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Title: PBF/BNCT Program for cancer treatment

Technical Report ·
DOI:https://doi.org/10.2172/7018380· OSTI ID:7018380

Highlights of the PBF/BNCT Program during October include progress in several areas. Included are Gross Boron Analysis in Tissue, Blood, and Urine (Large numbers of samples from Project 2 continue to be processed every month); Analytical Methodologies Development for BSH (Borocaptate Sodium) Purity Determination (Early results from evaluation of 30-cm Nucleosil C-18 columns indicate resistance to degradation by the mobile phase); Boron Microscopic Analytical Development (Analysis of data from boron-treated, U-87 human glioblastoma cells showed expected increased uptake with increased dosage); Noninvasive Boron Quantification Determination (Successful three-dimensional chemical shift imaging of boron in a canine pituitary-tumor patient has been carried out at EIRMC); and Dosimetry (Additional neutron spectrometry measurements using 2.6 atm. hydrogen, proton recoil chamber were taken at the BMRR to supplement foil activation measurements in an effort to more precisely identify overall characteristics of the fast-neutron contamination and streaming).

Research Organization:
EG and G Idaho, Inc., Idaho Falls, ID (United States)
Sponsoring Organization:
DOE/NE
DOE Contract Number:
AC07-76ID01570
OSTI ID:
7018380
Report Number(s):
EGG-BNCT-8353-Vol.3-No.10; ON: DE90006954
Country of Publication:
United States
Language:
English