C[sub 60] in model biological systems. A visible-UV absorption study of solvent-dependent parameters and solute aggregation

Journal Article · Thu Mar 31 00:00:00 EST 1994 · Journal of Physical Chemistry; (United States)

DOI:https://doi.org/10.1021/j100064a035· OSTI ID:7019431

Bensasson, R V; Dellinger, M ^[1]; Bienvenue, E; Seta, P ^[2]; Leach, S ^[3]

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1. Museum National d'Histoire Naturelle, Paris (France)
2. Laboratoire de Physico-Chemie des Systemes Polyphases, Montpellier (France)
3. Univ. Paris-Sud, Orsay (France) Observatoire de Paris-Meudon, Meudon (France)

A study was made of the solubilization of C[sub 60] in various solvents and systems of biological interest, i.e., octanols, micelles, and liposomes, using visible-UV absorption spectroscopy as a diagnostic tool. The state of incorporation of C[sub 60] molecules in micellar and colloidal liposome solutions was monitored using a number of spectroscopic criteria of solute-solvent and solute-solute interactions based on comparison with spectra obtained in alkane and octanol solvents and from thin films of C[sub 60]. Spectral red shifts and intensity modifications of C[sub 60] absorption and C[sub 60] aggregation are discussed in terms of environment-dependent physical parameters. The results indicate that C[sub 60] can be dispersed in micellar solutions of Triton X-100 and Triton X-100 R-S, the fullerene molecules being localized in the inner hydrophobic part of the micelles. C[sub 60] was shown to be incorporated, mainly as aggregates, into phosphatidylcholine liposome colloidal solutions. It is concluded that micellar and liposome solutions can be prepared which could be used to transfer individual C[sub 60] molecules, or groups of molecules, to biological cells. 38 refs., 9 figs., 2 tabs.

• OSTI ID: 7019431
• Journal Information: Journal of Physical Chemistry; (United States), Vol. 98:13; ISSN 0022-3654
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
FULLERENES
ABSORPTION
ABSORPTION SPECTRA
AGGLOMERATION
SOLUBILITY
ULTRAVIOLET SPECTRA
VISIBLE SPECTRA
ALKANES
BIOLOGICAL MODELS
COLLOIDS
COMPILED DATA
LECITHINS
LIPOSOMES
MICELLAR SYSTEMS
OCTANOLS
SOLVENTS
SURFACTANTS
THIN FILMS
ALCOHOLS
CARBON
DATA
DISPERSIONS
ELEMENTS
ESTERS
FILMS
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
LIPIDS
NONMETALS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
PHOSPHOLIPIDS
SORPTION
SPECTRA
400201* - Chemical & Physicochemical Properties
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