have normally functioning sphincters; 1 has developed distant metastatic disease. This combined approach was designed to expand the curative role of local resection in carcinoma of the rectum. The surgical techniques are thoroughly described and the potential role and indications of this approach are discussed.

• OSTI ID: 7026087
• Journal Information: Diseases of the Colon and Rectum; (USA), Vol. 33:2; ISSN 0012-3706
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
RADIOTHERAPY
RECTUM
IRIDIUM ISOTOPES
METASTASES
PATIENTS
SURGERY
BODY
DIGESTIVE SYSTEM
DISEASES
GASTROINTESTINAL TRACT
INTESTINES
ISOTOPES
LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
550600 - Medicine